To Autoregulate or Not to Autoregulate-That is No Longer the Question

Seminars in Pediatric Neurology

Volumn 16, Issue 4, 2009, Pages 207-215

  Greisen, Gorm ^a  

^a Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOREGULATION; BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; CARBON DIOXIDE TENSION; CEREBRAL PALSY; CLINICAL PRACTICE; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; HUMAN; HYPOTHESIS; NEWBORN; OXYGENATION; PREMATURITY; REVIEW; STROKE;

ANGIOTENSIN AMIDE; CEREBRAL HEMORRHAGE; CEREBROVASCULAR CIRCULATION; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HOMEOSTASIS; HUMANS; HYPNOTICS AND SEDATIVES; INFANT; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; NEONATOLOGY;

EID: 70450285345     PISSN: 10719091     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spen.2009.09.002     Document Type: Review

References (76)

1. Friis-Hansen B. Body water compartments in children: Changes during growth and related changes in body composition. Pediatrics 28 (1961) 169-181
2. Cooke R., Lunding M., Lomholdt N.F., et al. Respiratory failure in the newborn. The techniques and results of intermittent positive pressure ventilation. Acta Pædiatrica Scand 56 (1967) 498-508
3. Kamper J., Baekgaard P., Peitersen B., et al. (Treatment of respiratory distress syndrome with continuous positive airway pressure). Ugeskr Laeger 135 (1973) 2207-2211
4. Lassen N.A., and Munck O. The cerebral blood flow in man determined by the use of radioactive krypton. Acta Physiol Scand 33 (1955) 30-49
5. Ingvar D.H., and Lassen N.A. Methods for cerebral blood flow measurements in Man. Br J Anaesth 37 (1965) 216-224
6. Jensen K.B., Hoedt-Rasmussen K., Sveinsdottir E., et al. Regional cerebral blood flow determined by inhalation of xenon-133. Summary of a methodological study. Acta Neurol Scand Suppl 13 (1965) 309-310
7. Lou H.C., Lassen N.A., and Friis-Hansen B. Low cerebral blood flow in hypotensive perinatal distress. Acta Neurol Scand 56 (1977) 343-352
8. Hambleton G., and Wigglesworth J.S. Origin of intraventricular haemorrhage in the preterm infant. Arch Dis Child 51 (1976) 651-659
9. Wigglesworth J.S., and Pape K.E. An integrated model for haemorrhagic and ischaemic lesions in the newborn brain. Early Hum Dev 2 (1978) 179-199
10. Lou H.C., Lassen N.A., and Friis-Hansen B. Impaired autoregulation of cerebral blood flow in the distressed newborn infant. J Pediatr 94 (1979) 118-121
11. Papile L.A., Burstein J., Burstein R., et al. Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birthweights less than 1, 500 gm. J Pediatr 92 (1978) 529-534
12. Lou H.C., Lassen N.A., and Friis-Hansen B. Is arterial hypertension crucial for the development of cerebral haemorrhage in premature infants?. Lancet 1 (1979) 1215-1217
13. Wigglesworth J.S. Prevention of cerebral hemorrhage in preterm infants. Lancet 2 (1979) 256
14. Wigglesworth J.S. Low cerebral blood flow: A risk factor in the neonate. J Pediatr 97 (1980) 513
15. Friis-Hansen B., and Lou H.C. Reply. J Pediatr 97 (1980) 513-514
16. Trolle D. A possible drop in first-week-mortality rate for low-birthweight infants after phenobarbitone treatment. Lancet 2 (1968) 1123-1124
17. Osler M., Faero O., Friis-Hansen B., et al. Prevention of the respiratory distress syndrome (RDS) by antepartum glucocorticoid (betamethasone) therapy combined with phenobarbitone and ritodrine. Dan Med Bull 25 (1978) 225-229
18. Greisen G., and Andreasen P.B. Two-compartment analysis of plasma elimination of phenazone in normals and in patients with cirrhosis of the liver. Acta Pharm Toxicol 38 (1976) 49-52
19. Pape K.E., Blackwell R.J., Cusick G., et al. Ultrasound detection of brain damage in preterm infants. Lancet 1 (1979) 1261-1264
20. Greisen G., and Petersen M.B. Intraventricular haemorrhage and method of delivery of VLBW infants. J Perinat Med 11 (1983) 67-73
21. Wimberley P.D., Lou H.C., Pedersen H., et al. Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn. Abolition by phenobarbitone sedation. Acta Paediatr Scand 71 (1982) 537-542
22. Younkin D.P., Reicich M., Jaggi J., et al. Noninvasive method of estimating human newborn regional cerebral blood flow. J Cereb Blood Flow Metab 2 (1982) 415-420
23. Ment L., Ehrenkranz R.A., Lange R.C., et al. Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage. Pediatrics 68 (1981) 763-769
24. Greisen G., Fredriksen P.S., Mali J., et al. Analysis of cranial 133 xenon clearance in the newborn by the two-compartment model. Scand J Clin Lab Invest 44 (1984) 239-250
25. Greisen G., Ellison P.H., Johansen K., et al. Cerebral blood flow in the newborn infant. Comparison of Doppler ultrasound and 133 xenon clearance. J Pediatr 104 (1984) 411-417
26. Greisen G., Pryds O., Rosén I., et al. Poor reversibility of EEG abnormality in hypotensive, preterm neonates. Acta Paediatr Scand 77 (1988) 785-790
27. Greisen G. Analysis of cerebro-arterial Doppler flow velocity waveforms from newborn infants: Towards an index of cerebro-vascular resistance. J Perinat Med 14 (1986) 181-187
28. Perlman J.M., Hill A., and Volpe J.J. The effect of patent ductus arteriosus on flow velocity in the anterior cerebral arteries: Ductal steal in the premature newborn infant. J Pediatr 99 (1981) 767-771
29. Levene M.I., Sands C., Grindulis H., et al. Comparison of two methods of predicting outcome in perinantal asphyxia. Lancet 1 (1985) 67-69
30. Toet M.C., Lemmers P.M., van Schelven L.J., et al. Cerebral oxygenation and electrical activity after birth asphyxia: Their relation to outcome. Pediatrics 117 (2006) 333-339
31. Lemmers P.M., Toet M.C., and van Bel F. Impact of patent ductus arteriosus and subsequent therapy with indomethacin on cerebral oxygenation in preterm infants. Pediatrics 121 (2008) 142-147
32. Ehehalt S., Kehrer M., Goelz R., et al. Cerebral blood flow volume measurement with ultrasound: Interobserver reproducibility in preterm and term neonates. Ultrasound Med Biol 31 (2005) 191-196
33. Volpe J.J., Herscovitch P., Perlman J.M., et al. Positron emission tomography in the newborn: Extensive impairment of regional cerebral blood flow with intraventricular hemorrhage and hemorrhagic intracerebral involvement. Pediatrics 72 (1983) 589-601
34. Greisen G., and Pryds O. Intravenous 133Xe clearance in preterm neonates with respiratory distress. Internal validation of CBF infinity as a measure of global cerebral blood flow. Scand J Clin Lab Invest 48 (1988) 673-678
35. Greisen G. Cerebral blood flow in preterm infants during the first week of life. Acta Paediatr Scand 75 (1986) 43-51
36. Skov L., Pryds O., and Greisen G. Estimating cerebral blood flow in newborn infants: Comparison of near infrared spectroscopy and 133Xe clearance. Pediatr Res 30 (1991) 570-573
37. Kehrer M., Krageloh-Mann I., Goelz R., et al. The development of cerebral perfusion in healthy preterm and term neonates. Neuropediatrics 34 (2003) 281-286
38. Skov L., Pryds O., Greisen G., et al. Estimation of cerebral venous saturation in newborn infants by near infrared spectroscopy. Pediatr Res 33 (1993) 52-55
39. Buchwald F.F., Kesje K., and Greisen G. Measurement of cerebral oxyhaemoglobin saturation and jugular blood flow in term healthy newborn infants by near-infrared spectroscopy and jugular venous occlusion. Biol Neonate 75 (1999) 96-100
40. Yoxall C.W., and Weindling A.M. Measurement of cerebral oxygen consumption in the human neonate using near infrared spectroscopy: Cerebral oxygen consumption increases with advancing gestational age. Pediatr Res 44 (1998) 283-290
41. Gould S.J., Howard S., Hope P.L., et al. Periventricular intraparenchymal cerebral haemorrhage in preterm infants: The role of venous infarction. J Pathol 151 (1987) 197-202
42. Branston N.M., Ladds A., Symon L., et al. Comparison of the effects of ischaemia on early components of somatosensory evoked potentials in brainstem, thalamus, and cerebral cortex. J Cereb Blood Flow Metab 4 (1984) 68-81
43. 2 changes, and visual evoked potentials in mechanically ventilated infants. Acta Paediatr Scand 76 (1987) 394-400
44. Pryds O., and Greisen G. Preservation of single-flash visual evoked potentials at very low cerebral oxygen delivery in preterm infants. Pediatr Neurol 6 (1990) 151-158
45. Greisen G., Pryds O., and Low C.B.F. Discontinuous EEG activity, and periventricular brain injury in ill, preterm neonates. Brain Dev 11 (1989) 164-168
46. Børch K., and Greisen G. Blood flow distribution in the normal human preterm brain. Pediatr Res 43 (1998) 28-33
47. Miranda M.J., Olofsson K., and Sidaros K. Noninvasive measurements of regional cerebral perfusion in preterm and term neonates by magnetic resonance arterial spin labelling. Pediatr Res 60 (2006) 359-363
48. 2 on cerebral blood flow in preterm infants. J Appl Physiol 48 (1980) 468-472
49. Rahilly P.M. Effects of 2% carbon dioxide. 0.5% carbon dioxide and 100% oxygen on cranial blood flow of the human neonate. Pediatrics 66 (1980) 685-689
50. Greisen G., Munck H., and Lou H.M. Hypocarbia cause ischaemic brain damage in the preterm infant?. Lancet 2 (1986) 460
51. Greisen G., Munck H., and Lou H. Severe hypocarbia in preterm infants and neurodevelopmental deficit. Acta Paediatr Scand 76 (1987) 401-404
52. Calvert S.A., Hoskins E.M., Fong K.W., et al. Etiological factors associated with the development of periventricular leukomalacia. Acta Paediatr Scand 76 (1987) 254-259
53. Vannucci R.C., Towfighi J., Heitjan D.F., et al. Carbon dioxide protects the perinatal brain from hypoxic-ischaemic damage: An experimental study in the immature rat. Pediatrics 95 (1995) 868-874
54. Greisen G., and Vannucci R.C. Is periventricular leukomalacia a result of hypoxic ischaemic injury?. Hypocapnia and the preterm brain. Biol Neonate 79 (2001) 194-200
55. Fritz K.I., Ashraf Q.M., Mishra O.M.P., et al. Effect of moderate hypocapnic ventilation on nuclear DNA fragmentation and energy metabolism in the cerebral cortex of newborn piglets. Pediatr Res 50 (2001) 586-589
56. Pirot A.L., Fritz K.I., Mishra O.P., et al. Effects of severe hypocapnia on expression of bax and bcl-2 proteins, DNA-fragmentation, and membrane peroxidation products in cerebral cortical mitochondria of newborn piglets. J Neonatol 91 (2007) 20-27
57. Lou H.C., Phibbs R.H., Wilson S.L., et al. Hyperventilation at birth may prevent early periventricular haemorrhage. Lancet 1 (1982) 1407-1407
58. Jacobsen T., Grønvall J., Petersen S., et al. "Minitouch" treatment of very low birth weight infants. Acta Paediatr 82 (1993) 934-938
59. Kamper J., and Ringsted C. Early treatment of idiopathic respiratory distress syndrome using binasal continuous positive airway pressure. Acta Paediatr Scand 79 (1990) 581-586
60. Topp M., Uldall P., and Greisen G. Cerebral palsy births in eastern Denmark, 1987-90: Implications for neonatal care. Paediatr Perinat Epidemiol 15 (2001) 271-277
61. Pryds O., Greisen G., Lou H., et al. Heterogeneity of cerebral vasoreactivity in preterm infants supported by mechanical ventilation. J Pediatr 115 (1989) 638-645
62. Pryds O., Greisen G., Lou H., et al. Vasoparalysis is associated with brain damage in asphyxiated term infants. J Pediatr 117 (1990) 119-125
63. Tsuji M., Saul P., du Plessis A., et al. Cerebral intravascular oxygenation correlates with mean arterial pressure in critically ill premature infants. Pediatrics 106 (2000) 625-632
64. Soul J.S., Hammer P.E., Tsuji M., et al. Fluctuating pressure-passivity is common in the cerebral circulation of sick premature infants. Pediatr Res 61 (2007) 467
65. Wong F.Y., Leung T.S., Austin T., et al. Impaired autoregulation in preterm infants identified by using spectially resolved spectroscopy. Pediatrics 121 (2008) e604-e611
66. Greisen G. Autoregulation of cerebral blood flow in newborn babies. Early Hum Dev 81 (2005) 423-428
67. Kluckow M., and Evans N. Low superior vena cava flow and intraventricular haemorrhage in preterm infants. Arch Dis Child Fetal Neonat Ed 82 (2000) F188-F194
68. Hernandez M.J., Hawkins R.A., and Brennan R.W. Sympathetic control of regional cerebral blood flow in the asphyxiated newborn dog. In: Heistad D.D., and Marcus M.L. (Eds). Cerebral Blood Flow, Effects of Nerves and Neurotransmitters (1982), Elsevier, New York 359-366
69. Goblerud J.M., Wagerle L.C., and Delivoria-Papadopoulos M. Sympathetic nerve modulation of regional cerebral blood flow during asphyxia in newborn piglets. Am J Physiol 260 (1991) H1575-H1580
70. Moran M., Miletin J., Pichova K., et al. Cerebral tissue oxygenation index and superior vena cava blood flow in the very low birthweight infant. Acta Paediatr 98 (2009) 43-46
71. Lundstrøm K., Pryds O., and Greisen G. The haemodynamic effects of dopamine and volume expansion in sick preterm infants. Early Hum Dev 57 (2000) 157-163
72. Jayasinghe D., Gill A.B., and Levene M.I. CBF reactivity in hypotensive and normotensive preterm infants. Pediatr Res 54 (2003) 848-853
73. Munro M.J., Walker A.M., and Barfield C.P. Hypotensive extremely low birthweight infants have reduced cerebral blood flow. Pediatrics 114 (2004) 1591-1596
74. Pellicer A., Valverde E., Elorza M.D., et al. Cardiovascular support for low birthweight infants and cerebral hemodynamics: A randomized, blinded, clinical trial. Pediatrics 115 (2005) 1501-1512
75. Møller K., Tofteng F., Quist T., et al. Cerebral blood flow and metabolism during infusion of noradrenaline and propofol in patients with bacterial meningitis. Stroke 35 (2004) 1333-1339
76. Greisen G. Cerebral blood flow in mechanically ventilated preterm infants. Dan Med Bull 37 (1990) 124-132