Local intensity and PCA based detection of virus particle candidates in transmission electron microscopy images

ISPA 2009 - Proceedings of the 6th International Symposium on Image and Signal Processing and Analysis

Volumn , Issue , 2009, Pages 436-441

  Kylberg, Gustaf ^a   Sintorn, Ida Maria ^a   Uppström, Mats ^b   Ryner, Martin ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b VIRONOVA AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON MICROSCOPY IMAGES; GENERAL METHOD; INPUT PARAMETER; INTENSITY INFORMATION; TRANSMISSION ELECTRON MICROSCOPY IMAGES;

SIGNAL DETECTION; SIGNAL PROCESSING; TRANSMISSION ELECTRON MICROSCOPY;

COMPUTER VIRUSES;

EID: 70450248500     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (16)

1. S. Beucher, "The watershed transformation applied to image segmentation", Scanning Microscopy, 6, 1992, pp. 299-314.
2. M. Gentile and H. R. Gelderblom, "Rapid viral diagnosis: role of electron microscopy", New Microbiol., 28(1), 2005, pp. 1-12.
3. P. R. Hazelton and H. R. Gelderblom, "Electron microscopy for rapid diagnosis of infectious agents in emergent situations", Emerg. Infect. Dis., 9(3), 2003, pp. 294-303.
4. G. Kylberg, I.-M. Sintorn, and G. Borgefors, "Towards automated TEM for virus diagnostics: Segmentation of grid squares and detection of regions of interest", In A.-B. Salberg, J. Y. Hardeberg, and R. Jenssen, editors, Image Analysis, volume 5575 of LNCS, pp. 169-178. Springer, 2009.
5. J. Lefman, R. Morrison, and S. Subramaniam, "Automated 100-position specimen loader and image acquisition system for transmission electron microscopy", J. Struct. Biol., 158(3), 2007, pp. 318-326.
6. J. Lei and J. Frank, "Automated acquisition of cryo-electron micrographs for single particle reconstruction on an fei Tecnai electron microscope", J. Struct. Biol., 150(1), 2005, pp. 69-80.
7. R. Malladi, J. A. Sethian, and B. C. Vemuri, "Shape modeling with front propagation: A level set approach", IEEE Trans. Pattern Anal. Mach. Intell., 17, 1995, pp. 158-175.
8. B. Matuszewski and L.-K. Shark, "Hierarchical iterative bayesian approach to automatic recognition of biological viruses in electron microscope images", In Proc. of ICIP 2001, volume 2, pp. 347-350, 2001.
9. B. J. Matuszewski, L.-K. Shark, and G. Hall, "A novel segmentation and classification method for identification of viruses in electron microscope image", In Proc. of IEEE Sixth Int. Conf. on Image Processing and its Applications, pp. 819-823, 1997.
10. L.-K. Shark, B. J. Matuszewski, and G. Hall, "New template matching approach for automatic classification of viruses in electron microscope images", In Proc. of Medical Image Understanding Conf., pp. 965-974, 1998.
11. I.-M. Sintorn, M. Homman-Loudiyi, C. Söderberg-Nauclér, and G. Borgefors, "A refined circular template matching method for classification of human cytomegalovirus capsids in TEM images", Comput. Methods Programs Biomed., 76, 2004, pp. 95-102.
12. M. Sonka, V. Hlavac, and R. Boyle, Image Processing, Analysis, and Machine Vision, chapter 8, pp. 380-390. Brooks/Cole Publishing Company, 2nd edition, 1999.
13. C. Suloway, J. Pulokas, D. Fellmann, A. Cheng, J. S. S. Guerra, F.and Quispe, C. S. Potter, and B. Carragher, "Automated molecular microscopy: The new Leginon system", J. Struct. Biol., 151, 2005, pp. 41-60.
14. E. T. Utagawa, E. Nakazawa, K. Matsuo, I. Oishi, N. Takeda, and T. Miyamura, "Application of an automated specimen search system installed in a transmission electron microscope for the detection of caliciviruses in clinical specimens", J. Virol. Methods, 100(1-2), 2002, pp. 49-56.
15. P. Zhang, A. Beatty, J. L. S. Milne, and S. Subramaniam, "Automated data collection with a Tecnai 12 electron microscope: Applications for molecular imaging by cryomicroscopy", J. Struct. Biol., 135, 2001, pp. 251-261.
16. Y. Zhu, B. Carragher, R. M. Glaeser, D. Fellmann, C. Bajaj, M. Bern, F. Mouche, F. de Haas, R. J. Hall, D. J. Kriegman, S. J. Ludtke, S. P. Mallick, P. A. Penczek, A. M. Roseman, F. J. Sigworth, N. Volkmann, and C. S. Potter, "Automatic particle selection: results of a comparative study", J. Struct. Biol., 145, 2004, pp. 3-14.