Targeted delivery of bleomycin to the brain using photo-chemical internalization of Clostridium perfringens epsilon prototoxin

Journal of Neuro-Oncology

Volumn 95, Issue 3, 2009, Pages 317-329

  Hirschberg, Henry ^a,b   Zhang, Michelle J ^b   Gach, H Michael ^c   Uzal, Francisco A ^d   Peng, Qian ^e   Sun, Chung Ho ^a   Chighvinadze, David ^b   Madsen, Steen J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF NEVADA   (United States)

^c NEVADA CANCER INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Bleomycin; Blood brain barrier; Brain tumor; Clostridium perfringens prototoxin; PDT; Photochemical internalization; Targeted opening

Indexed keywords

BLEOMYCIN; CLOSTRIDIUM PERFRINGENS EPSILON PROTOTOXIN; CLOSTRIDIUM TOXIN; PHOTOSENSITIZING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER SURVIVAL; CANCER TRANSPLANTATION; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIGHT EXPOSURE; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTOCHEMICAL INTERNALIZATION; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BACTERIAL TOXINS; BLEOMYCIN; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; GLIOMA; KAPLAN-MEIERS ESTIMATE; MAGNETIC RESONANCE IMAGING; MALE; NEOPLASM TRANSPLANTATION; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RATS; RATS, INBRED F344;

EID: 70450233712     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-009-9930-4     Document Type: Article

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