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Volumn 27, Issue 10, 2009, Pages 1016-1022

Advances in thymosin β10 research: Differential expression, molecular mechanisms, and clinical implications in cancer and other conditions

Author keywords

Actin; Angiogenesis; Apoptosis; Cancer; Thymosin beta 10; Thymosin beta 4

Indexed keywords

ACTIN BINDING PROTEIN; ANTIINFECTIVE AGENT; GROWTH FACTOR; RAS PROTEIN; RETINOIC ACID; RETINOID; THYMOSIN BETA10; ACTIN; THYMOSIN; THYMOSIN BETA(10);

EID: 70450218162     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357900902849640     Document Type: Review
Times cited : (37)

References (88)
  • 1
    • 20044372562 scopus 로고    scopus 로고
    • Roles of thymosins in cancers and other organ systems
    • DOI 10.1007/s00268-004-7817-2
    • Chen, C.; Li, M.; Yang, H.; Chai, H.; Fisher, W.; Yao, Q. Roles of thymosins in cancers and other organ systems. World J Surg 2005, 29, 264-270. (Pubitemid 40768035)
    • (2005) World Journal of Surgery , vol.29 , Issue.3 , pp. 264-270
    • Chen, C.1    Li, M.2    Yang, H.3    Chai, H.4    Fisher, W.5    Yao, Q.6
  • 3
    • 35348960340 scopus 로고    scopus 로고
    • History of the discovery of the thymosins
    • Goldstein, A.L. History of the discovery of the thymosins. Ann NY Acad Sci 2007, 1112, 1-13.
    • (2007) Ann NY Acad Sci , vol.1112 , pp. 1-13
    • Goldstein, A.L.1
  • 4
    • 35349003196 scopus 로고    scopus 로고
    • Beta-thymosins
    • Hannappel, E. Beta-thymosins. Ann NY Acad Sci 2007, 1112, 21-37.
    • (2007) Ann NY Acad Sci , vol.1112 , pp. 21-37
    • Hannappel, E.1
  • 6
    • 0041305878 scopus 로고    scopus 로고
    • The thymosins. Prothymosin alpha, parathymosin, and beta-thymosins: Structure and function
    • Hannappel, E.; Huff, T. The thymosins. Prothymosin alpha, parathymosin, and beta-thymosins: structure and function. Vitam Horm 2003, 66, 257-296.
    • (2003) Vitam Horm , vol.66 , pp. 257-296
    • Hannappel, E.1    Huff, T.2
  • 9
    • 0028989886 scopus 로고
    • Interactions of beta-thymosins, thymosin beta 4-sulfoxide, and N-terminally truncated thymosin beta 4 with actin studied by equilibrium centrifugation, chemical cross-linking and viscometry
    • Huff, T.; Zerzawy, D.; Hannappel, E. Interactions of beta-thymosins, thymosin beta 4-sulfoxide, and N-terminally truncated thymosin beta 4 with actin studied by equilibrium centrifugation, chemical cross-linking and viscometry. Eur J Biochem 1995, 230, 650-657.
    • (1995) Eur J Biochem , vol.230 , pp. 650-657
    • Huff, T.1    Zerzawy, D.2    Hannappel, E.3
  • 11
    • 42049108997 scopus 로고    scopus 로고
    • The beta-thymosin enigma
    • Sun, H.Q.; Yin, H.L. The beta-thymosin enigma. Ann NY Acad Sci 2007, 1112, 45-55.
    • (2007) Ann NY Acad Sci , vol.1112 , pp. 45-55
    • Sun, H.Q.1    Yin, H.L.2
  • 12
    • 0018394926 scopus 로고
    • The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus
    • Low, T.L.; Thurman, G.B.; McAdoo, M.; McClure, J.; Rossio, J.L.; Naylor, P.H.; Goldstein, A.L. The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus. J Biol Chem 1979, 254, 981-986.
    • (1979) J Biol Chem , vol.254 , pp. 981-986
    • Low, T.L.1    Thurman, G.B.2    McAdoo, M.3    McClure, J.4    Rossio, J.L.5    Naylor, P.H.6    Goldstein, A.L.7
  • 13
    • 0020034995 scopus 로고    scopus 로고
    • Chemical characterization of thymosin beta 4
    • Low, T.L.; Goldstein, A.L. Chemical characterization of thymosin beta 4. J Biol Chem1982, 257, 1000-1006.
    • J Biol Chem1982 , vol.257 , pp. 1000-1006
    • Low, T.L.1    Goldstein, A.L.2
  • 14
    • 0027510119 scopus 로고
    • Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins
    • Yu, F.X.; Lin, S.C.; Morrison-Bogorad, M.; Atkinson, M.A.; Yin, H.L. Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins. J Biol Chem 1993, 268, 502-509.
    • (1993) J Biol Chem , vol.268 , pp. 502-509
    • Yu, F.X.1    Lin, S.C.2    Morrison-Bogorad, M.3    Atkinson, M.A.4    Yin, H.L.5
  • 17
    • 3042574085 scopus 로고    scopus 로고
    • Thymosin beta 10 expression and actin filament organization in tumor cell lines with different metastatic potential
    • Liu, C.R.; Ma, C.S.; Ning, J.Y.; You, J.F.; Liao, S.L.; Zheng, J. Thymosin beta 10 expression and actin filament organization in tumor cell lines with different metastatic potential. Zhonghua Bing Li Xue Za Zhi 2004, 33, 67-71.
    • (2004) Zhonghua Bing Li Xue Za Zhi , vol.33 , pp. 67-71
    • Liu, C.R.1    Ma, C.S.2    Ning, J.Y.3    You, J.F.4    Liao, S.L.5    Zheng, J.6
  • 18
    • 0025775720 scopus 로고
    • Differential expression of thymosin genes in human tumors and in the developing human kidney
    • Hall, A.K. Differential expression of thymosin genes in human tumors and in the developing human kidney. Int J Cancer 1991, 48, 672-677.
    • (1991) Int J Cancer , vol.48 , pp. 672-677
    • Hall, A.K.1
  • 19
    • 0028036953 scopus 로고
    • Amplification-independent overexpression of thymosin beta-10 mRNA in human renal cell carcinoma
    • Hall, A.K. Amplification-independent overexpression of thymosin beta-10 mRNA in human renal cell carcinoma. Ren Fail 1994, 16, 243-254.
    • (1994) Ren Fail , vol.16 , pp. 243-254
    • Hall, A.K.1
  • 20
    • 0027406711 scopus 로고
    • Thymosin beta-10 expression in melanoma cell lines and melanocytic lesions: A new progression marker for human cutaneous melanoma
    • Weterman, M.A.; van Muijen, G.N.; Ruiter, D.J.; Bloemers, H.P. Thymosin beta-10 expression in melanoma cell lines and melanocytic lesions: A new progression marker for human cutaneous melanoma. Int J Cancer 1993, 53, 278-284.
    • (1993) Int J Cancer , vol.53 , pp. 278-284
    • Weterman, M.A.1    Van Muijen, G.N.2    Ruiter, D.J.3    Bloemers, H.P.4
  • 25
    • 0038713732 scopus 로고    scopus 로고
    • Profiling comparison and validation of gene expression in gastric carcinoma and normal stomach
    • Oien, K.A.; Vass, J.K.; Downie, I.; Fullarton, G.; Keith, W.N. Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach. Oncogene 2003, 22, 4287-4300.
    • (2003) Oncogene , vol.22 , pp. 4287-4300
    • Oien, K.A.1    Vass, J.K.2    Downie, I.3    Fullarton, G.4    Keith, W.N.5
  • 28
    • 63349110389 scopus 로고    scopus 로고
    • Thymosin beta 10 is aberrantly expressed in pancreatic cancer and induces JNK activation
    • Li, M.; Zhang, Y.; Zhai, Q.; Feurino, L.W.; Fisher, W.E.; Chen, C.; Yao, Q. Thymosin beta 10 is aberrantly expressed in pancreatic cancer and induces JNK activation. Cancer Invest 2009, 27, 251-256.
    • (2009) Cancer Invest , vol.27 , pp. 251-256
    • Li, M.1    Zhang, Y.2    Zhai, Q.3    Feurino, L.W.4    Fisher, W.E.5    Chen, C.6    Yao, Q.7
  • 29
    • 0036554867 scopus 로고    scopus 로고
    • Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas
    • McDoniels-Silvers, A.L.; Nimri, C.F.; Stoner, G.D.; Lubet, R.A.; You, M. Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas. Clin Cancer Res 2002, 8, 1127-1138.
    • (2002) Clin Cancer Res , vol.8 , pp. 1127-1138
    • McDoniels-Silvers, A.L.1    Nimri, C.F.2    Stoner, G.D.3    Lubet, R.A.4    You, M.5
  • 30
    • 56249127097 scopus 로고    scopus 로고
    • Expression of thymosin beta10 and the role in non-small cell lung cancer
    • Gu, Y.; Wang, C.; Wang, Y.; Qiu, X.; Wang, E. Expression of thymosin beta10 and the role in non-small cell lung cancer. Hum Pathol 2009, 40, 117-124.
    • (2009) Hum Pathol , vol.40 , pp. 117-124
    • Gu, Y.1    Wang, C.2    Wang, Y.3    Qiu, X.4    Wang, E.5
  • 31
    • 0035845856 scopus 로고    scopus 로고
    • Overexpression of the thymosin beta-10 gene in human ovarian cancer cells disrupts F-actin stress fiber and leads to apoptosis
    • Lee, S.H.; Zhang, W.; Choi, J.J.; Cho, Y.S.; Oh, S.H.; Kim, J.W.; Hu, L.; Xu, J.; Liu, J.; Lee, J.H. Overexpression of the thymosin beta-10 gene in human ovarian cancer cells disrupts F-actin stress fiber and leads to apoptosis. Oncogene 2001, 20, 6700-6706.
    • (2001) Oncogene , vol.20 , pp. 6700-6706
    • Lee, S.H.1    Zhang, W.2    Choi, J.J.3    Cho, Y.S.4    Oh, S.H.5    Kim, J.W.6    Hu, L.7    Xu, J.8    Liu, J.9    Lee, J.H.10
  • 33
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark, E.A.; Golub, T.R.; Lander, E.S.; Hynes, R.O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 2000, 406, 532-535.
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 34
    • 0344858002 scopus 로고    scopus 로고
    • Role of thymosin beta4 in tumor metastasis and angiogenesis
    • Cha, H.J.; Jeong, M.J.; Kleinman, H.K. Role of thymosin beta4 in tumor metastasis and angiogenesis. J Natl Cancer Inst 2003, 95, 1674-1680.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1674-1680
    • Cha, H.J.1    Jeong, M.J.2    Kleinman, H.K.3
  • 35
    • 0030722740 scopus 로고    scopus 로고
    • Localization and quantitation of expression of the cell motilityrelated protein thymosin beta15 in human breast tissue
    • Gold, J.S.; Bao, L.; Ghoussoub, R.A.; Zetter, B.R.; Rimm, D.L. Localization and quantitation of expression of the cell motilityrelated protein thymosin beta15 in human breast tissue. Mod Pathol 1997, 10, 1106-1112.
    • (1997) Mod Pathol , vol.10 , pp. 1106-1112
    • Gold, J.S.1    Bao, L.2    Ghoussoub, R.A.3    Zetter, B.R.4    Rimm, D.L.5
  • 36
    • 0031596754 scopus 로고    scopus 로고
    • Thymosin beta 15 expression in tumor cell lines with varying metastatic potential
    • Bao, L.; Loda, M.; Zetter, B.R. Thymosin beta 15 expression in tumor cell lines with varying metastatic potential. Clin Exp Metastasis 1998, 16, 227-233.
    • (1998) Clin Exp Metastasis , vol.16 , pp. 227-233
    • Bao, L.1    Loda, M.2    Zetter, B.R.3
  • 38
    • 39049180972 scopus 로고    scopus 로고
    • Prospects for diagnosis of prostate cancer by biomarkers in the urine
    • Liu, Y.; Geng, D.J. Prospects for diagnosis of prostate cancer by biomarkers in the urine. Zhonghua Nan Ke Xue 2006, 12, 453-455.
    • (2006) Zhonghua Nan Ke Xue , vol.12 , pp. 453-455
    • Liu, Y.1    Geng, D.J.2
  • 39
    • 0030599047 scopus 로고    scopus 로고
    • Thymosin beta10 mRNA expression during early postimplantation mouse development
    • Carpintero, P.; Franco, del. Amo. F.; Anadon, R.; Gomez-Marquez, J. Thymosin beta10 mRNA expression during early postimplantation mouse development. FEBS Lett 1996, 394, 103-106.
    • (1996) FEBS Lett , vol.394 , pp. 103-106
    • Carpintero, P.1    Franco, D.A.F.2    Anadon, R.3    Gomez-Marquez, J.4
  • 40
    • 0025653344 scopus 로고
    • Developmental expression of mRNAs encoding thymosins beta 4 and beta 10 in rat brain and other tissues
    • Lin, S.C.; Morrison-Bogorad, M. Developmental expression of mRNAs encoding thymosins beta 4 and beta 10 in rat brain and other tissues. J Mol Neurosci 1990, 2, 35-44.
    • (1990) J Mol Neurosci , vol.2 , pp. 35-44
    • Lin, S.C.1    Morrison-Bogorad, M.2
  • 41
    • 0028869462 scopus 로고
    • Developmental characterization of thymosin beta 4 and beta 10 expression in enriched neuronal cultures from rat cerebella
    • Voisin, P.J.; Pardue, S.; Morrison-Bogorad, M. Developmental characterization of thymosin beta 4 and beta 10 expression in enriched neuronal cultures from rat cerebella. J Neurochem 1995, 64, 109-120.
    • (1995) J Neurochem , vol.64 , pp. 109-120
    • Voisin, P.J.1    Pardue, S.2    Morrison-Bogorad, M.3
  • 43
    • 0026078166 scopus 로고
    • Developmental regulation of beta-thymosins in the rat central nervous system
    • Lugo, D.I.; Chen, S.C.; Hall, A.K.; Ziai, R.; Hempstead, J.L.; Morgan, J.I. Developmental regulation of beta-thymosins in the rat central nervous system. J Neurochem. 1991, 56, 457-461.
    • (1991) J Neurochem. , vol.56 , pp. 457-461
    • Lugo, D.I.1    Chen, S.C.2    Hall, A.K.3    Ziai, R.4    Hempstead, J.L.5    Morgan, J.I.6
  • 44
    • 0033002763 scopus 로고    scopus 로고
    • 10 gene in normal and kainic acid-treated rat forebrain
    • DOI 10.1016/S0169-328X(99)00115-1, PII S0169328X99001151
    • Carpintero, P.; Anadon, R.; Gomez-Marquez, J. Expression of the thymosin beta10 gene in normal and kainic acid-treated rat forebrain. Brain Res Mol Brain Res 1999, 70, 141-146. (Pubitemid 29278616)
    • (1999) Molecular Brain Research , vol.70 , Issue.1 , pp. 141-146
    • Carpintero, P.1    Anadon, R.2    Gomez-Marquez, J.3
  • 45
    • 18044392377 scopus 로고    scopus 로고
    • Transcriptional profiling using a novel cDNA array identifies differential gene expression during porcine embryo elongation
    • Lee, S.H.; Zhao, S.H.; Recknor, J.C.; Nettleton, D.; Orley, S.; Kang, S.K.; Lee, B.C.; Hwang, W.S.; Tuggle, C.K. Transcriptional profiling using a novel cDNA array identifies differential gene expression during porcine embryo elongation. Mol Reprod Dev 2005, 71, 129-139.
    • (2005) Mol Reprod Dev , vol.71 , pp. 129-139
    • Lee, S.H.1    Zhao, S.H.2    Recknor, J.C.3    Nettleton, D.4    Orley, S.5    Kang, S.K.6    Lee, B.C.7    Hwang, W.S.8    Tuggle, C.K.9
  • 46
    • 0025372541 scopus 로고
    • Thymosin beta 10 levels in developing human brain and its regulation by retinoic acid in the HTB-10 neuroblastoma
    • Hall, A.K.; Hempstead, J.; Morgan, J.I. Thymosin beta 10 levels in developing human brain and its regulation by retinoic acid in the HTB-10 neuroblastoma. Brain Res Mol Brain Res 1990, 8, 129-135.
    • (1990) Brain Res Mol Brain Res , vol.8 , pp. 129-135
    • Hall, A.K.1    Hempstead, J.2    Morgan, J.I.3
  • 47
    • 0025917579 scopus 로고
    • Developmental regulation of thymosin beta 10 mRNA in the human brain
    • Hall, A.K. Developmental regulation of thymosin beta 10 mRNA in the human brain. Brain Res Mol Brain Res 1991, 9, 175-177.
    • (1991) Brain Res Mol Brain Res , vol.9 , pp. 175-177
    • Hall, A.K.1
  • 49
    • 0043167780 scopus 로고    scopus 로고
    • Inflammatory mediators expressed in human islets of Langerhans: Implications for islet transplantation
    • Johansson, U.; Olsson, A.; Gabrielsson, S.; Nilsson, B.; Korsgren, O. Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation. Biochem Biophys Res Commun 2003, 308, 474-479.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 474-479
    • Johansson, U.1    Olsson, A.2    Gabrielsson, S.3    Nilsson, B.4    Korsgren, O.5
  • 53
    • 0036130698 scopus 로고    scopus 로고
    • Upregulation of thymosin beta-10 by Mycobacterium bovis infection of bovine macrophages is associated with apoptosis
    • Gutierrez-Pabello, J.A.; McMurray, D.N.; Adams, L.G. Upregulation of thymosin beta-10 by Mycobacterium bovis infection of bovine macrophages is associated with apoptosis. Infect Immun 2002, 70, 2121-2127.
    • (2002) Infect Immun , vol.70 , pp. 2121-2127
    • Gutierrez-Pabello, J.A.1    McMurray, D.N.2    Adams, L.G.3
  • 54
    • 0034024191 scopus 로고    scopus 로고
    • C-terminal variations in beta-thymosin family members specify functional differences in actin-binding properties
    • Eadie, J.S.; Kim, S.W.; Allen, P.G.; Hutchinson, L.M.; Kantor, J.D.; Zetter, B.R. C-terminal variations in beta-thymosin family members specify functional differences in actin-binding properties. J Cell Biochem 2000, 77, 277-287.
    • (2000) J Cell Biochem , vol.77 , pp. 277-287
    • Eadie, J.S.1    Kim, S.W.2    Allen, P.G.3    Hutchinson, L.M.4    Kantor, J.D.5    Zetter, B.R.6
  • 55
    • 0343852690 scopus 로고    scopus 로고
    • C-terminal truncation of thymosin beta10 by an intracellular protease and its influence on the interaction with G-actin studied by ultrafiltration
    • Huff, T.; Muller, C.S.; Hannappel, E. C-terminal truncation of thymosin beta10 by an intracellular protease and its influence on the interaction with G-actin studied by ultrafiltration. FEBS Lett 1997, 414, 39-44.
    • (1997) FEBS Lett , vol.414 , pp. 39-44
    • Huff, T.1    Muller, C.S.2    Hannappel, E.3
  • 56
    • 0028489887 scopus 로고
    • Beta thymosins as actin binding peptides
    • Safer, D.; Nachmias, V.T. Beta thymosins as actin binding peptides. Bioessays 1994, 16, 473-1449
    • (1994) Bioessays , vol.16 , pp. 473-1449
    • Safer, D.1    Nachmias, V.T.2
  • 57
    • 35348931520 scopus 로고    scopus 로고
    • Models of the actin-bound forms of the beta-thymosins
    • Xue, B.; Aguda, A.H.; Robinson, R.C. Models of the actin-bound forms of the beta-thymosins. Ann NY Acad Sci 2007, 1112, 56-66.
    • (2007) Ann NY Acad Sci , vol.1112 , pp. 56-66
    • Xue, B.1    Aguda, A.H.2    Robinson, R.C.3
  • 60
    • 33644835262 scopus 로고    scopus 로고
    • The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins
    • Aguda, A.H.; Xue, B.; Irobi, E.; Pŕeat, T. ; Robinson, R.C. The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins. Structure 2006, 14, 469-476.
    • (2006) Structure , vol.14 , pp. 469-476
    • Aguda, A.H.1    Xue, B.2    Irobi, E.3    Pŕeat, T.4    Robinson, R.C.5
  • 61
    • 35348969696 scopus 로고    scopus 로고
    • The beta-thymosin/WH2 fold: Multifunctionality and structure
    • Dominguez, R. The beta-thymosin/WH2 fold: Multifunctionality and structure. Ann NY Acad Sci 2007, 1112, 86-94.
    • (2007) Ann NY Acad Sci , vol.1112 , pp. 86-94
    • Dominguez, R.1
  • 62
    • 0028174199 scopus 로고
    • Effects of thymosin beta 4 and thymosin beta 10 on actin structures in living cells
    • Yu, F.X.; Lin, S.C.; Morrison-Bogorad, M.; Yin, H.L. Effects of thymosin beta 4 and thymosin beta 10 on actin structures in living cells. Cell Motil Cytoskeleton 1994, 27, 13-25.
    • (1994) Cell Motil Cytoskeleton , vol.27 , pp. 13-25
    • Yu, F.X.1    Lin, S.C.2    Morrison-Bogorad, M.3    Yin, H.L.4
  • 63
    • 0029870891 scopus 로고    scopus 로고
    • Beta-thymosins are not simple actin monomer buffering proteins. Insights from overexpression studies
    • Sun, H.Q.; Kwiatkowska, K.; Yin, H.L. Beta-thymosins are not simple actin monomer buffering proteins. Insights from overexpression studies. J Biol Chem 1996, 271, 9223-9230.
    • (1996) J Biol Chem , vol.271 , pp. 9223-9230
    • Sun, H.Q.1    Kwiatkowska, K.2    Yin, H.L.3
  • 64
    • 0026356395 scopus 로고
    • Cloning and characterization of a testis-specific thymosin beta 10 cDNA. Expression in post-meiotic male germ cells
    • Lin, S.C.; Morrison-Bogorad, M. Cloning and characterization of a testis-specific thymosin beta 10 cDNA. Expression in post-meiotic male germ cells. J Biol Chem 1991, 266, 23347-23353.
    • (1991) J Biol Chem , vol.266 , pp. 23347-23353
    • Lin, S.C.1    Morrison-Bogorad, M.2
  • 65
    • 33845745715 scopus 로고    scopus 로고
    • Localization of thymosin beta10 in breast cancer cells: Relationship to actin cytoskeletal remodeling and cell motility
    • Maelan, A.E.; Rasmussen, T.K.; Larsson, L.I. Localization of thymosin beta10 in breast cancer cells: relationship to actin cytoskeletal remodeling and cell motility. Histochem Cell Biol 2007, 127, 109-113.
    • (2007) Histochem Cell Biol , vol.127 , pp. 109-113
    • Maelan, A.E.1    Rasmussen, T.K.2    Larsson, L.I.3
  • 66
    • 11244270824 scopus 로고    scopus 로고
    • Thymosin beta 10 inhibits angiogenesis and tumor growth by interfering with Ras function
    • Lee, S.H.; Son, M.J.; Oh, S.H.; Rho, S.B.; Park, K.; Kim, Y.J.; Park, M.S.; Lee, J.H. Thymosin beta 10 inhibits angiogenesis and tumor growth by interfering with Ras function. Cancer Res 2005, 65, 137-148.
    • (2005) Cancer Res , vol.65 , pp. 137-148
    • Lee, S.H.1    Son, M.J.2    Oh, S.H.3    Rho, S.B.4    Park, K.5    Kim, Y.J.6    Park, M.S.7    Lee, J.H.8
  • 68
    • 35748956386 scopus 로고    scopus 로고
    • Thymosin beta4 and angiogenesis: Modes of action and therapeutic potential
    • Smart, N.; Rossdeutsch, A.; Riley, P.R. Thymosin beta4 and angiogenesis: Modes of action and therapeutic potential. Angiogenesis 2007, 10, 229-241.
    • (2007) Angiogenesis , vol.10 , pp. 229-241
    • Smart, N.1    Rossdeutsch, A.2    Riley, P.R.3
  • 69
    • 33645525974 scopus 로고    scopus 로고
    • Thymosin beta10 inhibits cell migration and capillary-like tube formation of human coronary artery endothelial cells
    • Mu, H.; Ohashi, R.; Yang, H.; Wang, X.; Li, M.; Lin, P.; Yao, Q. Chen, C. Thymosin beta10 inhibits cell migration and capillary-like tube formation of human coronary artery endothelial cells. Cell Motil Cytoskeleton 2006, 63, 222-230.
    • (2006) Cell Motil Cytoskeleton , vol.63 , pp. 222-230
    • Mu, H.1    Ohashi, R.2    Yang, H.3    Wang, X.4    Li, M.5    Lin, P.6    Yao, Q.7    Chen, C.8
  • 70
    • 0035130153 scopus 로고    scopus 로고
    • Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: Evidence for senescent endothelial cells in vivo at sites of atherosclerosis
    • Vasile, E.; Tomita, Y.; Brown, L.F.; Kocher, O.; Dvorak, H.F. Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. FASEB J 2001, 15, 458-466.
    • (2001) FASEB J , vol.15 , pp. 458-466
    • Vasile, E.1    Tomita, Y.2    Brown, L.F.3    Kocher, O.4    Dvorak, H.F.5
  • 73
    • 0028819945 scopus 로고
    • Thymosin beta-10 accelerates apoptosis
    • Hall, A.K. Thymosin beta-10 accelerates apoptosis. Cell Mol Biol Res 1995, 41, 167-180.
    • (1995) Cell Mol Biol Res , vol.41 , pp. 167-180
    • Hall, A.K.1
  • 75
    • 0028024709 scopus 로고
    • Molecular interactions between G-actin DNase i and the beta-thymosins in apoptosis: A hypothesis
    • Hall, A.K. Molecular interactions between G-actin, DNase I and the beta-thymosins in apoptosis: A hypothesis. Med Hypotheses 1994, 43, 125-131.
    • (1994) Med Hypotheses , vol.43 , pp. 125-131
    • Hall, A.K.1
  • 76
    • 1642450634 scopus 로고    scopus 로고
    • The interaction between E-tropomodulin and thymosin beta-10 rescues tumor cells from thymosin beta-10 mediated apoptosis by restoring actin architecture
    • Rho, S.B.; Chun, T.; Lee, S.H.; Park, K.; Lee, J.H. The interaction between E-tropomodulin and thymosin beta-10 rescues tumor cells from thymosin beta-10 mediated apoptosis by restoring actin architecture. FEBS Lett 2004, 557, 57-63.
    • (2004) FEBS Lett , vol.557 , pp. 57-63
    • Rho, S.B.1    Chun, T.2    Lee, S.H.3    Park, K.4    Lee, J.H.5
  • 77
    • 26644473191 scopus 로고    scopus 로고
    • The identification of apoptosis-related residues in human thymosin beta-10 by mutational analysis and computational modeling
    • Rho, S.B.; Lee, K.W.; Chun, T.; Lee, S.H.; Park, K.; Lee, J.H. The identification of apoptosis-related residues in human thymosin beta-10 by mutational analysis and computational modeling. J Biol Chem 2005, 280, 34003-34007.
    • (2005) J Biol Chem , vol.280 , pp. 34003-34007
    • Rho, S.B.1    Lee, K.W.2    Chun, T.3    Lee, S.H.4    Park, K.5    Lee, J.H.6
  • 78
    • 2142763869 scopus 로고    scopus 로고
    • Thymosin-beta4 inhibits corneal epithelial cell apoptosis after ethanol exposure in vitro
    • Sosne, G.; Siddiqi, A.; Kurpakus-Wheater, M. Thymosin-beta4 inhibits corneal epithelial cell apoptosis after ethanol exposure in vitro. Invest Ophthalmol Vis Sci 2004, 45, 1095-1100.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1095-1100
    • Sosne, G.1    Siddiqi, A.2    Kurpakus-Wheater, M.3
  • 80
    • 18844387354 scopus 로고    scopus 로고
    • Development of a sensitive and specific enzyme-linked immunosorbent assay for thymosin beta15, a urinary biomarker of human prostate cancer
    • Hutchinson, L.M.; Chang, E.L.; Becker, C.M.; Ushiyama, N.; Behonick, D.; Shih, M.C.; DeWolf, W.C.; Gaston, S.M.; Zetter, B.R. Development of a sensitive and specific enzyme-linked immunosorbent assay for thymosin beta15, a urinary biomarker of human prostate cancer. Clin Biochem 2005, 38, 558-571.
    • (2005) Clin Biochem , vol.38 , pp. 558-571
    • Hutchinson, L.M.1    Chang, E.L.2    Becker, C.M.3    Ushiyama, N.4    Behonick, D.5    Shih, M.C.6    Dewolf, W.C.7    Gaston, S.M.8    Zetter, B.R.9
  • 81
    • 0026029733 scopus 로고
    • Retinoic acid regulates thymosin beta 10 levels in rat neuroblastoma cells
    • Hall, A.K.; Chen, S.C.; Hempstead, J.L.; Morgan, J.I. Retinoic acid regulates thymosin beta 10 levels in rat neuroblastoma cells. J Neurochem 1991, 56, 462-468.
    • (1991) J Neurochem , vol.56 , pp. 462-468
    • Hall, A.K.1    Chen, S.C.2    Hempstead, J.L.3    Morgan, J.I.4
  • 82
    • 0026472792 scopus 로고
    • Influence of cyclic AMP and serum factors upon expression of a retinoid-responsive gene in neuroblastoma cells
    • Hall, A.K. Influence of cyclic AMP and serum factors upon expression of a retinoid-responsive gene in neuroblastoma cells. J Mol Neurosci 1992, 3, 155-163.
    • (1992) J Mol Neurosci , vol.3 , pp. 155-163
    • Hall, A.K.1
  • 83
    • 0026607717 scopus 로고
    • Retinoids and a retinoic acid receptor differentially modulate thymosin beta 10 gene expression in transfected neuroblastoma cells
    • Hall, A.K. Retinoids and a retinoic acid receptor differentially modulate thymosin beta 10 gene expression in transfected neuroblastoma cells. Cell Mol Neurobiol 1992, 12, 45-58.
    • (1992) Cell Mol Neurobiol , vol.12 , pp. 45-58
    • Hall, A.K.1
  • 84
    • 0035914267 scopus 로고    scopus 로고
    • Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line
    • Pedersen, M.W.; Thykjaer, T.; Orntoft, T.F.; Damstrup, L.; Poulsen, H.S. Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line. Br J Cancer 2001, 85, 1211-1218.
    • (2001) Br J Cancer , vol.85 , pp. 1211-1218
    • Pedersen, M.W.1    Thykjaer, T.2    Orntoft, T.F.3    Damstrup, L.4    Poulsen, H.S.5
  • 86
    • 0036272150 scopus 로고    scopus 로고
    • Chemotherapeutic drugs change actin skeleton organization and the expression of beta-thymosins in human breast cancer cells
    • Otto, A.M.; Muller, C.S.; Huff, T.; Hannappel, E. Chemotherapeutic drugs change actin skeleton organization and the expression of beta-thymosins in human breast cancer cells. J Cancer Res Clin Oncol2002, 128, 247-256.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 247-256
    • Otto, A.M.1    Muller, C.S.2    Huff, T.3    Hannappel, E.4
  • 87
    • 0033052886 scopus 로고    scopus 로고
    • Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: Drug-western
    • Tanaka, H.; Ohshima, N.; Hidaka, H. Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: drug-western. Mol Pharmacol. 1999, 55, 356-363.
    • (1999) Mol Pharmacol. , vol.55 , pp. 356-363
    • Tanaka, H.1    Ohshima, N.2    Hidaka, H.3
  • 88
    • 33751084312 scopus 로고    scopus 로고
    • In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomics
    • Huang, C.M.; Wang, C.C.; Barnes, S.; Elmets, C.A. In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomics. Proteomics 2006, 6, 5805-5814.
    • (2006) Proteomics , vol.6 , pp. 5805-5814
    • Huang, C.M.1    Wang, C.C.2    Barnes, S.3    Elmets, C.A.4


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