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Volumn 6, Issue 4, 2009, Pages 249-256

The cannabinoid R()methanandamide induces IL-6 secretion by prostate cancer PC3 cells

Author keywords

Cannabinoids; Ceramide; IL 6; PC3 cells; Prostate cancer

Indexed keywords

5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ANDROGEN; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR; CAPSAZEPINE; CERAMIDE; FUMONISIN B1; INTERLEUKIN 6; METHANANDAMIDE; RIMONABANT; SMALL INTERFERING RNA;

EID: 70450216539     PISSN: 1547691X     EISSN: 1547691X     Source Type: Journal    
DOI: 10.3109/15476910903241696     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 66349086742 scopus 로고    scopus 로고
    • Bioactive sphingolipids: Metabolism and function
    • Bartke, N., and Hannun, Y.A. 2009. Bioactive sphingolipids: Metabolism and function. J. Lipid Res. 50:S91-S96.
    • (2009) J. Lipid Res. , vol.50
    • Bartke, N.1    Hannun, Y.A.2
  • 3
    • 0035892633 scopus 로고    scopus 로고
    • Determination of ceramides and diglycerides by the diglyceride kinase assay
    • Bielawska, A., Perry, D.K., and Hannun, Y.A. 2001. Determination of ceramides and diglycerides by the diglyceride kinase assay. Anal. Biochem. 298:141-150.
    • (2001) Anal. Biochem. , vol.298 , pp. 141-150
    • Bielawska, A.1    Perry, D.K.2    Hannun, Y.A.3
  • 4
    • 0036278032 scopus 로고    scopus 로고
    • Targeting the endocannabinoid system in cancer therapy: A call for further research
    • Bifulco, M., and Di Marzo, V. 2002. Targeting the endocannabinoid system in cancer therapy: A call for further research. Nat Med. 8:547-550.
    • (2002) Nat Med. , vol.8 , pp. 547-550
    • Bifulco, M.1    Di Marzo, V.2
  • 6
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E.G., and Dyer, W.J. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 7
    • 63049105150 scopus 로고    scopus 로고
    • Emerging role of the cannabinoid receptor CB2 in immune regulation: Therapeutic prospects for neuroinflammation
    • Cabral, G.A., and Griffin-Thomas, L. 2009. Emerging role of the cannabinoid receptor CB2 in immune regulation: Therapeutic prospects for neuroinflammation. Expert Rev. Mol. Med. 11:e3.
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Cabral, G.A.1    Griffin-Thomas, L.2
  • 8
    • 33746138649 scopus 로고    scopus 로고
    • Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes
    • Carracedo, A., Gironella, M., Lorente, M., Garcia, S., Guzman, M., Velasco, G., and Iovanna, J.L. 2006. Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. Cancer Res. 66:6748-6755.
    • (2006) Cancer Res. , vol.66 , pp. 6748-6755
    • Carracedo, A.1    Gironella, M.2    Lorente, M.3    Garcia, S.4    Guzman, M.5    Velasco, G.6    Iovanna, J.L.7
  • 10
    • 64349094002 scopus 로고    scopus 로고
    • Understanding the epidemiology, natural history, and key pathways involved in prostate cancer
    • Crawford, E.D. 2009. Understanding the epidemiology, natural history, and key pathways involved in prostate cancer. Urology 73:S4-S10.
    • (2009) Urology , vol.73
    • Crawford, E.D.1
  • 11
    • 23044486763 scopus 로고    scopus 로고
    • Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases?
    • Croxford, J.L., and Yamamura, T. 2005. Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases? J. Neuroimmunol. 166:3-18.
    • (2005) J Neuroimmunol. , vol.166 , pp. 3-18
    • Croxford, J.L.1    Yamamura, T.2
  • 12
    • 0034001560 scopus 로고    scopus 로고
    • Cannabimimetic fatty acid derivatives in cancer and inflammation
    • DOI 10.1016/S0090-6980(00)00054-X, PII S009069800000054X
    • Di Marzo, V., Melck, D., De Petrocellis, L., and Bisogno, T. 2000. Cannabimimetic fatty acid derivatives in cancer and inflammation. Prostaglandins Lipid Med. 61:43-61. (Pubitemid 30216488)
    • (2000) Prostaglandins and Other Lipid Mediators , vol.61 , Issue.1-2 , pp. 43-61
    • Di Marzo, V.1    Melck, D.2    De Petrocellis, L.3    Bisogno, T.4
  • 13
    • 33645794041 scopus 로고    scopus 로고
    • The biosynthesis, fate, and pharmacological properties of endocannabinoids
    • [Handbook Exp. Pharmacol. (Pertwee, R., Ed.), Berlin: Springer- Verlag
    • Di Marzo, V., De Petrocellis, L., and Bisogno, T. 2005. The biosynthesis, fate, and pharmacological properties of endocannabinoids. In: Cannabinoids [Handbook Exp. Pharmacol., Vol. 168 (Pertwee, R., Ed.), Berlin: Springer- Verlag, pp. 147-185.
    • (2005) Cannabinoids , vol.168 , pp. 147-185
    • Di Marzo, V.1    De Petrocellis, L.2    Bisogno, T.3
  • 14
    • 21644456607 scopus 로고    scopus 로고
    • Signal transduction activated by cannabinoid receptors
    • Diaz-Laviada, I., and Ruiz-Llorente, L. 2005. Signal transduction activated by cannabinoid receptors. Mini Rev. Med. Chem. 5:619-630.
    • (2005) Mini Rev. Med. Chem. , vol.5 , pp. 619-630
    • Diaz-Laviada, I.1    Ruiz-Llorente, L.2
  • 15
    • 58549110631 scopus 로고    scopus 로고
    • R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase- 2-dependent pathway
    • Eichele, K., Ramer, R., and Hinz, B. 2009. R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase- 2-dependent pathway. Pharm. Res. 26:346-355.
    • (2009) Pharm. Res. , vol.26 , pp. 346-355
    • Eichele, K.1    Ramer, R.2    Hinz, B.3
  • 16
    • 51349098155 scopus 로고    scopus 로고
    • Cytokines as a key component of cancer-related inflammation
    • Germano, G., Allavena, P., and Mantovani, A. 2008. Cytokines as a key component of cancer-related inflammation. Cytokine 43:374-379.
    • (2008) Cytokine , vol.43 , pp. 374-379
    • Germano, G.1    Allavena, P.2    Mantovani, A.3
  • 17
    • 33744913027 scopus 로고    scopus 로고
    • The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway
    • Herrera, B., Carracedo, A., Diez-Zaera, M., Gomez del Pulgar, T., Guzman, M., and Velasco, G. 2006. The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. Exp. Cell Res. 312:2121-2131.
    • (2006) Exp. Cell Res. , vol.312 , pp. 2121-2131
    • Herrera, B.1    Carracedo, A.2    Diez-Zaera, M.3    Gomez Del Pulgar, T.4    Guzman, M.5    Velasco, G.6
  • 18
    • 45849135945 scopus 로고    scopus 로고
    • Therapeutic potential of cannabis in pain medicine
    • Hosking, R.D., and Zajicek, J.P. 2008. Therapeutic potential of cannabis in pain medicine. Br. J. Anesth. 101:59-68.
    • (2008) Br. J. Anesth. , vol.101 , pp. 59-68
    • Hosking, R.D.1    Zajicek, J.P.2
  • 20
    • 30344435318 scopus 로고    scopus 로고
    • Ceramide-1-phosphate: The "missing" link in eicosanoid biosynthesis and inflammation
    • Lamour, N.F., and Chalfant, C.E. 2005. Ceramide-1-phosphate: The "missing" link in eicosanoid biosynthesis and inflammation. Mol. Interv. 5:358-367.
    • (2005) Mol. Interv. , vol.5 , pp. 358-367
    • Lamour, N.F.1    Chalfant, C.E.2
  • 21
    • 53149114835 scopus 로고    scopus 로고
    • A review of the world cannabis situation
    • Leggett, T. 2006. A review of the world cannabis situation. Bull. Narc. 58:1-155.
    • (2006) Bull. Narc. , vol.58 , pp. 1-155
    • Leggett, T.1
  • 23
    • 57749188229 scopus 로고    scopus 로고
    • Capsaicin, a component of red peppers, induces expression of androgen receptor via PI3K and MAPK pathways in prostate LNCaP cells
    • Malagarie-Cazenave, S., Olea-Herrero, N., Vara, D., and Diaz-Laviada, I. 2009. Capsaicin, a component of red peppers, induces expression of androgen receptor via PI3K and MAPK pathways in prostate LNCaP cells. FEBS Lett. 583:141-147.
    • (2009) FEBS Lett. , vol.583 , pp. 141-147
    • Malagarie-Cazenave, S.1    Olea-Herrero, N.2    Vara, D.3    Diaz-Laviada, I.4
  • 27
    • 56749151293 scopus 로고    scopus 로고
    • Th17 cells in immunity and autoimmunity
    • Oukka, M. 2008. Th17 cells in immunity and autoimmunity. Ann. Rheum. Dis. 67(S3):26-29.
    • (2008) Ann. Rheum. Dis. , vol.67 , Issue.S3 , pp. 26-29
    • Oukka, M.1
  • 29
    • 84884474728 scopus 로고    scopus 로고
    • Pharmacological actions of cannabinoids
    • [Handbook Exp. Pharmacol., (Pertwee, R., Ed.), Berlin: Springer- Verlag
    • Pertwee, R.G. 2005. Pharmacological actions of cannabinoids. In: Cannabinoids [Handbook Exp. Pharmacol., Vol. 168 (Pertwee, R., Ed.), Berlin: Springer- Verlag, pp. 1-51.
    • (2005) Cannabinoids , vol.168 , pp. 1-51
    • Pertwee, R.G.1
  • 30
    • 33645502759 scopus 로고    scopus 로고
    • The pharmacology of cannabinoid receptors and their ligands: An overview
    • (London)
    • Pertwee, R.G. 2006. The pharmacology of cannabinoid receptors and their ligands: An overview. Int. J. Obesity (London) 30(Suppl. 1):S13-S18.
    • (2006) Int. J. Obesity , vol.30 , Issue.SUPPL. 1
    • Pertwee, R.G.1
  • 31
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee, R.G. 2009. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br. J. Pharmacol. 156:397-411.
    • (2009) Br. J. Pharmacol. , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 34
    • 58149277751 scopus 로고    scopus 로고
    • Roles of bioactive sphingolipids in cancer biology and therapeutics
    • Saddoughi, S.A., Song, P., and Ogretmen, B. 2008. Roles of bioactive sphingolipids in cancer biology and therapeutics. Subcell. Biochem. 49:413-440.
    • (2008) Subcell. Biochem. , vol.49 , pp. 413-440
    • Saddoughi, S.A.1    Song, P.2    Ogretmen, B.3
  • 35
    • 17144470224 scopus 로고    scopus 로고
    • Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction
    • Sanchez, M.G., Ruiz-Llorente, L., Sanchez, A.M., and Diaz-Laviada, I. 2003. Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction. Cell Signal 15:851-869.
    • (2003) Cell Signal , vol.15 , pp. 851-869
    • Sanchez, M.G.1    Ruiz-Llorente, L.2    Sanchez, A.M.3    Diaz-Laviada, I.4
  • 37
    • 34848895758 scopus 로고    scopus 로고
    • Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation
    • Sanchez, A.M., Malagarie-Cazenave, S., Olea, N., Vara, D., Chiloeches, A., and Diaz-Laviada, I. 2007. Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation. Apoptosis 12:2013-2024.
    • (2007) Apoptosis , vol.12 , pp. 2013-2024
    • Sanchez, A.M.1    Malagarie-Cazenave, S.2    Olea, N.3    Vara, D.4    Chiloeches, A.5    Diaz-Laviada, I.6
  • 40
    • 16444375370 scopus 로고    scopus 로고
    • Cannabinoid receptor as a novel target for the treatment of prostate cancer
    • Sarfaraz, S., Afaq, F., Adhami, V.M., and Mukhtar, H. 2005. Cannabinoid receptor as a novel target for the treatment of prostate cancer. Cancer Res. 65:1635-1641.
    • (2005) Cancer Res. , vol.65 , pp. 1635-1641
    • Sarfaraz, S.1    Afaq, F.2    Adhami, V.M.3    Mukhtar, H.4
  • 43
    • 63149127344 scopus 로고    scopus 로고
    • Combined androgen blockade revisited: Emerging options for the treatment of castration-resistant prostate cancer
    • Simmons, M.N., and Klein, E.A. 2009. Combined androgen blockade revisited: Emerging options for the treatment of castration-resistant prostate cancer. Urology 73:697-705.
    • (2009) Urology , vol.73 , pp. 697-705
    • Simmons, M.N.1    Klein, E.A.2
  • 44
    • 42649134105 scopus 로고    scopus 로고
    • Interleukin-21: Basic biology and implications for cancer and autoimmunity
    • Spolski, R., and Leonard, W.J. 2008a. Interleukin-21: Basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 26:57-79.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 57-79
    • Spolski, R.1    Leonard, W.J.2
  • 45
    • 45449104408 scopus 로고    scopus 로고
    • The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer
    • Spolski, R., and Leonard, W.J. 2008b. The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer. Curr. Opin. Immunol. 20:295-301.
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 295-301
    • Spolski, R.1    Leonard, W.J.2
  • 46
    • 36949024039 scopus 로고    scopus 로고
    • Cannabinoids: A new group of agonists of PPARs
    • 23513 [Epub ahead of print]
    • Sun, Y., and Bennett, A. 2007. Cannabinoids: A new group of agonists of PPARs. PPAR Res. 23513 [Epub ahead of print].
    • (2007) PPAR Res.
    • Sun, Y.1    Bennett, A.2
  • 47
    • 33846559718 scopus 로고    scopus 로고
    • Stimulation of epithelial CB1 receptors inhibits contractions of the rat prostate gland
    • Tokanovic, S., Malone, D.T., and Ventura, S. 2007. Stimulation of epithelial CB1 receptors inhibits contractions of the rat prostate gland. Br. J. Pharmacol. 150:227-234.
    • (2007) Br. J. Pharmacol. , vol.150 , pp. 227-234
    • Tokanovic, S.1    Malone, D.T.2    Ventura, S.3
  • 49
    • 16644362550 scopus 로고    scopus 로고
    • Apoptosis in prostate cancer: Progressive and therapeutic implications
    • Wang, G., Reed, E., and Li, Q.Q. 2004. Apoptosis in prostate cancer: Progressive and therapeutic implications. Int. J. Mol. Med. 14:23-34.
    • (2004) Int. J. Mol. Med. , vol.14 , pp. 23-34
    • Wang, G.1    Reed, E.2    Li, Q.Q.3
  • 50
    • 58049196759 scopus 로고    scopus 로고
    • Mechanisms mediating androgen receptor reactivation after castration
    • Yuan, X., and Balk, S.P. 2009. Mechanisms mediating androgen receptor reactivation after castration. Urol. Oncol. 27:36-41.
    • (2009) Urol. Oncol. , vol.27 , pp. 36-41
    • Yuan, X.1    Balk, S.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.