Outcomes of the South African national antiretroviral treatment programme for children: The IeDEA southern Africa collaboration

South African Medical Journal

Volumn 99, Issue 10, 2009, Pages 730-737

  Davies, Mary Ann ^a   Keiser, Olivia ^b   Technau, Karl ^c,d   Eley, Brian ^a   Rabie, Helena ^e   Van Cutsem, Gilles ^a   Giddy, Janet ^f   Wood, Robin ^a   Boulle, Andrew ^a   Egger, Matthias ^b   Moultrie, Harry ^c,d  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^e STELLENBOSCH UNIVERSITY   (South Africa)

^f MCCORD HOSPITAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; EFAVIRENZ; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; STAVUDINE;

ADOLESCENT; ANEMIA; ARTICLE; CD4 LYMPHOCYTE COUNT; CELLULAR IMMUNITY; CHILD; DISEASE SEVERITY; DISEASE TRANSMISSION; FEMALE; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; SOUTH AFRICA; TREATMENT DURATION; VIRUS LOAD; VIRUS TRANSMISSION;

ANTI-RETROVIRAL AGENTS; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; FEMALE; HIV INFECTIONS; HUMANS; INFANT; KAPLAN-MEIERS ESTIMATE; MALE; SEVERITY OF ILLNESS INDEX; SOUTH AFRICA; TREATMENT OUTCOME;

EID: 70450178548     PISSN: 02569574     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. World Health Organization, UNICEF, UNAIDS. Towards Universal Access: scaling up priority HIV/AIDS interventions in the health sector. WHO 2008. http://www.who.int/hiv/mediacentre/2008progressreport/en/index.html (accessed 5 December 2008).
2. National Department of Health SA. Progress report on declaration of commitment on HIV and AIDS. WHO 2008. http://data.unaids.org/pub/Report/2008/ south-africa-2008-country-progress-report-en.pdf (accessed 24 February 2009).
3. World Health Organization. Report of the WHO Technical Reference Group, Paediatric HIV/ ART Care Guideline Meeting. WHO 2008. http://www.who.int/hiv/ pub/meetingreports/art-meeting-april2008/en/index.html (accessed 27 October 2008).
4. Eley B, Davies M-A, Apolles P, et al. Antiretroviral treatment for children. S Afr Med J 2006; 96: 988-993.
5. Jooste JP, Van Zyl AJM, Baker A, Crawford W, Jassen A. Antiretroviral treatment in the Northern Cape. S Afr Med J 2008; 95: 812.
6. Reddi A, Leeper SC, Grobler AC, et al. Preliminary outcomes of a paediatric highly active antiretroviral therapy cohort from KwaZulu-Natal, South Africa. BMC Pediatrics 2007; 7: 13. (Pubitemid 46553973)
7. Sutcliffe CG, van Dijk JH, Bolton C, Persaud D, Moss WJ. Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa. Lancet Infectious Diseases 2008; 8: 477-489. (Pubitemid 352005822)
8. The Kids-ART-LINC Collaboration. Low risk of death, but substantial program attrition, in pediatric treatment cohorts in sub-Saharan Africa. J Aquir Immune Defic Syndr 2008; 15(5): 523-531.
9. Bolton-Moore C, Mubiana-Mbewe M, Cantrell RA, et al. Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia. JAMA 2007; 298(16): 1888-1899. (Pubitemid 350005233)
10. Fassinou P, Elenga N, Rouet F, et al. Highly active antiretroviral therapies among HIV-1-infected children in Abidjan, Cote d'Ivoire. AIDS 2004; 18(14): 1905-1913. (Pubitemid 39313206)
11. Nyandiko WM, Ayaya S, Nabakwe E, et al. Outcomes of HIV-infected orphaned and nonorphaned children on antiretroviral therapy in western Kenya. J Aquir Immune Defic Syndr 2006; 43(4): 418-425. (Pubitemid 44737098)
12. O'Brien DP, Sauvageot D, Zachariah R, Humblet P. In resource-limited settings good early outcomes can be achieved in children using adult fixed-dose combination antiretroviral therapy. AIDS 2006; 20(15): 1955-1960. (Pubitemid 44427613)
13. O'Brien DP, Sauvageot D, Olson D, et al. Treatment outcomes stratified by baseline immunological status among young children receiving nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in resource-limited settings. Clin Infect Dis 2007; 44(9): 1245-1248. (Pubitemid 46651252)
14. Rouet F, Fassinou P, Inwoley A, et al. Long-term survival and immuno-virological response of African HIV-1-infected children to highly active antiretroviral therapy regimens. AIDS 2006; 20(18): 2315-2319. (Pubitemid 44789533)
15. The Malawi Antiretroviral Treatment Group. Antiretroviral therapy for children in the routine setting in Malawi. Transcripts of the Royal Society of Tropical Medicine and Hygiene 2007; 101(5): 511-516.
16. World Health Organization. WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children. WHO 2007. www.who.int/hiv/pub/guidelines/ hivstaging/en/index.html (accessed 28 December 2008).
17. World Health Organization. Interim WHO clinical staging of HIV/AIDS and HIV/AIDS case definitions for surveillance. WHO 2005. www.who.int/hiv/pub/ guidelines/clinicalstaging. pdf (accessed 5 August 2008).
18. World Health Organization. The WHO Child Growth Standards. WHO 2007. http://www.who.int/childgrowth/en/ (accessed 23 November 2008).
19. UNICEF. Definitions. UNICEF 2009. http://www.unicef.org/infobycountry/ stats-popup2.html (accessed 24 February 2009).
20. Judd A, Doerholt K, Tookey PA, et al. Morbidity, mortality, and response to treatment by children in the United Kingdom and Ireland with perinatally acquired HIV infection during 1996-2006: planning for teenage and adult care. Clin Infect Dis 2007; 45(7): 918-924.
21. Van Rossum AMC, Fraaij PLA, De Groot R. Efficacy of highly active antiretroviral therapy in HIV-1 infected children. Lancet Infect Dis 2002; 2: 93-102. (Pubitemid 36114143)
22. Meyers T, Moultrie H, Naidoo K, Cotton M, Eley B, Sherman G. Challenges to pediatric HIV care and treatment in South Africa. J Infect Dis 2007; 196 Suppl 3: S474-S481.
23. Rosen S, Long L, Sanne I. The outcomes and outpatient costs of different models of antiretroviral treatment delivery in South Africa. Trop Med Int Health 2008; 13(8): 1005-1015.
24. Eley B, Nuttall J. Antiretroviral therapy for children: challenges and opportunities. Ann Trop Paediatr 2007; 27: 1-10. (Pubitemid 350010535)
25. Actuarial Society of Southern Africa. Results extracted from the AIDS and Demographic Model of the Actuarial Society of Southern Africa (ASSA). ASSA 2003. http://www.actuarialsociety.org.za (accessed 15 November 2008).
26. Little K, Thorne C, Luo C, et al. Disease progression in children with vertically-acquired HIV infection in sub-Saharan Africa: reviewing the need for HIV treatment. Curr HIV Res 2007; 5(2): 139-153. (Pubitemid 46488193)
27. Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 2008; 359(21): 2233-2244.
28. Mphatswe W, Blanckenberg N, Tudor-Williams G, et al. High frequency of rapid immunological progression in African infants infected in the era of perinatal HIV prophylaxis. AIDS 2007; 19(10): 1253-1261. (Pubitemid 46883479)