Diminished and irregular TSH secretion with delayed acrophase in patients with Cushing's syndrome

European Journal of Endocrinology

Volumn 161, Issue 5, 2009, Pages 695-703

  Roelfsema, Ferdinand ^a   Pereira, Alberto M ^a   Biermasz, Nienke R ^a   Frolich, Marijke ^a   Keenan, Daniel M ^b   Veldhuis, Johannes D ^c   Romijn, Johannes A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF VIRGINIA   (United States)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; GLUCOCORTICOID; HYDROCORTISONE; THYROTROPIN; LIOTHYRONINE; THYROXINE;

ADOLESCENT; ADRENAL CORTEX ADENOMA; ADRENALECTOMY; ADULT; AGED; ARTICLE; BLOOD SAMPLING; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CUSHING SYNDROME; ENTROPY; FEMALE; HISTOPATHOLOGY; HUMAN; HYDROCORTISONE RELEASE; HYPERCORTISOLISM; HYPOPHYSECTOMY; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PULSATILE HORMONE RELEASE; REMISSION; THYROTROPIN RELEASE; TREATMENT OUTCOME; BLOOD; CIRCADIAN RHYTHM; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION; THYROID GLAND; URINE;

ADULT; CIRCADIAN RHYTHM; CUSHING SYNDROME; FEMALE; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MIDDLE AGED; PITUITARY-ADRENAL SYSTEM; THYROID GLAND; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE; YOUNG ADULT;

EID: 70449732264     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-09-0580     Document Type: Article

References (44)

1. Mariotti S. Normal physiology of the hypothalamo-pituitary-thyroidal system and relation to the neural system and other endocrine gland. Chapter 4 in Thyroid Disease Manager, 2006, www.thyroidmanager.org.
2. Faber J, Kirkegaard C, Rasmussen B, Westh H, Busch-Sorensen M & Jensen JW. Pituitary-thyroid axis in critical illness. Journal of Clinical Endocrinology and Metabolism 1987 65 315-320.
3. Adriaanse R, Brabant G, Prank K, Endert E & Wiersinga WM. Circadian changes in pulsatile TSH release in primary hypothyroidism. Clinical Endocrinology 1992 37 504-510.
4. Van den Berghe G, De Zegher F, Veldhuis JD, Wouters P, Gouwy S, Stockman W, Weekers F, Schetz M, Lauwers P, Bouillon R & Bowers CY. Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues. Clinical Endocrinology 1997 47 599-612. (Pubitemid 27496335)
5. Romijn JA, Adriaanse R, Brabant G, Prank K, Endert E & Wiersinga WM. Pulsatile secretion of thyrotropin during fasting: a decrease of thyrotropin pulse amplitude. Journal of Clinical Endocrinology and Metabolism 1999 70 1631-1636.
6. Morley JE. Neuroendocrine control of thyrotropin secretion. Endocrine Reviews 1981 12 396-436.
7. Hollenberg AN. The role the thyrotropin-releasing hormone (TRH) neuron as metabolic sensor. Thyroid 2008 18 131-139.
8. Lechan RM & Fekete C. The TRH neuron: a hypothalamic integrator of energy metabolism. Progress in Brain Research 2006 153 209-235. (Pubitemid 44107417)
9. Brabant G, Brabant A, Ranft U, Ocran K, Kohrle J, Hesch RD & von zur Muhlen A. Circadian and pulsatile thyrotropin secretion in euthyroid man under the influence of thyroid hormone and glucocorticoid administration. Journal of Clinical Endocrinology and Metabolism 1987 65 83-88. (Pubitemid 17092092)
10. Re RN, Kourides IA, Ridgway EC, Weintraub BD & Maloof F. The effect of glucocorticoid administration on human pituitary secretion of thyrotropin and prolactin. Journal of Clinical Endocrinology and Metabolism 1976 43 338-346.
11. Benker G, Raida M, Olbricht T, Wagner R, Reinhardt W & Reinwein D. TSH secretion in Cushing's syndrome: relation to glucocorticoid excess, diabetes, goiter, and the 'sick euthyroid syndrome'. Clinical Endocrinology 1990 33 777-786.
12. Visser TJ & Lamberts SW. Regulation of TSH secretion and thyroid function in Cushing's disease. Acta Endocrinologica 1981 96 480-483.
13. Keenan DM, Roelfsema F, Biermasz N & Veldhuis JD. Physiological control of pituitary hormone secretory-burst mass, frequency, and waveform: a statistical formulation and analysis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 2003 285 R664-R673. (Pubitemid 37040575)
14. Veldhuis JD, Liu PY, Keenan DM, Kok P, Padmanabhan V & O'Byrne K. Sensitivity and specificity of pulse detection using a new deconvolution method. American Journal of Physiology. Endocrinology and Metabolism 2009 297 E538-E544.
15. Pincus SM. Irregularity and asynchrony in biologic network signals. Methods in Enzymology 2000 321 149-182.
16. Veldhuis JD, Straume M, Iranmanesh A, Mulligan T, Jaffe C, Barkan A, Johnson ML & Pincus S. Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 2001 280 R721-R729. (Pubitemid 32494075)
17. Keenan DM & Veldhuis JD. Hypothesis testing of the aging male gonadal axis via a biomathematical construct. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 2001 280 R1755-R1771. (Pubitemid 32552464)
18. Liu PY, Pincus SM, Keenan DM, Roelfsema F & Veldhuis JD. Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 2005 288 R440-R446. (Pubitemid 40129611)
19. Adriaanse R, Brabant G, Endert E & Wiersinga WM. Pulsatile thyrotropin secretion in patients with Cushing's syndrome. Metabolism 1994 43 782-786. (Pubitemid 24181209)
20. Samuels MH & McDaniel PA. Thyrotropin levels during hydrocortisone infusions that mimic fasting-induced cortisol elevations: a clinical research center study. Journal of Clinical Endocrinology and Metabolism 1997 82 3700-3704.
21. Saane LM, Carro E, Tovar S, Casanueva FF & Dieguez C. Regulation of in vivo TSH secretion by leptin. Regulatory Peptides 2000 92 25-29. (Pubitemid 30748546)
22. Lewis BM, Dieguez C, Lewis MD & Scanlon MF. Dopamine stimulates release of thyrotrophin-releasing hormone from perfused intact rat hypothalamus via hypothalamic D2-receptors. Journal of Endocrinology 1987 115 419-424. (Pubitemid 18003079)
23. Ahlquist JA, Franklyn JA, Ramsden DB & Sheppard MC. The influence of dexamethasone on serum thyrotrophin and thyrotrophin synthesis in the rat. Molecular and Cellular Endocrinology 1989 64 55-61. (Pubitemid 19138276)
24. John CD, Christian HC, Morris JF, Flower RJ, Solito E & Buckingham JC. Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides. Journal of Neuroendocrinology 2003 15 946-957. (Pubitemid 37193011)
25. Taylor AD, Flower RJ & Buckingham JC. Dexamethasone inhibits the release of TSH from the rat anterior pituitary gland in vitro mechanisms dependent on de novo protein synthesis and lipocortin 1. Journal of Endocrinology 1995 147 533-544.
26. Taylor AD, Philip JG, John CD, Cover PO, Morris JF, Flower RJ & Buckingham JC. Annexin 1 (lipocortin 1) mediates the glucocorticoid inhibition of cyclic adenosine 3′,5′-monophosphate - stimulated prolactin secretion. Journal of Clinical Endocrinology and Metabolism 2000 141 2209-2219.
27. Traverso V, Christian HC, Morris JF & Buckingham JC. Lipocortin 1 (annexin 1): a candidate paracrine agent localized in pituitary folliculo-stellate cells. Endocrinology 1999 140 4311-4319. (Pubitemid 30647130)
28. Hofland LJ & Lamberts SW. Somatostatin receptor in pituitary function, diagnosis and therapy. Frontiers of Hormone Research 2004 32 235-252.
29. Estupina C, Abarca J, Arancibia S & Belmar J. N-methyl-D-aspartate receptor involvement in dexamethasone and stressinduced hypothalamic somatostatin release in rats. Neuroscience Letters 1996 219 203-206. (Pubitemid 26405568)
30. Estupina C, Belmar J, Tapia-Arancibia L, Astier H & Arancidia S. Rapid and opposite effects of dexamethasone on in vivo and in vitro hypothalamic somatostatin release. Experimental Brain Research 1997 113 337-342. (Pubitemid 27090855)
31. Nakagawa K, Ishizuka T, Shimizu C, Ito Y & Wakabayashi I. Increased hypothalamic somatostatin mRNA following dexamethasone administration in rats. Acta Endocrinologica 1992 127 416-419.
32. Cintra A, Fuxe K,Wikstrom AC, Visser T & Gustafsson JA. Evidence for thyrotropin-releasing hormone and glucorticoid receptor-immunoreactive neurons in various preoptic and hypothalamic nuclei of the male rat. Brain Research 1990 506 139-144. (Pubitemid 20020086)
33. Kakucska I, Yanping QI & Lechan RM. Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone. Endocrinology 1995 136 2795-2802.
34. Perez-Martinez L, Carreon-Rodriguez A, Elena Gonzalez-Alzati M, Morales C, Charli JL & Bravo PJ. Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cultures: interaction with the cAMP pathway. Neuroendocrinology 1998 68 345-354. (Pubitemid 28526312)
35. Mitsuma T & Nogimori T. Effects of dexamethasone on the hypothalamic-pituitary-thyroid axis in rats. Acta Endocrinologica 1982 100 51-56. (Pubitemid 12075404)
36. Szabo M & Frohman LA. Suppression of cold-stimulated thyrotropin secretion by antiserum to thyrotropin-releasing hormone. Endocrinology 1997 101 1023-1033.
37. Chopra IJ, Williams DE, Orgiazzi J & Solomon DH. Opposite effects of dexamethasone on serum concentrations of 3,30,50-triiodothyronine (reverse T3) and 3,30,5-triiodothyronine (T3). Journal of Clinical Endocrinology and Metabolism 1975 41 911-920.
38. Pazos-Moura CC, Ortiga-Cavalho TM & Gaspar de Moura E. The autocrine/paracrine regulation of thyrotropin secretion. Thyroid 2003 13 167-175.
39. Bianco AC & Kim BW. Deiodinases: implications of the local control of thyroid hormone action. Journal of Clinical Investigation 2006 116 2571-2579.
40. Biermasz NR, Smit JW, Pereira AM, Frolich M, Romijn JA & Roelfsema F. Acromegaly caused by growth hormone-releasing hormone-producing tumors: long-term observational studies in three patients. Pituitary 2007 10 237-249. (Pubitemid 350055035)
41. Roelfsema F, Pincus SM & Veldhuis JD. Patients with Cushing's disease secrete adrenocorticotropin and cortisol jointly more asynchronously than healthy subjects. Journal of Clinical Endocrinology and Metabolism 1998 83 688-692. (Pubitemid 28496559)
42. Roelfsema F, Biermasz NR, Frolich M, Keenan DM, Veldhuis JD & Romijn JA. Diminished and irregular thyrotropin secretion with preserved diurnal rhythm in patients with active acromegaly. Journal of Clinical Endocrinology and Metabolism 2009 94 1945-1950.
43. Hangaard J, Andersen M, Grodum E, Koldjaer O & Hagen C. Pulsatile thyrotropin secretion in patients with Addison's disease during variable glucocorticoid therapy. Journal of Clinical Endocrinology and Metabolism 1996 81 2502-2507. (Pubitemid 26240267)
44. Persani L. Hypothalamic thyrotropin-releasing hormone and thyrotropin biological activity. Thyroid 1998 8 941-946. (Pubitemid 28514188)