Patients with Cushing's disease secrete adrenocorticotropin and cortisol jointly more asynchronously than healthy subjects

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 2, 1998, Pages 688-692

  Roelfsema, Ferdinand ^a   Pincus, Steven M ^c   Veldhuis, Johannes D ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NATIONAL SCIENCE FOUNDATION   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE;

ADOLESCENT; ADRENAL TUMOR; ADULT; AGED; CLINICAL ARTICLE; CORTICOTROPIN RELEASE; CUSHING DISEASE; ENTROPY; FEEDBACK SYSTEM; HUMAN; HYDROCORTISONE RELEASE; MALE; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; STATISTICAL ANALYSIS;

ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; AGED; AGING; CUSHING SYNDROME; FEEDBACK; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; PERIODICITY;

EID: 0031791252     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.2.688     Document Type: Review

References (16)

1. Pincus SM. 1991 Approximate entropy as a measure of system complexity. Proc Natl Acad Sciences USA. 88:2297-2301.
2. Pincus SM, Huang WM. 1992 Approximate entropy: statistical properties and applications. Commun Statis-Theory Meth. 21:3061-3077.
3. Pincus SM, Goldberger AL. 1994 Physiological time-series analysis: what does regularity quantify? Am J Physiol. 266: H1643-H1656.
4. Van den Berg G, Pincus SM, Veldhuis JD, Frölich M, Roelfsema F. 1997 Greater disorderliness of ACTH and cortisol release accompanies pituitary-dependent Cushing's disease. Eur J Endocrinol. 136:394-400.
5. Hartman ML, Pincus SM, Johnson ML, et al. 1994 Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release. J Clin Invest. 94:1277-1288.
6. Siragy HM, Vieweg WVR, Pincus SM, Veldhuis JD. 1995 Increased disorderliness and amplified basal and pulsatile aldosterone secretion in patients with primary aldosteronism. J Clin Endocrinol Metab. 80:28-33.
7. Schmitz O, Porksen N, Nyholm B, et al. 1997 Disorderly and nonstationary insulin secretion in relatives of patients with non-insulin-dependent diabetes mellitus. Am J Physiol. 272:E218-E224.
8. Pincus SM, Singer BH. 1996 Randomness and degrees of irregularity. Proc Natl Acad Sciences USA. 93:2083-2088.
9. Pincus SM, Mulligan T, Iranmanesh A, Gheorghiu S, Godschalk M, Veldhuis JD. 1996 Older males secrete luteinizing hormone (LH) and testosterone more irregularly, and jointly more asynchronously, than younger males. Proc Natl Acad Sci USA. 93:14100-14105.
10. Biemond P, de Jong FH, Lamberts SWJ. 1990 Continuous dexamethasone infusion for seven hours in patients with the Cushing syndrome. Ann Int Med. 112:738-742.
11. Veldhuis JD, Johnson ML. 1992 Deconvolution analysis of hormone data. Methods in Enzymology. 210:539-575.
12. Roelfsema F, van den Berg C, Frölich M, et al. 1993 Sex-dependent alteration in cortisol response to endogenous adrenocorticotropin. J Clin Endocrinol Metab. 77:234-240.
13. Veldhuis JD, Moorman J, Johnson ML. 1994 Deconvolution analysis of neuroendocrine data:waveform-independent methods and applications. Methods in Neurosciences. 20:279-325.
14. Van den Berg G, Frölich M, Veldhuis JD, Roelfsema F. 1995 Combined amplification of the pulsatile and basal modes of adrenocorticotropin and cortisol secretion in patients with Cushing's disease: evidence for decreased responsiveness of the adrenal gland. J Clin Endocrinol Metab. 80:3750-3757.
15. Veldhuis JD, Johnson ML, Seneta E. 1991 Analysis of the copulsatility of anterior pituitary hormones. J Clin Endocrinol Metab. 73:569-576.
16. Veldhuis JD, Johnson ML. 1986 Cluster analysis: a simple, versatile and robust algorithm for endocrine pulse detection. Am J Physiol. 250:E486-E493.