메뉴 건너뛰기




Volumn 15, Issue 33, 2009, Pages 4143-4149

Molecular determinants of the profibrogenic effects of endothelin-1 in pancreatic stellate cells

Author keywords

Chronic pancreatitis; Endothelin 1; Fibrosis; Pancreatic stellate cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYTOKINE; ENDOTHELIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD3 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 70449730492     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.15.4143     Document Type: Article
Times cited : (11)

References (29)
  • 5
    • 33845998896 scopus 로고    scopus 로고
    • The pancreatic stellate cell: A star on the rise in pancreatic diseases
    • Omary MB, Lugea A, Lowe AW, Pandol SJ. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J Clin Invest 2007; 117: 50-59
    • (2007) J Clin Invest , vol.117 , pp. 50-59
    • Omary, M.B.1    Lugea, A.2    Lowe, A.W.3    Pandol, S.J.4
  • 6
    • 0033969266 scopus 로고    scopus 로고
    • Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: Implications in pathogenesis of pancreas fibrosis
    • Luttenberger T, Schmid-Kotsas A, Menke A, Siech M, Beger H, Adler G, Grunert A, Bachem MG. Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: implications in pathogenesis of pancreas fibrosis. Lab Invest 2000; 80: 47-55
    • (2000) Lab Invest , vol.80 , pp. 47-55
    • Luttenberger, T.1    Schmid-Kotsas, A.2    Menke, A.3    Siech, M.4    Beger, H.5    Adler, G.6    Grunert, A.7    Bachem, M.G.8
  • 8
    • 0036282292 scopus 로고    scopus 로고
    • Pancreatic stellate cells respond to inflammatory cytokines: Potential role in chronic pancreatitis
    • Mews P, Phillips P, Fahmy R, Korsten M, Pirola R, Wilson J, Apte M. Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 2002; 50: 535-541
    • (2002) Gut , vol.50 , pp. 535-541
    • Mews, P.1    Phillips, P.2    Fahmy, R.3    Korsten, M.4    Pirola, R.5    Wilson, J.6    Apte, M.7
  • 10
    • 14844292619 scopus 로고    scopus 로고
    • Role of endothelin in fibrosis and anti-fibrotic potential of bosentan
    • DOI 10.1080/07853890410018925
    • Clozel M, Salloukh H. Role of endothelin in fibrosis and anti-fibrotic potential of bosentan. Ann Med 2005; 37: 2-12 (Pubitemid 40347290)
    • (2005) Annals of Medicine , vol.37 , Issue.1 , pp. 2-12
    • Clozel, M.1    Salloukh, H.2
  • 11
    • 59449106165 scopus 로고    scopus 로고
    • Synergistic growth inhibitory effects of the dual endothelin-1 receptor antagonist bosentan on pancreatic stellate and cancer cells
    • Fitzner B, Brock P, Holzhuter SA, Nizze H, Sparmann G, Emmrich J, Liebe S, Jaster R. Synergistic growth inhibitory effects of the dual endothelin-1 receptor antagonist bosentan on pancreatic stellate and cancer cells. Dig Dis Sci 2009; 54: 309-320
    • (2009) Dig Dis Sci , vol.54 , pp. 309-320
    • Fitzner, B.1    Brock, P.2    Holzhuter, S.A.3    Nizze, H.4    Sparmann, G.5    Emmrich, J.6    Liebe, S.7    Jaster, R.8
  • 12
    • 0038121640 scopus 로고    scopus 로고
    • Production and effects of endothelin-1 in rat pancreatic stellate cells
    • DOI 10.1097/00006676-200307000-00010
    • Klonowski-Stumpe H, Reinehr R, Fischer R, Warskulat U, Luthen R, Haussinger D. Production and effects of endothelin-1 in rat pancreatic stellate cells. Pancreas 2003; 27: 67-74 (Pubitemid 36775981)
    • (2003) Pancreas , vol.27 , Issue.1 , pp. 67-74
    • Klonowski-Stumpe, H.1    Reinehr, R.2    Fischer, R.3    Warskulat, U.4    Luthen, R.5    Haussinger, D.6
  • 14
    • 0036785330 scopus 로고    scopus 로고
    • Extracellular signal regulated kinases are key mediators of mitogenic signals in rat pancreatic stellate cells
    • Jaster R, Sparmann G, Emmrich J, Liebe S. Extracellular signal regulated kinases are key mediators of mitogenic signals in rat pancreatic stellate cells. Gut 2002; 51: 579-584
    • (2002) Gut , vol.51 , pp. 579-584
    • Jaster, R.1    Sparmann, G.2    Emmrich, J.3    Liebe, S.4
  • 16
    • 0028955316 scopus 로고
    • Characterization and functional analysis of the rat endothelin-1 promoter
    • Paul M, Zintz M, Bocker W, Dyer M. Characterization and functional analysis of the rat endothelin-1 promoter. Hypertension 1995; 25: 683-693
    • (1995) Hypertension , vol.25 , pp. 683-693
    • Paul, M.1    Zintz, M.2    Bocker, W.3    Dyer, M.4
  • 17
    • 0038801663 scopus 로고    scopus 로고
    • Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-β - Mediated induction of endothelin-1 expression
    • DOI 10.1161/01.RES.0000078491.79697.7F
    • Rodriguez-Pascual F, Redondo-Horcajo M, Lamas S. Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-betamediated induction of endothelin-1 expression. Circ Res 2003; 92: 1288-1295 (Pubitemid 36773470)
    • (2003) Circulation Research , vol.92 , Issue.12 , pp. 1288-1295
    • Rodriguez-Pascual, F.1    Redondo-Horcajo, M.2    Lamas, S.3
  • 22
    • 17144404527 scopus 로고    scopus 로고
    • Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
    • DOI 10.1053/j.gastro.2004.12.036
    • Bachem MG, Schunemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, Adler G. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 2005; 128: 907-921 (Pubitemid 40523543)
    • (2005) Gastroenterology , vol.128 , Issue.4 , pp. 907-921
    • Bachem, M.G.1    Schunemann, M.2    Ramadani, M.3    Siech, M.4    Beger, H.5    Buck, A.6    Zhou, S.7    Schmid-Kotsas, A.8    Adler, G.9
  • 24
    • 10744221950 scopus 로고    scopus 로고
    • Tumor Stroma Interactions Induce Chemoresistance in Pancreatic Ductal Carcinoma Cells Involving Increased Secretion and Paracrine Effects of Nitric Oxide and Interleukin-1β
    • DOI 10.1158/0008-5472.CAN-03-1860
    • Muerkoster S, Wegehenkel K, Arlt A, Witt M, Sipos B, Kruse ML, Sebens T, Kloppel G, Kalthoff H, Folsch UR, Schafer H. Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res 2004; 64: 1331-1337 (Pubitemid 38235601)
    • (2004) Cancer Research , vol.64 , Issue.4 , pp. 1331-1337
    • Muerkoster, S.1    Wegehenkel, K.2    Arlt, A.3    Witt, M.4    Sipos, B.5    Kruse, M.-L.6    Sebens, T.7    Kloppel, G.8    Kalthoff, H.9    Folsch, U.R.10    Schafer, H.11
  • 26
    • 0026509439 scopus 로고
    • Transcriptional regulation of the endothelin-1 gene by TNF-alpha
    • Marsden PA, Brenner BM. Transcriptional regulation of the endothelin-1 gene by TNF-alpha. Am J Physiol 1992; 262: C854-C861
    • (1992) Am J Physiol , vol.262
    • Marsden, P.A.1    Brenner, B.M.2
  • 28
    • 33847176982 scopus 로고    scopus 로고
    • Inhibitory effects of interferon-γ on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression
    • DOI 10.1016/j.cellsig.2006.10.002, PII S0898656806002725
    • Fitzner B, Brock P, Nechutova H, Glass A, Karopka T, Koczan D, Thiesen HJ, Sparmann G, Emmrich J, Liebe S, Jaster R. Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression. Cell Signal 2007; 19: 782-790 (Pubitemid 46298801)
    • (2007) Cellular Signalling , vol.19 , Issue.4 , pp. 782-790
    • Fitzner, B.1    Brock, P.2    Nechutova, H.3    Glass, A.4    Karopka, T.5    Koczan, D.6    Thiesen, H.-J.7    Sparmann, G.8    Emmrich, J.9    Liebe, S.10    Jaster, R.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.