Halitosis: A review of associated factors and therapeutic approach

Brazilian Oral Research

Volumn 22, Issue SUPPL.1, 2008, Pages 44-54

  Cortelli, José Roberto ^a   Barbosa, Mônica Dourado Silva ^b   Westphal, Miriam Ardigó ^c  

^a UNIVERSITY OF TAUBATÉ   (Brazil)

^b Foundation for Development of the Sciences   (Brazil)

^c FEDERAL UNIVERSITY OF AMAZONAS   (Brazil)

Author keywords

Halitosis diagnosis; Halitosis epidemiology; Halitosis etiology; Halitosis therapy; Mouthrinses therapeutic use

Indexed keywords

HALITOSIS; HEALTH; HUMAN; MICROBIOLOGY; MOUTH; MOUTH HYGIENE; PREVALENCE; REVIEW;

HALITOSIS; HUMANS; MOUTH; ORAL HEALTH; ORAL HYGIENE; PREVALENCE;

EID: 70449730272     PISSN: 18068324     EISSN: 18073107     Source Type: Journal    
DOI: 10.1590/S1806-83242008000500007     Document Type: Article

References (64)

1. van den Broek AM, Feenstra L, de Baat C. A review of the current literature on management of halitosis. Oral Dis. 2008;14(1):30-9. Review 2.
2. Rosenberg M. Bad breath and periodontal disease: how related are they? J Clin Periodontol. 2006;33(1):29-30.
3. Sanz M, Roldán S, Herrera D. Fundamentals of Breath Malodour. J Contemp Dent Pract. 2001 Nov 15;2(4):1-17.
4. Bosy A. Oral malodor: philosophical and practical aspects. J Can Dent Assoc. 1997;63(3):196-201. Review 5.
5. Greenman J, Duffield J, Spencer P, Rosenberg M, Corry D, Saad S et al. Study on the organoleptic intensity scale for measuring oral malodor. J Dent Res. 2004;83(1):81-5.
6. Ayers KMS, Colquhoun AUK. Halitosis: causes, diagnosis, and treatment. New Zeal Dent J. 1998;94:156-60.
7. Awano S, Gohara K, Kurihara E, Ansai T, Takehara T. The relationship between the presence of periodontopathogenic bacteria in saliva and halitosis. Int Dent J. 2002;52 Suppl 3:212-6.
8. Porter SR, Scully C. Oral malodour (halitosis). BMJ. 2006;23;333(7569):632-5. Review.
9. Goldberg S, Kozlovsky A, Gordon D, Gelernter I, Sintov A, Rosenberg M. Cadaverine as a putative component of oral malodor. J Dent Res. 1994;73(6):1168-72.
10. Tonzetich J. Production and origin of oral malodor: a review of mechanisms and methods of analysis. J Periodontol. 1977;48(1):13-20.
11. Quirynen M, Zhao H, Soers C, Dekeyser C, Pauwels M, Coucke W et al. The impact of periodontal therapy and the adjunctive effect of antiseptics on breath odor-related outcome variables: a double-blind randomized study. J Periodontol. 2005;76(5):705-12.
12. Donaldson A, McKenzie D, Riggio M, Hodge P, Rolph H, Flanagan A et al. Microbiological culture analysis of the tongue anaerobic microflora in subjects with and without halitosis. Oral Dis. 2005;11 Suppl 1:61-3.
13. Riggio MP, Lennon A, Rolph HJ, Hodge PJ, Donaldson A, Maxwell AJ et al. Molecular identification of bacteria on the tongue dorsum of subjects with and without halitosis. Oral Dis. 2008;14(3):251-8.
14. Rosenberg M. Bad breath: research perspectives. Ramat Aviv: Ramot Publishing-Tel Aviv University Press; 1997.
15. Newman MG. The role of periodontitis in oral malodour: clinical perspectives. In: van Steenberghe D, Rosenberg M, eds. Bad Breath: A multidisciplinary approach. Leuven: Leuven University Press; 1996. p. 3-14.
16. Lee SS, Zhang W, Li Y. Halitosis update: a review of causes, diagnoses, and treatments. J Calif Dent Assoc. 2007;35(4):258-60, 262, 264-8. Review.
17. Miyazaki H, Sakao S, Katoh Y, Takehara T. Correlation between volatile sulphur compounds and certain oral health measurements in the general population. J Periodontol. 1995;66(8):679-84.
18. Liu XN, Shinada K, Chen XC, Zhang BX, Yaegaki K, Kawaguchi Y. Oral malodor-related parameters in the Chinese general population. J Clin Periodontol. 2006;33:31-6.
19. Al-Ansari JM, Boodai H, Al-Sumait N, Al-Khabbaz AK, Al-Shammari KF, Salako N. Factors associated with self-reported halitosis in Kuwaiti patients. J Dent. 2006;34(7):444-9.
20. Yaegaki K, Coil JM. Examination, Classification, and Treatment of Halitosis; Clinical Perspectives. J Can Dent Assoc. 2000;66:257-6. Review.
21. Lee PP, Mak WY, Newsome P. The aetiology and treatment of oral halitosis: an update. Hong Kong Med J. 2004;10(6):414-8.
22. Miyazaki H, Arao M, Okamura K, Kawaguchi Y, Toyofuku A, Hoshi K et al. [Tentative classification of halitosis and its treatment needs] [Article in Japanese]. Niigata Dent J. 1999;32:7-11.
23. Morita M, Wang HL. Relationship between sulcular sulfide level and oral malodor in subjects with periodontal disease. J Periodontol. 2001;72(1):79-84.
24. Tanaka M, Yamamoto Y, Kuboniwa M, Nonaka A, Nishida N, Maeda K et al. Contribution of periodontal pathogens on tongue dorsa analyzed with real-time PCR to oral malodor. Microbes Infect. 2004;6(12):1078-83.
25. Peruzzo DC, Jandiroba PFCB, Nogueira Filho GR. Use of 0.1% chlorine dioxide to inhibit the formation of morning volatile sulphur compounds (VSC). Braz Oral Res. 2007;21(1):70-4.
26. Ueno M, Shinada K, Yanagisawa T, Mori C, Yokoyama S, Furukawa S et al. Clinical oral malodor measurement with a portable sulfide monitor. Oral Dis. 2008;14:264-9.
27. Quirynen M, Zhao H, van Steenberghe D. Review of the treatment strategies for oral malodour. Clin Oral Investig. Mar;6(1):1-10. Review.
28. Yaegaki K, Sanada K. Volatile sulfur compounds in mouth air from clinically healthy subjects and patients with periodontal disease. J Periodontal Res. 1992;27:233-8.
29. Roldán S, Winkel EG, Herrera D, Sanz M, Van WinkelhoffAJ. The effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc lactate on the microflora of oral halitosis patients: a dual-centre, double-blind placebocontrolled study. J Clin Periodontol. 2003;30(5):427-34.
30. Roldán S, Herrera D, O'Connor A, González I, Sanz M. A combined therapeutic approach to manage oral halitosis: a 3-month prospective case series. J Periodontol. 2005;76(6):1025-33.
31. Farrell S, Baker RA, Somogyi-Mann M, Witt JJ, Gerlach RW. Oral malodor reduction by a combination of chemotherapeutical and mechanical treatments. Clin Oral Investig. 2006;10(2):157-63.
32. Faveri M, Hayacibara MF, Pupio GC, Cury JA, Tsuzuki CO, Hayacibara RM. A cross-over study on the effect of various therapeutic approaches to morning breath odour. J Clin Periodontol. 2006;33(8):555-60.
33. Roldán S, Herrera D, Sanz M. Biofilms and the tongue: therapeutical approaches for the control of halitosis. Clin Oral Investig. 2003;7:189-97.
34. Krespi YP, Shrime MG, Kacker A. The relationship between oral malodor and volatile sulfur compound-producing bacteria. Otolaryngol Head Neck Surg. 2006;135(5):671-6.
35. De Boever EH, Uzeda M, Loesche WJ. Role of tongue surface characteristics and tongue flora in halitosis. J Dent Res. 1995;74:127.
36. Mantilla Gómez S, Danser MM, Sipos PM, Rowshani B, van der Velden U, van der Weijden GA. Tongue coating and salivary bacterial counts in healthy/gingivitis subjects and periodontitis patients. J Clin Periodontol. 2001;28:970-8.
37. Loesche WJ, Kazor C. Microbiology and treatment of halitosis. Periodontol 2000. 2002;28:256-79.
38. Yaegaki K, Coil JM, Kamemizu T, Miyazaki H. Tongue brushing and mouth rinsing as basic treatment measures for halitosis. Int Dent J. 2002;52 Suppl 3:192-6.
39. Kaizu T, Tsunoda M, Aoki H, Kimura K. Analysis of volatile sulphur compounds in mouth air by gas chromatography. Bull Tokyo Dent Coll. 1978;19:43-52.
40. Suarez FL, Furne, JK, Springfield J, Levitt MD. Morning breath odor: influence of treatments on sulfur gases. J Dent Res. 2000;79:1773-7.
41. Seemann R, Kison A, Mozhgan B, Zimmer S. Effectiveness of mechanical tongue cleaning on oral levels of volatile sulfur compounds. J Am Dent Assoc. 2001;132:1263-7.
42. Kleinberg I, Codipilly DM. Cystein challenge testing: a powerful tool for examining oral malodour process and treatments in vivo. Int Dent J. 2002;52(3):221-8.
43. Quirynen M, Avontroodt P, Soers C, Zhao H, Pauwels M, Steenberghe D. Impact of tongue cleansers on microbial load and taste. J Clin Periodontol. 2004;31(7):506-10.
44. Tanaka M, Anguri H, Nishida N, Ojima M, Nagata H, Shizukuishi S. Reliability of clinical parameters for predicting the outcome of oral malodor treatment. J Dent Res. 2003;82:518-22.
45. Yaegaki K, Sanada K. Biochemical and clinical factors influencing oral malodor in periodontal patients. J Periodontol. 1992;63:783-9.
46. Tsai CC, Chou HH, Wu TL, Yang YH, Ho KY, Wu YM et al. The levels of volatile sulfur compounds in mouth air from patients with chronic periodontitis. J Periodontal Res. 2008;43:186-93.
47. Bosy A, Kulkarni GV, Rosenberg M, McCulloch CA. Relationship of oral malodor to periodontitis: evidence of independence in discrete subpopulations. J Periodontol. 1994;65(1):37-46.
48. De Boever EH, Loesche WJ. Assessing the contribution of anaerobic microflora of the tongue to oral malodor. J Am Dent Assoc. 1995;126(10):1384-93.
49. van Steenberghe D, Avontroodt P, Peeters W, Pauwels M, Coucke W, Lijnen A et al. Effect of different mouthrinses on morning breath. J Periodontol. 2001;72(9):1183-91.
50. Carvalho MD, Tabchoury CM, Cury JA, Toledo S, Nogueira-Filho GR. Impact of mouthrinses on morning bad breath in healthy subjects. J Clin Peridontol. 2004;31:85-90.
51. Young A, Jonski G, Rölla G. Inhibition of orally produced volatile sulfur compounds by zinc, chlorhexidine or cetylpyridinium chloride-effect of concentration. Eur J Oral Sci. 2003;111:400-4.
52. Gunsolley JC. A meta-analysis of six-month studies of antiplaque and antigingivitis agents. J Am Dent Assoc. 2006 Dec;137(12):1649-57. Review.
53. Pitts G, Brogdon C, Hu L, Masurat T, Pianotti R, Schumann P. Mechanism of action of an antiseptic, anti-odor mouthwash. J Dent Res. 1983;62(6):738-42.
54. Fine DH, Furgang D, Sinatra K, Charles C, McGuire A, Kumar LD. In vivo antimicrobial effectiveness of an essential oil-containing mouth rinse 12 h after a single use and 14 days' use. J Clin Periodontol. 2005;32:335-40.
55. Young A, Jonski G, Rölla G. A study of triclosan and its solubilizers as inhibitors of oral malodour. J Clin Periodontol. 2002;29:1078-81.
56. Moran J, Addy M. The effects of a cetylpyridinium chloride prebrushing rinse as an adjunct to oral hygiene and gingival health. J Periodontol. 1991;62:562-4.
57. Roberts WR, Addy M. Comparison of the in vivo and in vitro antibacterial properties of antiseptic mouthrinses containing chlorhexidine, alexidine, cetyl pyridinium chloride and hexetidine. Relevance to mode of action. J Clin Periodontol. 1981;8:295-310.
58. Ng W, Tonzetich J. Effect of hydrogen sulphide and methyl mercaptan on the permeability of oral mucosa J Dent Res. 1984;63:994-7.
59. Quirynen M, Avontroodt P, Soers C, Zhao H, Pauwels M, Coucke W et al. The efficacy of amine fluoride/stannous fluoride in the suppression of morning breath odour. J Clin Periodontol. 2002;29:944-54.
60. Young A, Jonski G, Rölla G, Wåler SM. Effects of metal salts on the oral production of volatile sulfur-containing compounds (VSC). J Clin Periodontol. 2001;28:776-81.
61. Frascella J, Gilbert R, Fernandez P. Odour reduction potential of a chlorine dioxide mouthrinse. J Clin Dent. 1998;9(2):39-42.
62. Richter JL. Diagnosis and treatment of halitosis. Compendium Contin Educ Dent. 1996;17:370-2, 374-6 passim; quiz 388.
63. Winkel EG, Roldán S, Van WinkelhoffAJ, Herrera D, Sanz M. Clinical effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc-lactate on oral halitosis. A dual-center, double-blind placebo-controlled study. J Clin Periodontol. 2003;30:300-6.
64. Roldán S, Herrera D, Santa-Cruz I, O'Connor A, González I, Sanz M. Comparative effects of different chlorhexidine mouth-rinse formulations on volatile sulphur compounds and salivary bacterial counts. J Clin Periodontol. 2004;31:1128-34.