3′UTR mediated regulation of the cyclin D1 proto-oncogene

Cell Cycle

Volumn 8, Issue 21, 2009, Pages 3592-3600

  Deshpande, Anagha ^a,b   Pastore, Alessandro ^a,b   Deshpande, Aniruddha J ^a,b,c   Zimmermann, Yvonne ^a,b   Hutter, Grit ^a,b   Weinkauf, Marc ^a,b   Buske, Christian ^a,b   Hiddemann, Wolfgang ^a,b   Dreyling, Martin ^a,b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Clinical Cooperation Group Antigen specific Immunotherapy   (Germany)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

AU rich elements; Cell cycle; Cyclin D1; MCL; MicroRNA

Indexed keywords

CYCLIN D1; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; MESSENGER RNA; MICRORNA;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CANCER CELL; CELL ISOLATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GENE DELETION; GENE EXPRESSION REGULATION; GENE LOSS; HUMAN; HUMAN CELL; MANTLE CELL LYMPHOMA; MOUSE; NONHUMAN; PHENOTYPE; POINT MUTATION; PROTO ONCOGENE; REPORTER GENE; UPREGULATION;

EID: 70449728473     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.21.9993     Document Type: Article

References (35)

1. Hall M, Peters G. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv Cancer Res 1996; 68:67-108. (Pubitemid 26099813)
2. Motokura T, Arnold A. Cyclin D and oncogenesis. Curr Opin Genet Dev 1993; 3:5-10.
3. Sherr CJ. Cancer cell cycles. Science 1996; 274:1672-1677
4. Arnold A, Motokura T, Bloom T, Rosenberg C, Bale A, Kronenberg H, et al. PRAD1 (cyclin D1): a parathyroid neoplasia gene on 11q13. Henry Ford Hosp Med J 1992; 40:177-180
5. Rosenberg CL, Wong E, Petty EM, Bale AE, Tsujimoto Y, Harris NL, Arnold A. PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma. Proc Natl Acad Sci USA 1991; 88:9638-9642
6. Withers DA, Harvey RC, Faust JB, Melnyk O, Carey K, Meeker TC. Characterization of a candidate bcl-1 gene. Mol Cell Biol 1991; 11:4846-4853
7. Williams ME, Swerdlow SH, Rosenberg CL, Arnold A. Chromosome 11 translocation breakpoints at the PRAD1/cyclin D1 gene locus in centrocytic lymphoma. Leukemia 1993; 7:241-245 (Pubitemid 23079234)
8. Callender T, el-Naggar AK, Lee MS, Frankenthaler R, Luna MA, Batsakis JG. PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma. Cancer 1994; 74:152-158
9. Fujisawa H, Misaki K, Takabatake Y, Hasegawa M, Yamashita J. Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation. J Neurooncol 2005; 73:117-124 (Pubitemid 40974031)
10. Sutherland RL, Musgrove EA. Cyclins and breast cancer. J Mammary Gland Biol Neoplasia 2004; 9:95-104.
11. Buckley MF, Sweeney KJ, Hamilton JA, Sini RL, Manning DL, Nicholson RI, et al. Expression and amplification of cyclin genes in human breast cancer. Oncogene 1993; 8:2127-2133
12. Bartkova J, Lukas J, Muller H, Lutzhoft D, Strauss M, Bartek J. Cyclin D1 protein expression and function in human breast cancer. Int J Cancer 1994; 57:353-361 (Pubitemid 24168609)
13. Hosokawa Y, Arnold A. Mechanism of cyclin D1 (CCND1, PRAD1) overexpression in human cancer cells: analysis of allele-specific expression. Genes Chromosomes Cancer 1998; 22:66-71. (Pubitemid 28217808)
14. Lebwohl DE, Muise-Helmericks R, Sepp-Lorenzino L, Serve S, Timaul M, Bol R, et al. A truncated cyclin D1 gene encodes a stable mRNA in a human breast cancer cell line. Oncogene 1994; 9:1925-1929 (Pubitemid 24194159)
15. Molenaar JJ, van Sluis P, Boon K, Versteeg R, Caron HN. Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma. Genes Chromosomes Cancer 2003; 36:242-249 (Pubitemid 36158197)
16. Wiestner A, Tehrani M, Chiorazzi M, Wright G, Gibellini F, Nakayama K, et al, for the Lymphoma/Leukemia Molecular Profiling P. Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival. Blood 2007; 109:4599-4606
17. Jares P, Colomer D, Campo E. Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer 2007; 7:750-762 (Pubitemid 47463673)
18. Sander B, Flygare J, Porwit-Macdonald A, Smith CI, Emanuelsson E, Kimby E, et al. Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1. Int J Cancer 2005; 117:418-430 (Pubitemid 41429565)
19. Rimokh R, Berger F, Bastard C, Klein B, French M, Archimbaud E, et al. Rearrangement of CCND1 (BCL1/PRAD1) 3′ untranslated region in mantle-cell lymphomas and t(11q13)-associated leukemias. Blood 1994; 83:3689-3696 (Pubitemid 24175560)
20. Mazumder B, Seshadri V, Fox PL. Translational control by the 3'-UTR: the ends specify the means. Trends Biochem Sci 2003; 28:91-98 (Pubitemid 36165138)
21. Pesole G, Liuni S, Grillo G, Saccone C. Structural and compositional features of untranslated regions of eukaryotic mRNAs. Gene 1997; 205:95-102. (Pubitemid 28029602)
22. Conne B, Stutz A, Vassalli JD. The 3′ untranslated region of messenger RNA: A molecular 'hotspot' for pathology? Nat Med 2000; 6:637-641
23. Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, Roussel MF, Sherr CJ. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev 1993; 7:1559-1571 (Pubitemid 23234349)
24. Asano K, Sakamoto H, Sasaki H, Ochiya T, Yoshida T, Ohishi Y, et al. Tumorigenicity and gene amplification potentials of cyclin D1-overexpressing NIH3T3 cells. Biochem Biophys Res Commun 1995; 217:1169-1176 (Pubitemid 26019775)
25. Jiang W, Kahn SM, Zhou P, Zhang YJ, Cacace AM, Infante AS, et al. Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression. Oncogene 1993; 8:3447-3457 (Pubitemid 23342646)
26. Zhao W, Liu M, Kirkwood KL. p38alpha stabilizes interleukin-6 mRNA via multiple AU-rich elements. J Biol Chem 2008; 283:1778-1785
27. Zhang J, Tsaprailis G, Bowden GT. Nucleolin stabilizes Bcl-XL messenger RNA in response to UVA irradiation. Cancer Res 2008; 68:1046-1054 (Pubitemid 351272222)
28. Fialcowitz-White EJ, Brewer BY, Ballin JD, Willis CD, Toth EA, Wilson GM. Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences. J Biol Chem 2007; 282:20948-20959
29. Rinaldi A, Poretti G, Kwee I, Zucca E, Catapano CV, Tibiletti MG, Bertoni F. Concomitant MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma. Leuk Lymphoma 2007; 48:410-412 (Pubitemid 46994894)
30. Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. Frequent deletions and downregulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002; 99:15524-15529 (Pubitemid 35403967)
31. Linsley PS, Schelter J, Burchard J, Kibukawa M, Martin MM, Bartz SR, et al. Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol 2007; 27:2240-2252 (Pubitemid 46418479)
32. Chen RW, Bemis LT, Amato CM, Myint H, Tran H, Birks DK, et al. Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. Blood 2008; 112:822-829
33. Yu Z, Wang C, Wang M, Li Z, Casimiro MC, Liu M, et al. A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol 2008; 182:509-517
34. Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007; 315:1576-1579 (Pubitemid 46449474)
35. O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005; 435:839-843