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It should be noted that Willner and co-workers have elegantly demonstrated that the allosteric nature of the hemin-binding aptamer (when tethered to other nucleic acid sequences or proteins) can lead to bifunctional molecules capable of detecting various agents of import (including DNA, AMP, lysozyme and glucose)
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It should be noted that Willner and co-workers have elegantly demonstrated that the allosteric nature of the hemin-binding aptamer (when tethered to other nucleic acid sequences or proteins) can lead to bifunctional molecules capable of detecting various agents of import (including DNA, AMP, lysozyme and glucose).
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In addition, Kolpashchikov has recently shown that an ODN containing the hemin-binding aptamer can be split into binary components that selfassemble in the presence of a specific DNA sequence and hence can be used as a probe for detecting single nucleotide polymorphism
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In addition, Kolpashchikov has recently shown that an ODN containing the hemin-binding aptamer can be split into binary components that selfassemble in the presence of a specific DNA sequence and hence can be used as a probe for detecting single nucleotide polymorphism
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However, to the best of our knowledge, there has been no exploration of using the hemin-binding aptamer linked to a synthetic fragment for targeted protein-binding and detection
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However, to the best of our knowledge, there has been no exploration of using the hemin-binding aptamer linked to a synthetic fragment for targeted protein-binding and detection.
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