A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase

Acta Crystallographica Section D: Biological Crystallography

Volumn 65, Issue 11, 2009, Pages 1222-1231

  Lyubimov, Artem Y ^a,d   Chen, Lin ^b   Sampson, Nicole S ^b   Vrielink, Alice ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Flavoproteins; GMC oxidoreductases; Hydrophobic tunnel; Site directed mutagenesis

Indexed keywords

CHOLESTEROL OXIDASE;

ARTICLE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HYDROGEN BOND; ISOMERISM; METABOLISM; MUTATION; OXIDATION REDUCTION REACTION; PH; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BIOCATALYSIS; CHOLESTEROL OXIDASE; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; ISOMERISM; MODELS, MOLECULAR; MUTATION; OXIDATION-REDUCTION; PROTEIN STRUCTURE, TERTIARY;

EID: 70449714707     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444909037421     Document Type: Article

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