Inflammatory cytokine mRNA in monocytes is modified by a recombinant (SP-C)-based surfactant and porcine surfactant

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 31, Issue 5, 2009, Pages 317-323

  Wemhöner, Andreas ^a,c   Rüdiger, Mario ^a,c   Gortner, Ludwig ^b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Chemokines; Cytokines; Inflammation; Lipopolysaccharide; Monocytes

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LUSUPULTIDE; MESSENGER RNA; PORACTANT; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL PRODUCT; PHOSPHOLIPID; RECOMBINANT PROTEIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; INCUBATION TIME; MONOCYTE; PROTEIN EXPRESSION; BIOSYNTHESIS; CELL CULTURE; GENETICS; METABOLISM;

BIOLOGICAL PRODUCTS; CELLS, CULTURED; CYTOKINES; HUMANS; INTERLEUKIN-10; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MONOCYTES; PHOSPHOLIPIDS; RECOMBINANT PROTEINS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70449714024     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2009.31.5.1386592     Document Type: Article

References (24)

1. Jobe, A.H., Ikegami, M. Antenatal infection/inflammation and postnatal lung maturation and injury. Respir Res 2001, 2(1): 27-32.
2. Akei, H., Whitsett, J.A., Buroker, M., Ninomiya, T., Tatsumi, H., Weaver, T.E., Ikegami, M. Surface tension influences cell shape and phagocytosis in alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 2006, 291(4): L572-9.
3. Kramer, B.W., Jobe, A.H., Ikegami, M. Monocyte function in preterm, term, and adult sheep. Pediatr Res 2003, 54(1): 52-57
4. Epaud, R., Ikegami, M., Whitsett, J.A., Jobe, A.H., Weaver, T.E., Akinbi, H.T. Surfactant protein B inhibits endotoxin-induced lung inflammation. Am J Respir Cell Mol Biol 2003, 28(3): 373-378
5. Song, M., Phelps, D.S. Comparison of SP-A and LPS effects on the THP-1 monocytic cell line. Am J Physiol Lung Cell Mol Physiol 2000, 279(1): L110-7.
6. Antal, J.M., Divis, L.T., Erzurum, S.C., Wiedemann, H.P., Thomassen, M.J. Surfactant suppresses NF-kappaB activation in human monocytic cells. Am J Respir Cell Mol Biol 1996, 14(4): 374-379
7. Thomassen, M.J., Meeker, D.P., Antal, J.M., Connors, M.J., Wiedemann, H.P. Synthetic surfactant (Exosurf) inhibits endotoxin-stimulated cytokine secretion by human alveolar macrophages. Am J Respir Cell Mol Biol 1992, 7(3): 257-260
8. Thomassen, M.J., Antal, J.M., Connors, M.J., Meeker, D.P., Wiedemann, H.P. Characterization of Exosurf (surfactant)-mediated suppression of stimulated human alveolar macrophage cytokine responses. Am J Respir Cell Mol Biol 1994, 10(4): 399-404.
9. Rudiger, M., Tolle, A., Meier, W., Rustow, B. Naturally derived commercial surfactants differ in composition of surfactant lipids and in surface viscosity. Am J Physiol Lung Cell Mol Physiol 2005, 288(2): L379-83.
10. Ikegami, M., Jobe, A.H. Injury responses to different surfactants in ventilated premature lamb lungs. Pediatr Res 2002, 51(6): 689-695
11. Spragg, R.G., Lewis, J.F., Wurst, W., Hafner, D., Baughman, R.P., Wewers, M.D., Marsh, J.J. Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant. Am J Respir Crit Care Med 2003, 167(11): 1562-1566
12. Markart, P., Ruppert, C., Wygrecka, M. et al. Patients with ARDS show improvement but not normalisation of alveolar surface activity with surfactant treatment: Putative role of neutral lipids. Thorax 2007, 62(7): 588-594
13. Robertson, B., Halliday, H.L. Principles of surfactant replacement. Biochim Biophys Acta 1998, 1408(2-3): 346-361
14. Fink, L., Stahl, U., Ermert, L., Kummer, W., Seeger, W., Bohle, R.M. Rat porphobilinogen deaminase gene: A pseudogene-free internal standard for laser-assisted cell picking. Biotechniques 1999, 26(3): 510-516
15. Fink, L., Seeger, W., Ermert, L. et al. Real-time quantitative RT-PCR after laser-assisted cell picking. Nat Med 1998, 4(11): 1329-1333
16. Speer, C.P. Inflammation and bronchopulmonary dysplasia. Semin Neonatol 2003, 8(1): 29-38.
17. Guthmann, F., Wissel, H., Schachtrup, C., Tolle, A., Rudiger, M., Spener, F., Rustow, B. Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells. Respir Res 2005, 6(1): 10.
18. Wiernik, A., Curstedt, T., Johansson, A., Jarstrand, C., Robertson, B. Morphology and function of blood monocytes after incubation with lung surfactant. Eur J Respir Dis 1987, 71(5): 410-418
19. Baur, F.M., Brenner, B., Goetze-Speer, B., Neu, S., Speer, C.P. Natural porcine surfactant (Curosurf) down-regulates mRNA of tumor necrosis factor-alpha (TNF-alpha) and TNF-alpha type II receptor in lipopolysaccharide-stimulated monocytes. Pediatr Res 1998, 44(1): 32-36
20. Medzhitov, R., Preston-Hurlburt, P., Janeway, C.A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388(6640): 394-397
21. Shkoda, A., Ruiz, P.A., Daniel, H., Kim, S.C., Rogler, G., Sartor, R.B., Haller, D. Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: Impact on chronic inflammation. Gastroenterology 2007, 132(1): 190-207.
22. Williams, L.M., Sarma, U., Willets, K., Smallie, T., Brennan, F., Foxwell, B.M. Expression of constitutively active STAT3 can replicate the cytokinesuppressive activity of interleukin-10 in human primary macrophages. J Biol Chem 2007, 282(10): 6965-6975
23. Mulugeta, S., Beers, M.F. Surfactant protein C: Its unique properties and emerging immunomodulatory role in the lung. Microbes Infect 2006, 8(8): 2317-2323
24. Tonks, A., Parton, J., Tonks, A.J., Morris, R.H., Finall, A., Jones, K.P., Jackson, S.K. Surfactant phospholipid DPPC downregulates monocyte respiratory burst via modulation of PKC. Am J Physiol Lung Cell Mol Physiol 2005, 288(6): L1070-80.