Synthesis and antimicrobial activities of some new triazolothiadiazoles bearing 4-methylthiobenzyl moiety

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 551-557

  Prasad, D Jagadeesh ^a   Ashok, Mithun ^b   Karegoudar, Prakash ^c   Poojary, Boja ^a   Holla, B Shivarama ^d   Kumari, Nalilu Sucheta ^e  

^a MANGALORE UNIVERSITY   (India)

^b AstraZenica Research Foundation India   (India)

^c SeQuent Scientific Limited   (India)

^d Sri Dharmasthala Manjunatheshwara Institute of Technology   (India)

^e NITTE DEEMED TO BE UNIVERSITY   (India)

Author keywords

Antibacterial; Antifungal; Methylthiobenzyl moiety; Triazolothiadiazole

Indexed keywords

2 FUROIC ACID; 4 AMINO 3 (4 METHYLTHIOBENZYL) 4H 1,2,4 TRIAZOLE 5 THIOL; 4 METHYLTHIOBENZYL DERIVATIVE; 4 METHYLTHIOPHENYL ACETIC ACID; AROMATIC CARBOXYLIC ACID; BENZENE DERIVATIVE; THIADIAZOLE DERIVATIVE; THIOCARBOHYDRAZIDE; THIOL DERIVATIVE; TRIAZOLE DERIVATIVE; TRIAZOLOTHIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

ANTI-INFECTIVE AGENTS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES; TRIAZOLES;

EID: 60349115292     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.03.025     Document Type: Article

References (44)

1. Heindel N.D., and Reid I.R. J. Heterocycl. Chem. 17 (1980) 1087
2. Holla B.S., Kalluraya B., Sridhar K.R., Drake E., Thomas L.M., Bhandary K.K., and Levine M.S. Eur. J. Med. Chem. 29 (1994) 301
3. The Merk Index. 12th ed. (1996), Merk and Co. Inc., Whitehouse Station
4. Haber J. Present status and perspectives on antimycotics with systemic effects. Cas. Lek. Cesk. 140 (2001) 596
5. Brucato A., Copoola A., Gianguzza S., and Provenzano P.M. Bull. Soc. Ital. Sper. 54 (1978) 1051
6. D.L. Coffen, R.I. Fryer, U.S. Patent 3,849,434, 1974;
7. Chem. Abstr. 82 (1973) 730044v
8. M. Shiroki, T. Tahara, K. Araki, Jap. Pat. 75100096, 1975.
9. Povelista F.D., and Gural A.G. Antibiotiki (Mosc) 18 (1973) 71
10. Chem. Abstr. 78 (1973) 93044
11. Sidwell R.W., Allen L.B., Hoffman J.H., Witkowsti J.T., and Simon L.N. Proc. Soc. Exp. Biol. Med. 148 (1975) 854
12. M.C. Shepherd, Proceedings of British Crop Protection Conference, Brighton, vol. 1, 1986, p. 19.
13. Lye H. Modern Selective Fungicides (1987), Longman, Harlow
14. P. Efthimiadis, Proceedings of British Crop Conference, Brighton, vol. 3, 1988, p. 887.
15. Hart C. Drugs for Migraine. Modern Drug Discovery (1999), American Chemical Society
16. G.V. Reet, J. Heeres, L. Wals, Ger. Pat. 2,551,560, 1976;
17. Chem. Abstr. 85 (1976) 94368
18. P.A. Worthington, Proceedings of British Crop Protection Conference, Brighton, vol. 3, 1984, p. 955.
19. Bruch H.A., and Smith W.O. J. Med. Chem. 9 (1996) 405
20. Foroumadi A., Mansouri S., Kiani Z., and Rahamani A. Eur. J. Med. Chem. 38 (2003) 851
21. Ram V.J., Mishra L., Pandey N.H., Kushwaha D.S., Pieters L.A.C., and Vlietinck A.J. J. Heterocycl. Chem. 27 (1990) 351
22. Ergenc N., Ilhan E., and Otuk G. Pharmazie 47 (1992) 59
23. Kalyoncuoglu N., Rollas S., Sur-Altiner D., Yegenoglu Y., and Ong A. Pharmazie 47 (1992) 796
24. Rollas S., Kalyoncuoglu N., Sur-Altiner D., and Yegenoglu Y. Pharmazie 48 (1973) 308
25. Mir I., Siddiqui M.T., and Comrie A. Tetrahedron 26 (1970) 5235
26. Rudnicka W., Foks H., Janowiec M., and Zwolska-Kwiek Z. Acta Pol. Pharm. 43 (1986) 523
27. Chem. Abstr., 108 (1988) 131695b.
28. Holla B.S., Veerndra B., Shivananda M.K., and Poojary B. Eur. J. Med. Chem. 38 (2003) 759
29. Duran A., Dagan H.N., and Rollas S. Farmaco 57 (2002) 55
30. Yale H.L., and Piala J.J. J. Med. Chem. 9 (1996) 42
31. Shah M.H., Mhasalkar M.Y., Palki M.V., Deliwala C.V., and Sheth U.K. J. Pharm. Sci. 58 (1969) 1398
32. Mhasalkar M.Y., Shah M.H., Nikam S.T., Ananthanarayana K.G., and Deliwala C.V. J. Med. Chem. 13 (1970) 672
33. W. Stanely, Ger. Offen. 270 (1977) 42691977;
34. Chem. Abstr. 87 (1977) 20194b
35. Kawakanni F., Yamamoto I., and Kosai Y. Chem. Abstr. 88 (1978) 100351
36. Karabasanagouda T., Adhikari A.V., and Shetty N.S. Eur. J. Med. Chem. 42 (2007) 521
37. Ashok M., and Holla B.S. J. Pharmacol. Toxicol. 2 3 (2007) 256
38. Audrieth L.F., Scott E.S., and Kippur P.S. J. Org. Chem. 19 (1954) 733
39. Akasi H., and Oda K. Rep. Inst. Chem. Res., Kyoto Univ. 19 (1949) 93
40. Chem. Abstr. 45 (1951) 751h
41. Cruickshank R., Duguid J.P., Marion B.P., and Swain R.H.A. Medicinal Microbiology. 12th ed. vol. 11 (1975), Churchill Livingstone, London p. 196
42. Collins A.H. Microbiological Methods. second ed. vol. 11 (1976), Butterworth, London
43. Khan Z.K. In vitro and in vivo screening techniques for bioactivity screening and evaluation. Proceedings of the International Workshop, UNIDO-CDRI (1997) p. 210
44. In: Verma R.S. (Ed). Antifungal Agents: Past, Present and Future Prospects (1998), National Academy of Chemistry and Biology, Lucknow, India