Ischemic preconditioning-induced neuroprotection is associated with differential expression of IL-1β and IL-1 receptor antagonist in the ischemic cortex

Journal of Neuroimmunology

Volumn 217, Issue 1-2, 2009, Pages 14-19

  Shin, Jin A ^a   Park, Eun Mi ^a   Choi, Ji Seung ^a   Seo, Sun Mi ^a   Kang, Jihee Lee ^a   Lee, Kyung Eun ^a   Cho, Sunghee ^b,c  

^a Ewha Womans University School of Medicine   (South Korea)

^b BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Bilateral common carotid artery occlusion; IL 1 receptor antagonist; IL 1 ; Ischemic preconditioning; Middle cerebral artery occlusion

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ISCHEMIC PRECONDITIONING; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CAROTID ARTERY DISEASES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; ISCHEMIC PRECONDITIONING; MALE; MICE; MICE, INBRED C57BL; RNA, MESSENGER; TIME FACTORS;

EID: 70449639909     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.06.001     Document Type: Article

References (36)

1. Allan S.M., Tyrrell P.J., and Rothwell N.J. Interleukin-1 and neuronal injury. Nat. Rev. Immunol. 5 (2005) 629-640
2. Arend W.P. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev. 13 (2002) 323-340
3. Barone F.C., White R.F., Spera P.A., Ellison J., Currie R.W., Wang X., and Feuerstein G.Z. Ischemic preconditioning and brain tolerance: temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression. Stroke 29 (1998) 1937-1950
4. Barrier A., Olaya N., Chiappini F., Roser F., Scatton O., Artus C., Franc B., Dudoit S., Flahault A., Debuire B., Azoulay D., and Lemoine A. Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion. FASEB J. 19 (2005) 1617-1626
5. Betz A.L., Yang G.Y., and Davidson B.L. Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J. Cereb. Blood Flow Metab. 15 (1995) 547-551
6. Bowen K.K., Naylor M., and Vemuganti R. Prevention of inflammation is a mechanism of preconditioning-induced neuroprotection against focal cerebral ischemia. Neurochem. Int. 49 (2006) 127-135
7. Cho S., Park E.M., Zhou P., Frys K., Ross M.E., and Iadecola C. Obligatory role of inducible nitric oxide synthase in ischemic preconditioning. J. Cereb. Blood Flow Metab. 25 (2005) 493-501
8. Choi J.S., Kim S.J., Shin J.A., Lee K.E., and Park E.M. Effects of estrogen on temporal expressions of IL-1β and IL-1ra in rat organotypic hippocampal slices exposed to oxygen-glucose deprivation. Neurosci. Lett. 438 (2008) 233-237
9. Dirnagl U., Iadecola C., and Moskowitz M.A. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 22 (1999) 391-397
10. Dirnagl U., and Meisel A. Endogenous neuroprotection: mitochondria as gateways to cerebral preconditioning?. Neuropharmacology 55 (2008) 334-344
11. Dirnagl U., Simon R.P., and Hallenbeck J.M. Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 26 (2003) 248-254
12. Gidday J.M. Cerebral preconditioning and ischaemic tolerance. Nat. Rev. Neurosci. 7 (2006) 437-448
13. Kirino T. Ischemic tolerance. J. Cereb. Blood Flow Metab. 22 (2002) 1283-1296
14. Kitagawa K., Matsumoto M., Tagaya M., Hata R., Ueda H., Niinobe M., Handa N., Fukunaga R., Kimura K., Mikoshiba K., et al. 'Ischemic tolerance' phenomenon found in the brain. Brain Res. 528 (1990) 21-24
15. Legos J.J., Whitmore R.G., Erhardt J.A., Parsons A.A., Tuma R.F., and Barone F.C. Quantitative changes in interleukin proteins following focal stroke in the rat. Neurosci. Lett. 282 (2000) 189-192
16. Lin T.N., He Y.Y., Wu G., Khan M., and Hsu C.Y. Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke 24 (1993) 117-121
17. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
18. Loddick S.A., and Rothwell N.J. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J. Cereb. Blood Flow Metab. 16 (1996) 932-940
19. Loddick S.A., Wong M.L., Bongiorno P.B., Gold P.W., Licinio J., and Rothwell N.J. Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochem. Biophys. Res. Commun. 234 (1997) 211-215
20. Martin D., Chinookoswong N., and Miller G. The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischemia. Exp. Neurol. 130 (1994) 362-367
21. Mulcahy N.J., Ross J., Rothwell N.J., and Loddick S.A. Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat. Br. J. Pharmacol. 140 (2003) 471-476
22. Murry C.E., Jennings R.B., and Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74 (1986) 1124-1136
23. O'Connor K., Johnson J., Hansen M., Wieseler Frank J., Maksimova E., Watkins L., and Maier S. Peripheral and central proinflammatory cytokine response to a severe acute stressor. Brain Res. 991 (2003) 123-132
24. Ohtsuki T., Ruetzler C.A., Tasaki K., and Hallenbeck J.M. Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons. J. Cereb. Blood Flow Metab. 16 (1996) 1137-1142
25. Palin K., Verrier D., Tridon V., Hurst J., Perry V., Dantzer R., and Lestage J. Influence of the course of brain inflammation on the endogenous IL-1β /IL-1Ra balance in the model of brain delayed-type hypersensitivity response to bacillus Calmette-Guérin in Lewis rats. J. Neuroimmunol. 149 (2004) 22-30
26. Park E.M., Cho B.P., Volpe B.T., Cruz M.O., Joh T.H., and Cho S. Ibuprofen protects ischemia-induced neuronal injury via up-regulating interleukin-1 receptor antagonist expression. Neuroscience 132 (2005) 625-631
27. Park E.M., Cho S., Frys K., Racchumi G., Zhou P., Anrather J., and Iadecola C. Interaction between inducible nitric oxide synthase and poly(ADP-ribose) polymerase in focal ischemic brain injury. Stroke 35 (2004) 2896-2901
28. Pasupathy S., and Homer-Vanniasinkam S. Ischaemic preconditioning protects against ischaemia/reperfusion injury: emerging concepts. Eur. J. Vasc. Endovasc. Surg. 29 (2005) 106-115
29. Pera J., Zawadzka M., Kaminska B., and Szczudlik A. Influence of chemical and ischemic preconditioning on cytokine expression after focal brain ischemia. J. Neurosci. Res. 78 (2004) 132-140
30. Pinteaux E., Rothwell N.J., and Boutin H. Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia. Glia 53 (2006) 551-556
31. Relton J.K., and Rothwell N.J. Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res. Bull. 29 (1992) 243-246
32. Swain J.L., Sabina R.L., Hines J.J., Greenfield Jr. J.C., and Holmes E.W. Repetitive episodes of brief ischaemia (12 min) do not produce a cumulative depletion of high energy phosphate compounds. Cardiovasc. Res. 18 (1984) 264-269
33. Valero N., MarinaEspina L., Bonilla E., and Mosquera J. Melatonin decreases nitric oxide production and lipid peroxidation and increases interleukin-1 beta in the brain of mice infected by the Venezuelan equine encephalomyelitis virus. J. Pineal Res. 42 (2007) 107-112
34. Wang X., Barone F.C., Aiyar N.V., and Feuerstein G.Z. Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats. Stroke 28 (1997) 155-161
35. Wang X., Li X., Currie R.W., Willette R.N., Barone F.C., and Feuerstein G.Z. Application of real-time polymerase chain reaction to quantitate induced expression of interleukin-1beta mRNA in ischemic brain tolerance. J. Neurosci. Res. 59 (2000) 238-246
36. Yamasaki Y., Matsuura N., Shozuhara H., Onodera H., Itoyama Y., and Kogure K. Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26 (1995) 676-680