Ethanolic extract of Casearia sylvestris and its clerodane diterpen (caseargrewiin F) protect against DNA damage at low concentrations and cause DNA damage at high concentrations in mice's blood cells

Mutagenesis

Volumn 24, Issue 6, 2009, Pages 501-506

  De Oliveira, Aline M ^a   Dos Santos, André G ^a   Dos Santos, Raquel A ^b   Csipak, Angélica R ^a   Olivato, Camila ^a   Da Silva, Isabel C ^a   De Freitas, Maura B ^a   Bassi, Carmen L ^c   Cavalheiro, Alberto J ^a   Bolzani, Vanderlan S ^a   Silva, Dulce H S ^a   Sakamoto Hojo, Elza T ^b   Takahashi, Catarina S ^b   Soares, Christiane P ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CASEARGREWIIN F; CASEARIA SYLVESTRIS EXTRACT; CLERODANE DERIVATIVE; CYCLOPHOSPHAMIDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CELL; CASEARIA; CASEARIA SYLVESTRIS; CELL PROTECTION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; GENOTOXICITY; MALE; MICRONUCLEUS TEST; MOUSE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; TREATMENT DURATION;

ANIMALS; BODY WEIGHT; CASEARIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMET ASSAY; DITERPENES; DNA DAMAGE; ETHANOL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, INBRED BALB C; MICRONUCLEUS TESTS; MODELS, CHEMICAL; PLANT EXTRACTS; PLANT LEAVES;

CASEARIA SYLVESTRIS; MUS;

EID: 70449632786     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gep034     Document Type: Article

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