메뉴 건너뛰기




Volumn 23, Issue 6, 2009, Pages 1329-1341

Traditional and New Approaches to the Management of Immune Thrombocytopenia: Issues of When and Who to Treat

Author keywords

Autoimmunity; Bleeding; ITP; Platelets; Thrombocytopenia

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DANAZOL; DAPSONE; DEXAMETHASONE; DOXORUBICIN; ELTROMBOPAG; ESTROGEN; IMMUNOGLOBULIN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PLACEBO; PREDNISONE; PROTEIN KINASE SYK INHIBITOR; RHESUS D ANTIBODY; RITUXIMAB; ROMIPLOSTIM; VALPROIC ACID; VINCA ALKALOID; VINCRISTINE;

EID: 70449629813     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2009.09.004     Document Type: Review
Times cited : (7)

References (47)
  • 1
    • 64049085194 scopus 로고    scopus 로고
    • Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura (ITP) of adults and children: Report from an International Working Group
    • Rodeghiero F., Stasi R., Gernsheimer T., et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura (ITP) of adults and children: Report from an International Working Group. Blood 113 11 (2008) 2386-2393
    • (2008) Blood , vol.113 , Issue.11 , pp. 2386-2393
    • Rodeghiero, F.1    Stasi, R.2    Gernsheimer, T.3
  • 2
    • 0041429528 scopus 로고    scopus 로고
    • Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasone
    • Cheng Y., Wong R.S., Soo Y.O., et al. Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasone. N Engl J Med 349 9 (2003) 831-836
    • (2003) N Engl J Med , vol.349 , Issue.9 , pp. 831-836
    • Cheng, Y.1    Wong, R.S.2    Soo, Y.O.3
  • 3
    • 33846925496 scopus 로고    scopus 로고
    • Gruppo Italiano Malattie EMatologiche dell'Adulto (GIMEMA) Thrombocytopenia Working Party. Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience
    • Mazzucconi M.G., Fazi P., Bernasconi S., et al. Gruppo Italiano Malattie EMatologiche dell'Adulto (GIMEMA) Thrombocytopenia Working Party. Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience. Blood 109 4 (2007) 1401-1407
    • (2007) Blood , vol.109 , Issue.4 , pp. 1401-1407
    • Mazzucconi, M.G.1    Fazi, P.2    Bernasconi, S.3
  • 4
    • 2042544763 scopus 로고    scopus 로고
    • The efficacy and safety of B-cell depletion with anti-CD20 monoclonal antibody in adults with chronic immune thrombocytopenia purpura
    • Cooper N., Stasi R., Cunningham-Rundles S., et al. The efficacy and safety of B-cell depletion with anti-CD20 monoclonal antibody in adults with chronic immune thrombocytopenia purpura. Br J Haematol 125 2 (2004) 232-239
    • (2004) Br J Haematol , vol.125 , Issue.2 , pp. 232-239
    • Cooper, N.1    Stasi, R.2    Cunningham-Rundles, S.3
  • 5
    • 0037085763 scopus 로고    scopus 로고
    • Does treatment with intermittent infusions of IV anti-D allow a proportion of adults with recently diagnosed immune thrombocytopenic purpura (ITP) to avoid splenectomy?
    • Cooper N., Woloski B.M.R., Fodero E.M., et al. Does treatment with intermittent infusions of IV anti-D allow a proportion of adults with recently diagnosed immune thrombocytopenic purpura (ITP) to avoid splenectomy?. Blood 99 6 (2002) 1922-1927
    • (2002) Blood , vol.99 , Issue.6 , pp. 1922-1927
    • Cooper, N.1    Woloski, B.M.R.2    Fodero, E.M.3
  • 6
    • 0242361660 scopus 로고    scopus 로고
    • Initial management of immune thrombocytopenic purpura in adults: a randomized controlled trial comparing intermittent anti-D with routine care
    • George J.N., Raskob G.E., Vesely S.K., et al. Initial management of immune thrombocytopenic purpura in adults: a randomized controlled trial comparing intermittent anti-D with routine care. Am J Hematol 74 3 (2003) 161-169
    • (2003) Am J Hematol , vol.74 , Issue.3 , pp. 161-169
    • George, J.N.1    Raskob, G.E.2    Vesely, S.K.3
  • 7
    • 0027320655 scopus 로고
    • Treatment of adult chronic autoimmune thrombocytopenic purpura with repeated high-dose intravenous immunoglobulin
    • Godeau B., Lesage S., Divine M., et al. Treatment of adult chronic autoimmune thrombocytopenic purpura with repeated high-dose intravenous immunoglobulin. Blood 82 5 (1993) 1415-1421
    • (1993) Blood , vol.82 , Issue.5 , pp. 1415-1421
    • Godeau, B.1    Lesage, S.2    Divine, M.3
  • 8
    • 0023766715 scopus 로고
    • Maintenance treatment of adults with chronic refractory immune thrombocytopenic purpura using repeated intravenous infusions of gammaglobulin
    • Bussel J., Pham L.C., Aledort L., et al. Maintenance treatment of adults with chronic refractory immune thrombocytopenic purpura using repeated intravenous infusions of gammaglobulin. Blood 72 1 (1988) 121-127
    • (1988) Blood , vol.72 , Issue.1 , pp. 121-127
    • Bussel, J.1    Pham, L.C.2    Aledort, L.3
  • 9
    • 38149134581 scopus 로고    scopus 로고
    • Management of refractory immune thrombocytopenic purpura
    • Kalpatthi R., and Bussel J.B. Management of refractory immune thrombocytopenic purpura. Curr Opin Pediatr 20 (2008) 8-16
    • (2008) Curr Opin Pediatr , vol.20 , pp. 8-16
    • Kalpatthi, R.1    Bussel, J.B.2
  • 10
    • 38349128556 scopus 로고    scopus 로고
    • Self-reported health-related quality of life in adults with chronic immune thrombocytopenic purpura
    • McMillan R., Bussel J.B., George J.N., et al. Self-reported health-related quality of life in adults with chronic immune thrombocytopenic purpura. Am J Hematol 83 2 (2008) 150-154
    • (2008) Am J Hematol , vol.83 , Issue.2 , pp. 150-154
    • McMillan, R.1    Bussel, J.B.2    George, J.N.3
  • 11
    • 33847633582 scopus 로고    scopus 로고
    • A disease-specific measure of health-related quality of life for use in adults with immune thrombocytopenic purpura: its development and validation
    • Mathias S.D., Bussel J.B., George J.N., et al. A disease-specific measure of health-related quality of life for use in adults with immune thrombocytopenic purpura: its development and validation. Health Qual Life Outcomes 5 (2007) 11
    • (2007) Health Qual Life Outcomes , vol.5 , pp. 11
    • Mathias, S.D.1    Bussel, J.B.2    George, J.N.3
  • 12
    • 58449105994 scopus 로고    scopus 로고
    • Improved quality of life for romiplostim-treated patients with chronic immune thrombocytopenic purpura: results from two randomized, placebo-controlled trials
    • George J.N., Mathias S.D., Go R.S., et al. Improved quality of life for romiplostim-treated patients with chronic immune thrombocytopenic purpura: results from two randomized, placebo-controlled trials. Br J Haematol 144 3 (2009) 409-415
    • (2009) Br J Haematol , vol.144 , Issue.3 , pp. 409-415
    • George, J.N.1    Mathias, S.D.2    Go, R.S.3
  • 13
    • 60249095603 scopus 로고    scopus 로고
    • Oral eltrombopag for the long-term treatment of patients with chronic idiopathic thrombocytopenic purpura: results of a phase III, double- blind, placebo-controlled study (RAISE)
    • [ASH Annual Meeting Abstracts]
    • Cheng G., Saleh M.N., Bussel J.B., et al. Oral eltrombopag for the long-term treatment of patients with chronic idiopathic thrombocytopenic purpura: results of a phase III, double- blind, placebo-controlled study (RAISE). [ASH Annual Meeting Abstracts]. Blood 112 (2008) 400
    • (2008) Blood , vol.112 , pp. 400
    • Cheng, G.1    Saleh, M.N.2    Bussel, J.B.3
  • 14
    • 77949434753 scopus 로고    scopus 로고
    • Drug-induced thrombocytopenia: Pathogenesis, evaluation, and management. ASH Education
    • in press
    • George JN, Aster RH. Drug-induced thrombocytopenia: pathogenesis, evaluation, and management. ASH Education. Hematology 2009, in press.
    • (2009) Hematology
    • George, J.N.1    Aster, R.H.2
  • 15
    • 0034457590 scopus 로고    scopus 로고
    • Valproate: hematologic toxicities of sodium valproate
    • Acharya S., and Bussel J.B. Valproate: hematologic toxicities of sodium valproate. J Pediatr Hematol Oncol 22 1 (2000) 62-65
    • (2000) J Pediatr Hematol Oncol , vol.22 , Issue.1 , pp. 62-65
    • Acharya, S.1    Bussel, J.B.2
  • 16
    • 4544370451 scopus 로고    scopus 로고
    • Adverse effects of estrogen therapy in a subset of women with ITP
    • Onel K., and Bussel J.B. Adverse effects of estrogen therapy in a subset of women with ITP. J Thromb Haemost 2 4 (2004) 670-671
    • (2004) J Thromb Haemost , vol.2 , Issue.4 , pp. 670-671
    • Onel, K.1    Bussel, J.B.2
  • 17
    • 0023872381 scopus 로고
    • The effect of azidothymidine on HIV-related thrombocytopenia
    • Hymes K.B., Greene J.B., and Karpatkin S. The effect of azidothymidine on HIV-related thrombocytopenia. N Engl J Med 318 8 (1988) 516-517
    • (1988) N Engl J Med , vol.318 , Issue.8 , pp. 516-517
    • Hymes, K.B.1    Greene, J.B.2    Karpatkin, S.3
  • 18
    • 70449634674 scopus 로고    scopus 로고
    • Brief report: Risk factors for thrombocytopenia in HIV-infected persons in the era of potent antiretroviral therapy
    • in press
    • Marks KM, Clarke RMA, Bussel JB, Talal AH, Glesby MJ. Brief report: risk factors for thrombocytopenia in HIV-infected persons in the era of potent antiretroviral therapy. JAIDS 2009, in press.
    • (2009) JAIDS
    • Marks, K.M.1    Clarke, R.M.A.2    Bussel, J.B.3    Talal, A.H.4    Glesby, M.J.5
  • 19
    • 21344457892 scopus 로고    scopus 로고
    • Hepatitis C virus-related thrombocytopenia: clinical and laboratory characteristics compared with chronic immune thrombocytopenic purpura
    • Rajan S.K., Espina B.M., and Liebman H.A. Hepatitis C virus-related thrombocytopenia: clinical and laboratory characteristics compared with chronic immune thrombocytopenic purpura. Br J Haematol 129 6 (2005) 818-824
    • (2005) Br J Haematol , vol.129 , Issue.6 , pp. 818-824
    • Rajan, S.K.1    Espina, B.M.2    Liebman, H.A.3
  • 20
    • 60849086771 scopus 로고    scopus 로고
    • Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura. A systematic review
    • Stasi R., Sarpatwari A., Segal J.B., et al. Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura. A systematic review. Blood 113 6 (2009) 1231-1240
    • (2009) Blood , vol.113 , Issue.6 , pp. 1231-1240
    • Stasi, R.1    Sarpatwari, A.2    Segal, J.B.3
  • 21
    • 66949169194 scopus 로고    scopus 로고
    • Cytomegalovirus causes refractory immune thrombocytopenic purpura
    • DiMaggio D., Anderson A., and Bussel J.B. Cytomegalovirus causes refractory immune thrombocytopenic purpura. Br J Haematol 146 1 (2009) 104-112
    • (2009) Br J Haematol , vol.146 , Issue.1 , pp. 104-112
    • DiMaggio, D.1    Anderson, A.2    Bussel, J.B.3
  • 22
    • 0033051584 scopus 로고    scopus 로고
    • Is it necessary to test patients with immune thrombocytopenic purpura (ITP) for seropositivity to HTLV-1?
    • Calleja E., Klein R., and Bussel J. Is it necessary to test patients with immune thrombocytopenic purpura (ITP) for seropositivity to HTLV-1?. Am J Hematol 61 (1999) 94-97
    • (1999) Am J Hematol , vol.61 , pp. 94-97
    • Calleja, E.1    Klein, R.2    Bussel, J.3
  • 23
    • 20144380943 scopus 로고    scopus 로고
    • Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS)
    • Teachey D.T., Manno C.S., Axsom K.M., et al. Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS). Blood 105 6 (2005) 2443-2448
    • (2005) Blood , vol.105 , Issue.6 , pp. 2443-2448
    • Teachey, D.T.1    Manno, C.S.2    Axsom, K.M.3
  • 24
    • 67650496601 scopus 로고    scopus 로고
    • Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS)
    • Rao V.K., Price S., Perkins K., et al. Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatr Blood Cancer 52 7 (2009) 847-852
    • (2009) Pediatr Blood Cancer , vol.52 , Issue.7 , pp. 847-852
    • Rao, V.K.1    Price, S.2    Perkins, K.3
  • 25
    • 44449097509 scopus 로고    scopus 로고
    • Autoimmune manifestations in common variable immunodeficiency
    • Cunningham-Rundles C. Autoimmune manifestations in common variable immunodeficiency. J Clin Immunol 28 Suppl 1 (2008) S42-S45
    • (2008) J Clin Immunol , vol.28 , Issue.SUPPL. 1
    • Cunningham-Rundles, C.1
  • 26
    • 35748953111 scopus 로고    scopus 로고
    • Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: clinical and immunologic outcomes in heterozygotes
    • Zhang L., Radigan L., Salzer U., et al. Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: clinical and immunologic outcomes in heterozygotes. J Allergy Clin Immunol 120 (2007) 1178-1185
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 1178-1185
    • Zhang, L.1    Radigan, L.2    Salzer, U.3
  • 27
    • 27144509749 scopus 로고    scopus 로고
    • How I treat idiopathic thrombocytopenic purpura (ITP)
    • Cines D., and Bussel J. How I treat idiopathic thrombocytopenic purpura (ITP). Blood 106 (2005) 2244-2251
    • (2005) Blood , vol.106 , pp. 2244-2251
    • Cines, D.1    Bussel, J.2
  • 28
    • 0034641010 scopus 로고    scopus 로고
    • The bleeding risk and natural history of idiopathic thrombocytopenic purpura in patients with persistent low platelet counts
    • Cohen Y.C., Djulbegovic B., Shamai-Lubovitz O., et al. The bleeding risk and natural history of idiopathic thrombocytopenic purpura in patients with persistent low platelet counts. Arch Intern Med 160 11 (2000) 1630-1638
    • (2000) Arch Intern Med , vol.160 , Issue.11 , pp. 1630-1638
    • Cohen, Y.C.1    Djulbegovic, B.2    Shamai-Lubovitz, O.3
  • 29
    • 0035353206 scopus 로고    scopus 로고
    • Morbidity and mortality in adults with idiopathic thrombocytopenic purpura
    • Portielje J.E., Westendorp R.G., Kluin-Nelemans H.C., et al. Morbidity and mortality in adults with idiopathic thrombocytopenic purpura. Blood 97 9 (2001) 2549-2554
    • (2001) Blood , vol.97 , Issue.9 , pp. 2549-2554
    • Portielje, J.E.1    Westendorp, R.G.2    Kluin-Nelemans, H.C.3
  • 30
    • 51249106397 scopus 로고    scopus 로고
    • Refractory immune thrombocytopenic purpura: current strategies for investigation and management
    • Psaila B., and Bussel J.B. Refractory immune thrombocytopenic purpura: current strategies for investigation and management. Br J Haematol 143 1 (2008) 16-26
    • (2008) Br J Haematol , vol.143 , Issue.1 , pp. 16-26
    • Psaila, B.1    Bussel, J.B.2
  • 31
    • 7244232710 scopus 로고    scopus 로고
    • Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response, and surgical complications
    • Kojouri K., Vesely S.K., Terrell D.R., et al. Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response, and surgical complications. Blood 104 9 (2004) 2623-2634
    • (2004) Blood , vol.104 , Issue.9 , pp. 2623-2634
    • Kojouri, K.1    Vesely, S.K.2    Terrell, D.R.3
  • 32
    • 0037107253 scopus 로고    scopus 로고
    • Vascular dementia in patients with immune thrombocytopenic purpura
    • Ahn Y.S., Horstman L.L., Jy W., et al. Vascular dementia in patients with immune thrombocytopenic purpura. Thromb Res 107 6 (2002) 337-344
    • (2002) Thromb Res , vol.107 , Issue.6 , pp. 337-344
    • Ahn, Y.S.1    Horstman, L.L.2    Jy, W.3
  • 34
    • 66549130454 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project
    • Carson K.R., Evens A.M., Richey E.A., et al. Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project. Blood 113 20 (2009) 4834-4840
    • (2009) Blood , vol.113 , Issue.20 , pp. 4834-4840
    • Carson, K.R.1    Evens, A.M.2    Richey, E.A.3
  • 35
    • 13444291163 scopus 로고    scopus 로고
    • Chronic immune thrombocytopenia purpura (ITP) in children: assessment of rituximab treatment
    • Wang J., Wiley J., Luddy R., et al. Chronic immune thrombocytopenia purpura (ITP) in children: assessment of rituximab treatment. J Pediatr 146 2 (2005) 217-221
    • (2005) J Pediatr , vol.146 , Issue.2 , pp. 217-221
    • Wang, J.1    Wiley, J.2    Luddy, R.3
  • 36
    • 33750035507 scopus 로고    scopus 로고
    • Effect of a novel thrombopoiesis-stimulating protein (AMG 531) in chronic immune thrombocytopenic purpura
    • Bussel J.B., Kuter D.J., George J.N., et al. Effect of a novel thrombopoiesis-stimulating protein (AMG 531) in chronic immune thrombocytopenic purpura. N Engl J Med 355 (2006) 1672-1681
    • (2006) N Engl J Med , vol.355 , pp. 1672-1681
    • Bussel, J.B.1    Kuter, D.J.2    George, J.N.3
  • 37
    • 38649120593 scopus 로고    scopus 로고
    • Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomized controlled trial
    • Kuter D.J., Bussel J.B., Lyons R.M., et al. Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomized controlled trial. Lancet 371 (2008) 395-403
    • (2008) Lancet , vol.371 , pp. 395-403
    • Kuter, D.J.1    Bussel, J.B.2    Lyons, R.M.3
  • 38
    • 63849111465 scopus 로고    scopus 로고
    • Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP
    • Bussel J.B., Kuter D., Pullarkat V.A., et al. Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP. Blood 113 10 (2009) 2161-2171
    • (2009) Blood , vol.113 , Issue.10 , pp. 2161-2171
    • Bussel, J.B.1    Kuter, D.2    Pullarkat, V.A.3
  • 39
    • 36549001698 scopus 로고    scopus 로고
    • Eltrombopag, an oral platelet growth factor, for the treatment of patients with chronic idiopathic thrombocytopenic purpura
    • Bussel J.B., Cheng G., Saleh M.N., et al. Eltrombopag, an oral platelet growth factor, for the treatment of patients with chronic idiopathic thrombocytopenic purpura. N Engl J Med 357 22 (2007) 2237-2247
    • (2007) N Engl J Med , vol.357 , Issue.22 , pp. 2237-2247
    • Bussel, J.B.1    Cheng, G.2    Saleh, M.N.3
  • 40
    • 36549047972 scopus 로고    scopus 로고
    • TPL102357 Study Group. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
    • McHutchison J.G., Dusheiko G., Shiffman M.L., et al. TPL102357 Study Group. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med 357 22 (2007) 2227-2236
    • (2007) N Engl J Med , vol.357 , Issue.22 , pp. 2227-2236
    • McHutchison, J.G.1    Dusheiko, G.2    Shiffman, M.L.3
  • 41
    • 60249099882 scopus 로고    scopus 로고
    • During treatment of chronic idiopathic thrombocytopenic purpura (ITP): a randomized, double blind, placebo-controlled study
    • Bussel J.B., Provan D., Shamsi T., et al. During treatment of chronic idiopathic thrombocytopenic purpura (ITP): a randomized, double blind, placebo-controlled study. Lancet 373 9664 (2009) 641-648
    • (2009) Lancet , vol.373 , Issue.9664 , pp. 641-648
    • Bussel, J.B.1    Provan, D.2    Shamsi, T.3
  • 42
    • 0024418966 scopus 로고
    • Therapy of chronic idiopathic thrombocytopenic purpura in adults
    • Berchtold P., and McMillan R. Therapy of chronic idiopathic thrombocytopenic purpura in adults. Blood 74 7 (1989) 2309-2317
    • (1989) Blood , vol.74 , Issue.7 , pp. 2309-2317
    • Berchtold, P.1    McMillan, R.2
  • 43
    • 0037220338 scopus 로고    scopus 로고
    • High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia
    • Huhn R.D., Fogarty P.F., Nakamura R., et al. High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia. Blood 101 1 (2003) 71-77
    • (2003) Blood , vol.101 , Issue.1 , pp. 71-77
    • Huhn, R.D.1    Fogarty, P.F.2    Nakamura, R.3
  • 44
    • 0027406140 scopus 로고
    • Combination chemotherapy in refractory immune thrombocytopenic purpura
    • Figueroa M., Gehlsen J., Hammond D., et al. Combination chemotherapy in refractory immune thrombocytopenic purpura. N Engl J Med 328 17 (1993) 1226-1229
    • (1993) N Engl J Med , vol.328 , Issue.17 , pp. 1226-1229
    • Figueroa, M.1    Gehlsen, J.2    Hammond, D.3
  • 45
    • 0035799791 scopus 로고    scopus 로고
    • Long-term outcomes after treatment for refractory immune thrombocytopenic purpura
    • McMillan R. Long-term outcomes after treatment for refractory immune thrombocytopenic purpura. N Engl J Med 344 18 (2001) 1402-1403
    • (2001) N Engl J Med , vol.344 , Issue.18 , pp. 1402-1403
    • McMillan, R.1
  • 46
    • 36348946412 scopus 로고    scopus 로고
    • Multi-agent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP)
    • Boruchov D.M., Gururangan S., Driscoll M.C., et al. Multi-agent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP). Blood 110 10 (2007) 3526-3531
    • (2007) Blood , vol.110 , Issue.10 , pp. 3526-3531
    • Boruchov, D.M.1    Gururangan, S.2    Driscoll, M.C.3
  • 47
    • 65349104905 scopus 로고    scopus 로고
    • Of mice and men: an open label pilot study for treatment of immune thrombocytopenic purpura (ITP) by an inhibitor of syk
    • Podolanczuk A., Lazarus A.H., Crow A.R., et al. Of mice and men: an open label pilot study for treatment of immune thrombocytopenic purpura (ITP) by an inhibitor of syk. Blood 113 14 (2009) 3154-3160
    • (2009) Blood , vol.113 , Issue.14 , pp. 3154-3160
    • Podolanczuk, A.1    Lazarus, A.H.2    Crow, A.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.