Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: Clinical and immunologic outcomes in heterozygotes

Journal of Allergy and Clinical Immunology

Volumn 120, Issue 5, 2007, Pages 1178-1185

  Zhang, Li ^a   Radigan, Lin ^a   Salzer, Ulrich ^b   Behrens, Timothy W ^c   Grimbacher, Bodo ^b,d   Diaz, George ^a   Bussel, James ^e   Cunningham Rundles, Charlotte ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b TU BERGAKADEMIE FREIBERG   (Germany)

^c GENENTECH INC   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

B cell; Common variable immune deficiency; IgA; IgG; immune thrombocytopenia purpura; splenectomy; TACI

Indexed keywords

APRIL PROTEIN; CALCIUM; CYCLOPHILIN; GENOMIC DNA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LIGAND;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE THROMBOCYTOPENIA; AUTOIMMUNITY; B LYMPHOCYTE; CELL PROLIFERATION; CLINICAL ARTICLE; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; CULTURE TECHNIQUE; DNA SEQUENCE; DOMINANT INHERITANCE; ENVIRONMENTAL FACTOR; FEMALE; GENE MUTATION; HEREDITY; HETEROZYGOTE; HUMAN; IMMUNOGLOBULIN PRODUCTION; LIGAND BINDING; LYMPHOID HYPERPLASIA; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN BINDING; SPLENECTOMY; SPLENOMEGALY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AUTOIMMUNITY; B-LYMPHOCYTES; COMMON VARIABLE IMMUNODEFICIENCY; DNA MUTATIONAL ANALYSIS; FEMALE; HETEROZYGOTE; HUMANS; HYPERPLASIA; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MUTATION; PEDIGREE; PROGNOSIS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13;

EID: 35748953111     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.10.001     Document Type: Article

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