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Volumn 20, Issue 5, 2009, Pages 511-515

Overcoming self-destruction in the pancreas

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE DISEASE; BETA CELL; DRUG DISCOVERY; EMBRYONIC STEM CELLS; GLUCOSE HOMEOSTASIS; IMMUNE SUPPRESSION; ISLET TRANSPLANTATION; MOUSE MODELS; PANCREATIC BETA CELLS; PANCREATIC TISSUE; STEM CELL; TYPE 1 DIABETES;

EID: 70449623531     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.copbio.2009.09.009     Document Type: Review
Times cited : (6)

References (44)
  • 1
    • 0026646694 scopus 로고
    • The murine autoimmune diabetes model: NOD and related strains
    • Kikutani H., and Makino S. The murine autoimmune diabetes model: NOD and related strains. Adv Immunol 51 (1992) 285-322
    • (1992) Adv Immunol , vol.51 , pp. 285-322
    • Kikutani, H.1    Makino, S.2
  • 2
    • 0025647147 scopus 로고
    • Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages
    • Hutchings P., Rosen H., O'Reilly L., Simpson E., Gordon S., and Cooke A. Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages. Nature 348 (1990) 639-642
    • (1990) Nature , vol.348 , pp. 639-642
    • Hutchings, P.1    Rosen, H.2    O'Reilly, L.3    Simpson, E.4    Gordon, S.5    Cooke, A.6
  • 3
    • 0023905731 scopus 로고
    • Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice
    • Miller B.J., Appel M.C., O'Neil J.J., and Wicker L.S. Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice. J Immunol 140 (1988) 52-58
    • (1988) J Immunol , vol.140 , pp. 52-58
    • Miller, B.J.1    Appel, M.C.2    O'Neil, J.J.3    Wicker, L.S.4
  • 4
    • 0028294143 scopus 로고
    • Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice
    • Nagata M., Santamaria P., Kawamura T., Utsugi T., and Yoon J.W. Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice. J Immunol 152 (1994) 2042-2050
    • (1994) J Immunol , vol.152 , pp. 2042-2050
    • Nagata, M.1    Santamaria, P.2    Kawamura, T.3    Utsugi, T.4    Yoon, J.W.5
  • 6
    • 0028922437 scopus 로고
    • Genetic control of autoimmune diabetes in the NOD mouse
    • Wicker L.S., Todd J.A., and Peterson L.B. Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol 13 (1995) 179-200
    • (1995) Annu Rev Immunol , vol.13 , pp. 179-200
    • Wicker, L.S.1    Todd, J.A.2    Peterson, L.B.3
  • 8
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y., Brown J., Martinez O.I., and Melton D.A. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429 (2004) 41-46
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 12
    • 27744603796 scopus 로고    scopus 로고
    • Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?
    • Meier J.J., Bhushan A., Butler A.E., Rizza R.A., and Butler P.C. Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?. Diabetologia 48 (2005) 2221-2228
    • (2005) Diabetologia , vol.48 , pp. 2221-2228
    • Meier, J.J.1    Bhushan, A.2    Butler, A.E.3    Rizza, R.A.4    Butler, P.C.5
  • 13
    • 0029557377 scopus 로고
    • IPF1, a homeodomain protein with a dual function in pancreas development
    • Jonsson J., Ahlgren U., Edlund T., and Edlund H. IPF1, a homeodomain protein with a dual function in pancreas development. Int J Dev Biol 39 (1995) 789-798
    • (1995) Int J Dev Biol , vol.39 , pp. 789-798
    • Jonsson, J.1    Ahlgren, U.2    Edlund, T.3    Edlund, H.4
  • 14
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J., Carlsson L., Edlund T., and Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371 (1994) 606-609
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 15
    • 0027958044 scopus 로고
    • Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
    • Chatenoud L., Thervet E., Primo J., and Bach J.F. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci U S A 91 (1994) 123-127
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 123-127
    • Chatenoud, L.1    Thervet, E.2    Primo, J.3    Bach, J.F.4
  • 16
    • 0026680392 scopus 로고
    • The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice
    • Hutchings P., O'Reilly L., Parish N.M., Waldmann H., and Cooke A. The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice. Eur J Immunol 22 (1992) 1913-1918
    • (1992) Eur J Immunol , vol.22 , pp. 1913-1918
    • Hutchings, P.1    O'Reilly, L.2    Parish, N.M.3    Waldmann, H.4    Cooke, A.5
  • 17
    • 20044375937 scopus 로고    scopus 로고
    • A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • Herold K.C., Gitelman S.E., Masharani U., Hagopian W., Bisikirska B., Donaldson D., Rother K., Diamond B., Harlan D.M., and Bluestone J.A. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54 (2005) 1763-1769
    • (2005) Diabetes , vol.54 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3    Hagopian, W.4    Bisikirska, B.5    Donaldson, D.6    Rother, K.7    Diamond, B.8    Harlan, D.M.9    Bluestone, J.A.10
  • 19
    • 33847364499 scopus 로고    scopus 로고
    • Patients with chronic pancreatitis have islet progenitor cells in their ducts, but reversal of overt diabetes in NOD mice by anti-CD3 shows no evidence for islet regeneration
    • Phillips J.M., O'Reilly L., Bland C., Foulis A.K., and Cooke A. Patients with chronic pancreatitis have islet progenitor cells in their ducts, but reversal of overt diabetes in NOD mice by anti-CD3 shows no evidence for islet regeneration. Diabetes 56 (2007) 634-640
    • (2007) Diabetes , vol.56 , pp. 634-640
    • Phillips, J.M.1    O'Reilly, L.2    Bland, C.3    Foulis, A.K.4    Cooke, A.5
  • 20
    • 34848887156 scopus 로고    scopus 로고
    • Recovery from diabetes in mice by beta cell regeneration
    • Nir T., Melton D.A., and Dor Y. Recovery from diabetes in mice by beta cell regeneration. J Clin Invest 117 (2007) 2553-2561
    • (2007) J Clin Invest , vol.117 , pp. 2553-2561
    • Nir, T.1    Melton, D.A.2    Dor, Y.3
  • 21
    • 0034663778 scopus 로고    scopus 로고
    • Nondepleting anti-CD4 has an immediate action on diabetogenic effector cells, halting their destruction of pancreatic beta cells
    • Phillips J.M., Harach S.Z., Parish N.M., Fehervari Z., Haskins K., and Cooke A. Nondepleting anti-CD4 has an immediate action on diabetogenic effector cells, halting their destruction of pancreatic beta cells. J Immunol 165 (2000) 1949-1955
    • (2000) J Immunol , vol.165 , pp. 1949-1955
    • Phillips, J.M.1    Harach, S.Z.2    Parish, N.M.3    Fehervari, Z.4    Haskins, K.5    Cooke, A.6
  • 22
    • 0141796312 scopus 로고    scopus 로고
    • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • Belghith M., Bluestone J.A., Barriot S., Megret J., Bach J.F., and Chatenoud L. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9 (2003) 1202-1208
    • (2003) Nat Med , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3    Megret, J.4    Bach, J.F.5    Chatenoud, L.6
  • 23
    • 34247638529 scopus 로고    scopus 로고
    • TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas
    • Tulachan S.S., Tei E., Hembree M., Crisera C., Prasadan K., Koizumi M., Shah S., Guo P., Bottinger E., and Gittes G.K. TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol 305 (2007) 508-521
    • (2007) Dev Biol , vol.305 , pp. 508-521
    • Tulachan, S.S.1    Tei, E.2    Hembree, M.3    Crisera, C.4    Prasadan, K.5    Koizumi, M.6    Shah, S.7    Guo, P.8    Bottinger, E.9    Gittes, G.K.10
  • 25
    • 24144446405 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice
    • Suarez-Pinzon W.L., Yan Y., Power R., Brand S.J., and Rabinovitch A. Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice. Diabetes 54 (2005) 2596-2601
    • (2005) Diabetes , vol.54 , pp. 2596-2601
    • Suarez-Pinzon, W.L.1    Yan, Y.2    Power, R.3    Brand, S.J.4    Rabinovitch, A.5
  • 27
    • 0037464545 scopus 로고    scopus 로고
    • Transplanted bone marrow regenerates liver by cell fusion
    • Vassilopoulos G., Wang P.R., and Russell D.W. Transplanted bone marrow regenerates liver by cell fusion. Nature 422 (2003) 901-904
    • (2003) Nature , vol.422 , pp. 901-904
    • Vassilopoulos, G.1    Wang, P.R.2    Russell, D.W.3
  • 29
    • 0034637810 scopus 로고    scopus 로고
    • Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation
    • Chopp M., Zhang X.H., Li Y., Wang L., Chen J., Lu D., Lu M., and Rosenblum M. Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. Neuroreport 11 (2000) 3001-3005
    • (2000) Neuroreport , vol.11 , pp. 3001-3005
    • Chopp, M.1    Zhang, X.H.2    Li, Y.3    Wang, L.4    Chen, J.5    Lu, D.6    Lu, M.7    Rosenblum, M.8
  • 31
    • 0037364517 scopus 로고    scopus 로고
    • In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion
    • Ianus A., Holz G.G., Theise N.D., and Hussain M.A. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest 111 (2003) 843-850
    • (2003) J Clin Invest , vol.111 , pp. 843-850
    • Ianus, A.1    Holz, G.G.2    Theise, N.D.3    Hussain, M.A.4
  • 32
    • 1442326000 scopus 로고    scopus 로고
    • No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo
    • Lechner A., Yang Y.G., Blacken R.A., Wang L., Nolan A.L., and Habener J.F. No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo. Diabetes 53 (2004) 616-623
    • (2004) Diabetes , vol.53 , pp. 616-623
    • Lechner, A.1    Yang, Y.G.2    Blacken, R.A.3    Wang, L.4    Nolan, A.L.5    Habener, J.F.6
  • 33
    • 0346099384 scopus 로고    scopus 로고
    • Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury
    • Mathews V., Hanson P.T., Ford E., Fujita J., Polonsky K.S., and Graubert T.A. Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury. Diabetes 53 (2004) 91-98
    • (2004) Diabetes , vol.53 , pp. 91-98
    • Mathews, V.1    Hanson, P.T.2    Ford, E.3    Fujita, J.4    Polonsky, K.S.5    Graubert, T.A.6
  • 34
    • 33847775017 scopus 로고    scopus 로고
    • Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice
    • Zhang C., Todorov I., Lin C.L., Atkinson M., Kandeel F., Forman S., and Zeng D. Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice. Proc Natl Acad Sci U S A 104 (2007) 2337-2342
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 2337-2342
    • Zhang, C.1    Todorov, I.2    Lin, C.L.3    Atkinson, M.4    Kandeel, F.5    Forman, S.6    Zeng, D.7
  • 35
    • 19544386310 scopus 로고    scopus 로고
    • Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells
    • Fujikawa T., Oh S.H., Pi L., Hatch H.M., Shupe T., and Petersen B.E. Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells. Am J Pathol 166 (2005) 1781-1791
    • (2005) Am J Pathol , vol.166 , pp. 1781-1791
    • Fujikawa, T.1    Oh, S.H.2    Pi, L.3    Hatch, H.M.4    Shupe, T.5    Petersen, B.E.6
  • 36
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky N., Blondel O., Laeng P., Velasco I., Ravin R., and McKay. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292 (2001) 1389-1394
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay6
  • 41
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K., Ichisaka T., and Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 448 (2007) 313-317
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 42
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., and Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006) 663-676
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 44
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • Huangfu D., Maehr R., Guo W., Eijkelenboom A., Snitow M., Chen A.E., and Melton D.A. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 26 (2008) 795-797
    • (2008) Nat Biotechnol , vol.26 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3    Eijkelenboom, A.4    Snitow, M.5    Chen, A.E.6    Melton, D.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.