A hydrodynamic analysis of APOBEC3G reveals a monomer-dimer-tetramer self-association that has implications for anti-HIV function

Biochemistry

Volumn 48, Issue 45, 2009, Pages 10685-10687

  Salter, Jason D ^a   Krucinska, Jolanta ^a   Raina, Jay ^b   Smith, Harold C ^a   Wedekind, Joseph E ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b ImmunoDiagnostics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-HIV; CELL TYPES; CYLINDRICAL SHAPES; HYDRODYNAMIC ANALYSIS; HYDRODYNAMIC MODELING; OLIGOMERIC STATE; QUATERNARY STRUCTURE; RNA BINDING; SEDIMENTATION VELOCITIES; SELF-ASSOCIATIONS; TETRAMERS;

ASSOCIATION REACTIONS; FLUID DYNAMICS; HYDRODYNAMICS; MOLECULAR MASS; RNA; VIRUSES;

NUCLEIC ACIDS;

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; DIMER; MONOMER; TETRAMER;

ANTIVIRAL ACTIVITY; ARTICLE; EQUILIBRIUM CONSTANT; HUMAN IMMUNODEFICIENCY VIRUS; HYDRODYNAMICS; MOLECULAR WEIGHT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; SEDIMENTATION RATE; VELOCITY;

ANTI-HIV AGENTS; BIOPOLYMERS; CYTIDINE DEAMINASE; MODELS, MOLECULAR; MOLECULAR WEIGHT;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 70449560591     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901642c     Document Type: Article

References (25)

1. Sheehy, A. M., Gaddis, N. C., Choi, J. D., and Malim, M. H. (2002) Nature 418, 646-650.
2. Chiu, Y. L., and Greene, W. C. (2008) Annu. Rev. Immunol. 26, 317-353.
3. Harris, R. S., Bishop, K. N., Sheehy, A. M., Craig, H. M., Petersen-Mahrt, S. K., Watt, I. N., Neuberger, M. S., and Malim, M. H. (2003) Cell 113, 803-809.
4. Mangeat, B., Turelli, P., Caron, G., Friedli, M., Perrin, L., and Trono, D. (2003) Nature 424, 99-103.
5. Yu, X., Yu, Y., Liu, B., Luo, K., Kong, W., Mao, P., and Yu, X. F. (2003) Science 302, 1056-1060.
6. Conticello, S. G., Harris, R. S., and Neuberger, M. S. (2003) Curr. Biol. 13, 2009-2013.
7. Marin, M., Rose, K. M., Kozak, S. L., and Kabat, D. (2003) Nat. Med. 9, 1398-1403.
8. Luo, K., Liu, B., Xiao, Z., Yu, Y., Yu, X., Gorelick, R., and Yu, X. F. (2004) J. Virol. 78, 11841-11852.
9. Zennou, V., Perez-Caballero, D., Gottlinger, H., and Bieniasz, P. D. (2004) J. Virol. 78, 12058-12061.
10. Chiu, Y. L., Soros, V. B., Kreisberg, J. F., Stopak, K., Yonemoto, W., and Greene, W. C. (2005) Nature 435, 108-114.
11. Chen, K. M., Martemyanova, N., Lu, Y., Shindo, K., Matsuo, H., and Harris, R. S. (2007) FEBS Lett. 581, 4761-4766.
12. Friew, Y. N., Boyko, V., Hu, W. S., and Pathak, V. K. (2009) Retrovirology 6, 56.
13. Wedekind, J. E., Gillilan, R., Janda, A., Krucinska, J., Salter, J. D., Bennett, R. P., Raina, J., and Smith, H. C. (2006) J. Biol. Chem. 281, 38122-38126.
14. Bennett, R. P., Salter, J. D., Liu, X., Wedekind, J. E., and Smith, H. C. (2008) J. Biol. Chem. 283, 33329-33336.
15. Chelico, L., Sacho, E. J., Erie, D. A., and Goodman, M. F. (2008) J. Biol. Chem. 283, 13780-13791.
16. Holden, L. G., Prochnow, C., Chang, Y. P., Bransteitter, R., Chelico, L., Sen, U., Stevens, R. C., Goodman, M. F., and Chen, X. S. (2008) Nature 456, 121-124.
17. Furukawa, A., Nagata, T., Matsugami, A., Habu, Y., Sugiyama, R., Hayashi, F., Kobayashi, N., Yokoyama, S., Takaku, H., and Katahira, M. (2009) EMBO J. 28, 440-451.
18. Harjes, E., Gross, P. J., Chen, K. M., Lu, Y., Shindo, K., Nowarski, R., Gross, J. D., Kotler, M., Harris, R. S., and Matsuo, H. (2009) J. Mol. Biol. 389, 819-832.
19. Prochnow, C., Bransteitter, R., Klein, M. G., Goodman, M. F., and Chen, X. S. (2007) Nature 445, 447-451.
20. Philo, J. S. (2000) Anal. Biochem. 279, 151-163.
21. Philo, J. S. (2006) Anal. Biochem. 354, 238-246.
22. Schuck, P. (2000) Biophys. J. 78, 1606-1619.
23. Lebowitz, J., Lewis, M. S., and Schuck, P. (2002) Protein Sci. 11, 2067-2079.
24. Schuck, P. (2003) Anal. Biochem. 320, 104-124.
25. Hayes, D. B., Laue, T. M., and Philo, J. (2006) Sedimentation Interpretation Program , version 1.09, University of New Hampshire, Durham, NH.