A small molecule fusion inhibitor of dengue virus

Antiviral Research

Volumn 84, Issue 3, 2009, Pages 260-266

  Poh, Mee Kian ^a,b,c   Yip, Andy ^a   Zhang, Summer ^a   Priestle, John P ^e   Ma, Ngai Ling ^a   Smit, Jolanda M ^d   Wilschut, Jan ^d   Shi, Pei Yong ^a   Wenk, Markus R ^b,c   Schul, Wouter ^a  

^a NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antiviral; Dengue virus; Fusion inhibitor

Indexed keywords

ANTIVIRUS AGENT; LIPOSOME; NITD 448; PROPIDIUM IODIDE; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; COMPUTER ANALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DENGUE VIRUS; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; IC 50; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; VIRUS CELL INTERACTION; VIRUS ENTRY; VIRUS LOAD;

AEDES; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CRICETINAE; DENGUE VIRUS; MICROBIAL SENSITIVITY TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; SMALL MOLECULE LIBRARIES; VIRAL ENVELOPE PROTEINS; VIRUS INTERNALIZATION;

DENGUE VIRUS;

EID: 70449521008     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2009.09.011     Document Type: Article

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