In vitro and in vivo genotoxicity tests on fullerene C60 nanoparticles

Toxicology Letters

Volumn 191, Issue 2-3, 2009, Pages 289-296

  Shinohara, Naohide ^a   Matsumoto, Kyomu ^b   Endoh, Shigehisa ^a   Maru, Junko ^a   Nakanishi, Junko ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b INSTITUTE OF ENVIRONMENTAL TOXICOLOGY   (Japan)

Author keywords

Bacterial reverse mutation test; Chromosomal aberration test; Fullerene C60; Irradiation; Micronucleus test

Indexed keywords

CARBOXYMETHYLCELLULOSE; FULLERENE C60; FULLERENE DERIVATIVE; NANOPARTICLE; POLYSORBATE 80; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BACTERIAL STRAIN; CHINESE HAMSTER; CHROMOSOME ABERRATION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; METABOLIC ACTIVATION; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SALMONELLA TYPHIMURIUM; TOXICITY TESTING;

ANIMALS; CARBOXYMETHYLCELLULOSE SODIUM; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; DARKNESS; ESCHERICHIA COLI; FULLERENES; LIGHT; MICE; MICE, INBRED ICR; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; NANOPARTICLES; POLYSORBATES; SALMONELLA TYPHIMURIUM; SUSPENSIONS;

BACTERIA (MICROORGANISMS); CRICETULUS GRISEUS; ESCHERICHIA COLI; MUS; SALMONELLA TYPHIMURIUM;

EID: 70449519042     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.09.012     Document Type: Article

References (41)

1. Alargova R.G., Deguchi S., and Tsujii K. Stable colloidal dispersions of fullerenes in polar organic solvents. J. Am. Chem. Soc. 123 (2001) 10460-10467
2. Ames B.N., McCann J., and Yamasaki E. Methods for detecting carcinogens and mutagens with Salmonella/mammalian-microsome mutagenicity test. Mutat. Res. 31 (1975) 347-364
3. 60 embedded in gamma-cyclodextrin-a water-soluble fullerene. J. Chem. Soc. Chem. Commun. 8 (1992) 604-606
4. 60. J. Phys. Chem. 95 (1991) 11-12
5. 60 and raw soot from fullerene production on alveolar macrophages and macrophage-like cells in vitro. Exp. Toxicol. Pathol. 48 (1996) 508-511
6. Boutorine A.S., Tokuyama H., Takasugi M., Isobe H., Nakamura E., and Helene C. Fullerene-oligonucleotide conjugates-photoinduced sequence-specific DNA cleavage. Angew. Chem.-Int. 33 (1994) 2462-2465
7. Brant J.A., Labille J., Bottero J.Y., and Wiesner M.R. Characterizing the impact of preparation method on fullerene cluster structure and chemistry. Langmuir 22 (2006) 3878-3885
8. Brunauer S., Emmett P.H., and Teller E. Adsorption of gases in multimolecular layers. J. Am. Chem. Soc. 60 (1938) 309-319
9. Collins A.R., Ma A.G., and Duthie S.J. The kinetics of repair of oxidative DNA damage (strand breaks and oxidized pyrimidines) in human cells. Mutat. Res. 336 (1995) 69-77
10. Deguchi S., Alargova R.G., and Tsujii K. Stable dispersions of fullerenes, C60 and C70, in water: preparation and characterization. Langmuir 17 (2001) 6013-6017
11. Department of Labor, Safety, and Health, Industrial Health Division. Mutagenicity Test in Industrial Safety and Health Law: Test Guideline and GLP [in Japanese] (1995), Japan Industrial Safety and Health Association pp. 61-63
12. Dhawan A., Taurozzi J.S., Pandey A.K., Shan W.Q., Miller S.M., Hashsham S.A., and Tarabara V.V. Stable colloidal dispersions of C-60 fullerenes in water: evidence for genotoxicity. Environ. Sci. Technol. 40 (2006) 7394-7401
13. Fortner J.D., Lyon D.Y., Sayes C.M., Boyd A.M., Falkner J.C., Hotze E.M., Alemany L.B., Tao Y.J., Guo W., Ausman K.D., Colvin V.L., and Hughes J.B. C-60 in water: nanocrystal formation and microbial response. Environ. Sci. Technol. 39 (2005) 4307-4316
14. Gatehouse D., Haworth S., Cebula T., Gocke E., Kier L., Matsushima T., Melcion C., Nohmi T., Otha T., Venitt S., and Zeiger E. Recommendations for the performance of bacterial mutation assays. Mutat. Res. 312 (1994) 217-233
15. Gharbi N., Pressac M., Hadchouel M., Szwarc H., Wilson S.R., and Moussa F. [60]Fullerene is a powerful antioxidant in vivo with no acute or subacute toxicity. Nano Lett. 5 (2005) 2578-2585
16. Gonzales L., Lison D., and Kirsch-Volders M. Genotoxicity of engineered nanomaterials: A critical review. Nanotoxicology 2 (2008) 252-273
17. 60 fullerene derivatives. Acc. Chem. Res. 33 (2000) 695-703
18. Henry T.B., Menn F.M., Fleming J.T., Wilgus J., Compton R.N., and Sayler G.S. Attributing effects of aqueous C-60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression. Environ. Health Perspect. 115 (2007) 1059-1065
19. 60 in alcohols and alkanes. Carbon 34 (1996) 627-631
20. Hotze E.M., Labille J., Alvarez P., and Wiesner M.R. Mechanisms of photochemistry and reactive oxygen production by fullerene suspensions in water. Environ. Sci. Technol. 42 (2008) 4175-4180
21. Jia G., Wang H.F., Yan L., Wang X., Pei R.J., Yan T., Zhao Y.L., and Guo X.B. Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene. Environ. Sci. Technol. 39 (2005) 1378-1383
22. Kolosnjaj, J., Szwarc, H., Moussa, F., 2007. Toxicity studies of fullerenes and derivatives. Advances in Experimental Medicine and Biology, vol. 620 (Bio-applications of nanoparticles), pp. 168-180.
23. Landsiedel R., Kapp M.D., Schulz M., Wiench K., and Oesch F. Genotoxicity investigations on nanomaterials: Methods, preparation and characterization of test material, potential artifacts and limitations-Many questions, some answers. Mut. Res.-Rev. Mu. Res. 681 (2009) 241-258
24. Manolova N., Rashkov I., Beguin F., and Vandamme H. Amphiphilic derivatives of fullerenes formed by polymer modification. J. Chem. Soc. Chem. Commun. 23 (1993) 1725-1727
25. Markovic Z., Todorovic-Markovic B., Kleut D., Nikolic N., Vranjes-Djuric S., Misirkic M., Vucicevic L., Janjetovic K., Isakovic A., Harhaji L., Babic-Stojic B., Dramicanin M., and Trajkovic V. The mechanism of cell-damaging reactive oxygen generation by colloidal fullerenes. Biomaterials 28 (2007) 5437-5448
26. Mchedlov-Petrossyan N.O., Klochkov V.K., and Andrievsky G.V. Colloidal dispersions of fullerene C-60 in water: some properties and regularities of coagulation by electrolytes. J. Chem. Soc. Faraday Trans. 93 (1997) 4343-4346
27. Ministry of Economy, Trade, and Industry (METI), Japan. A Revision of the Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances (2003)
28. 60 carboxyfullerene exerts a protective activity against oxidative stress-induced apoptosis in human peripheral blood mononuclear cells. Biochem. Biophys. Res. Commun. 277 (2000) 711-717
29. Mori T., Takada H., Ito S., Matsubayashi K., Miwa N., and Sawaguchi T. Preclinical studies on safety of fullerene upon acute oral administration and evaluation for no mutagenesis. Toxicology 225 (2006) 48-54
30. Organization for Economic Co-operation and Development (OECD). OECD Guideline for the Testing of Chemicals: Mammalian Erythrocyte Micronucleus Test, No. 474 (1997)
31. 60 in a variety of solvents. J. Phys. Chem. 97 (1993) 3379-3383
32. 60 in aquatic organism. Environ. Sci. 21 (2008) 53-62
33. 60-generated singlet oxygen dependent formation of lipid peroxides. Carcinogenesis 17 (1996) 2163-2169
34. 60 nanoparticles in the brains of Cyprinus carpio?. Environ. Sci. Technol. 43 (2009) 948-953
35. Takahashi K., and Okuda Y. Acute toxicity test. In: Shirasu Y., and Matsuoka O. (Eds). Environmental Toxicology: Methods and Safety Evaluation [in Japanese] (1975), Softscience Ltd., Tokyo
36. Tatsuishi T., Oyama Y., Iwase K., Yamaguchi J., Kobayashi M., Nishimura Y., Kanada A., and Hirama S. Polysorbate 80 increases the susceptibility to oxidative stress in rat thymocytes. Toxicology 207 (2005) 7-14
37. Tokuyama H., Yamago S., Nakamura E., Shiraki T., and Sugiura Y. Photoinduced biochemical-activity of fullerene carboxylic-acid. J. Am. Chem. Soc. 115 (1993) 7918-7919
38. 60 on the chondrogenesis in rat embryonic limb bud cell culture system. Biochem. Biophys. Res. Commun. 206 (1995) 885-894
39. Watanabe-Akanuma M., and Ohta T. Inhibitory effects of NADH/NADPH in S9 mix on photo-mutagenicity of thiabendazole following UVA-irradiation in E. coli. Environ. Mutagen Res. 27 (2005) 7-12
40. Xu A., Chai Y., and Hei T.K. Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells. Part. Fibre Toxicol. 6 3 (2009) 1-13
41. Yamakoshi Y.N., Yagami T., Sueyoshi S., and Miyata N. Acridine adduct of [60]fullerene with enhanced DNA-cleaving activity. J. Org. Chem. 61 (1996) 7236-7237