Preclinical studies on safety of fullerene upon acute oral administration and evaluation for no mutagenesis

Toxicology

Volumn 225, Issue 1, 2006, Pages 48-54

  Mori, Tomohisa ^a   Takada, Hiroya ^b   Ito, Shinobu ^a   Matsubayashi, Kenji ^b   Miwa, Nobuhiko ^c   Sawaguchi, Toshiko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b MITSUBISHI CORPORATION   (Japan)

^c PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

Author keywords

Acute toxicity; Ames test; Chromosomal aberrations; Fullerenes; Genetic damage; Genotoxicity

Indexed keywords

FULLERENE; S 9;

ACUTE TOXICITY; AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BODY WEIGHT; CELL CULTURE; CHINESE HAMSTER; CONTROLLED STUDY; DRUG FATALITY; DRUG SAFETY; ESCHERICHIA COLI; FEMALE; GENE MUTATION; GENETIC DAMAGE; GENOTOXICITY; LD 50; LUNG ALVEOLUS CELL; MALE; MUTAGEN TESTING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; STRUCTURAL CHROMOSOME ABERRATION;

ADMINISTRATION, ORAL; ANIMALS; CELL LINE; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; DRUG EVALUATION, PRECLINICAL; ESCHERICHIA COLI; FEMALE; FULLERENES; MALE; MUTAGENICITY TESTS; MUTATION; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); CRICETULUS GRISEUS; ESCHERICHIA COLI; MAMMALIA; SALMONELLA TYPHIMURIUM;

EID: 33745742443     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.05.001     Document Type: Article

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