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Volumn 27, Issue 4, 2009, Pages 465-469

Targeted therapies in inflammatory bowel disease

Author keywords

Genome wide association studies; Inflammatory bowel disease, pathogenesis; Targeted therapies

Indexed keywords

ANTIGEN; ANTIINFLAMMATORY AGENT; CLAUDIN 2; CLAUDIN 5; CLAUDIN 8; GAMMA INTERFERON; GLUTAMINE; INFLIXIMAB; INTERLEUKIN 13; MESALAZINE; PROBIOTIC AGENT; QUERCETIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; ZINC;

EID: 70449485061     PISSN: 02572753     EISSN: None     Source Type: Journal    
DOI: 10.1159/000233284     Document Type: Review
Times cited : (21)

References (30)
  • 3
    • 0034754480 scopus 로고    scopus 로고
    • Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway
    • Lugering A, Schmidt M, Lugering N, Pauels HG, Domschke W, Kucharzik T: Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway. Gastroenterology 2001; 121: 1145-1157.
    • (2001) Gastroenterology , vol.121 , pp. 1145-1157
    • Lugering, A.1    Schmidt, M.2    Lugering, N.3    Pauels, H.G.4    Domschke, W.5    Kucharzik, T.6
  • 4
    • 34147211616 scopus 로고    scopus 로고
    • Te Velde AA, ten Cate FJ, et al: Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease
    • Van den Brande JM, Koehler TC, Zelinkova Z, Bennink RJ, te Velde AA, ten Cate FJ, et al: Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease. Gut 2007; 56: 509-517.
    • (2007) Gut , vol.56 , pp. 509-517
    • Van Den Brande, J.M.1    Koehler, T.C.2    Zelinkova, Z.3    Bennink, R.J.4
  • 7
    • 4344700784 scopus 로고    scopus 로고
    • Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor-- antibody treatment
    • Zeissig S, Bojarski C, Buergel N, Mankertz J, Zeitz M, Fromm M, et al: Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor-- antibody treatment. Gut 2004; 53: 1295-1302.
    • (2004) Gut , vol.53 , pp. 1295-1302
    • Zeissig, S.1    Bojarski, C.2    Buergel, N.3    Mankertz, J.4    Zeitz, M.5    Fromm, M.6
  • 8
    • 0028861975 scopus 로고
    • Antibodies to interleukin-12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W: Antibodies to interleukin-12 abrogate established experimental colitis in mice. J Exp Med 1995; 182: 1281-1290.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 10
    • 8344284998 scopus 로고    scopus 로고
    • Antibody for active Crohn's disease
    • antibody for active Crohn's disease. N Engl J Med 2004; 351: 2069-2079.
    • (2004) N Engl J Med , vol.351 , pp. 2069-2079
  • 11
    • 33845340501 scopus 로고    scopus 로고
    • A genomewide association study identifies IL-23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al: A genomewide association study identifies IL-23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-1463.
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3    Rioux, J.D.4    Silverberg, M.S.5    Daly, M.J.6
  • 12
    • 34247560627 scopus 로고    scopus 로고
    • IL- 23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
    • Tremelling M, Cummings F, Fisher SA, Mansfield J, Gwilliam R, Keniry A, et al: IL- 23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology 2007; 132: 1657-1664.
    • (2007) Gastroenterology , vol.132 , pp. 1657-1664
    • Tremelling, M.1    Cummings, F.2    Fisher, S.A.3    Mansfield, J.4    Gwilliam, R.5    Keniry, A.6
  • 13
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, et al: Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13: 715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6
  • 14
    • 0141835046 scopus 로고    scopus 로고
    • Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
    • Becker C, Wirtz S, Blessing M, Pirhonen J, Strand D, Bechthold O, et al: Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. J Clin Invest 2003; 112: 693-706.
    • (2003) J Clin Invest , vol.112 , pp. 693-706
    • Becker, C.1    Wirtz, S.2    Blessing, M.3    Pirhonen, J.4    Strand, D.5    Bechthold, O.6
  • 15
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor ROR- t directs the differentiation program of proinflammatory IL-17+ T-helper cells
    • Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, et al: The orphan nuclear receptor ROR- t directs the differentiation program of proinflammatory IL-17+ T-helper cells. Cell 2006; 126: 1121-1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6
  • 16
    • 33747089041 scopus 로고    scopus 로고
    • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
    • Uhlig HH, McKenzie BS, Hue S, Thompson C, Joyce-Shaikh B, Stepankova R, et al: Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 2006; 25: 309-318.
    • (2006) Immunity , vol.25 , pp. 309-318
    • Uhlig, H.H.1    McKenzie, B.S.2    Hue, S.3    Thompson, C.4    Joyce-Shaikh, B.5    Stepankova, R.6
  • 17
    • 33750530394 scopus 로고    scopus 로고
    • IL-23 plays a key role in Helicobacter hepaticus -induced T-cell-dependent colitis
    • Kullberg MC, Jankovic D, Feng CG, Hue S, Gorelick PL, McKenzie BS, et al: IL-23 plays a key role in Helicobacter hepaticus -induced T-cell-dependent colitis. J Exp Med 2006; 203: 2485-2494.
    • (2006) J Exp Med , vol.203 , pp. 2485-2494
    • Kullberg, M.C.1    Jankovic, D.2    Feng, C.G.3    Hue, S.4    Gorelick, P.L.5    McKenzie, B.S.6
  • 18
  • 19
    • 33846036986 scopus 로고    scopus 로고
    • IL-23: A master regulator in Crohn disease
    • Neurath MF: IL-23: A master regulator in Crohn disease. Nat Med 2007; 13: 26-28.
    • (2007) Nat Med , vol.13 , pp. 26-28
    • Neurath, M.F.1
  • 20
    • 0035199921 scopus 로고    scopus 로고
    • MAdCAM mediates lymphocyte- endothelial cell adhesion in a murine model of chronic colitis
    • Shigematsu T, Specian RD, Wolf RE, Grisham MB, Granger DN: MAdCAM mediates lymphocyte- endothelial cell adhesion in a murine model of chronic colitis. Am J Physiol 2001; 281:G1309-G1315.
    • (2001) Am J Physiol , vol.281
    • Shigematsu, T.1    Specian, R.D.2    Wolf, R.E.3    Grisham, M.B.4    Granger, D.N.5
  • 21
    • 0033815802 scopus 로고    scopus 로고
    • Amelioration of murine experimental colitis by inhibition of mucosal addressin cell adhesion molecule-1
    • Kato S, Hokari R, Matsuzaki K, Iwai A, Kawaguchi A, Nagao S, et al: Amelioration of murine experimental colitis by inhibition of mucosal addressin cell adhesion molecule-1. J Pharmacol Exp Ther 2000; 295: 183-189.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 183-189
    • Kato, S.1    Hokari, R.2    Matsuzaki, K.3    Iwai, A.4    Kawaguchi, A.5    Nagao, S.6
  • 24
    • 0033546663 scopus 로고    scopus 로고
    • The effect of anti-- 4 integrin antibody on brain lesion activity in MS. the UK Antegren Study Group
    • Tubridy N, Behan PO, Capildeo R, Chaudhuri A, Forbes R, Hawkins CP, et al: The effect of anti-- 4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group. Neurology 1999; 53: 466-472.
    • (1999) Neurology , vol.53 , pp. 466-472
    • Tubridy, N.1    Behan, P.O.2    Capildeo, R.3    Chaudhuri, A.4    Forbes, R.5    Hawkins, C.P.6
  • 25
    • 22844439662 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon-- 1 a for multiple sclerosis
    • Kleinschmidt-DeMasters BK, Tyler KL: Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon-- 1 a for multiple sclerosis. N Engl J Med 2005; 353: 369-374.
    • (2005) N Engl J Med , vol.353 , pp. 369-374
    • Kleinschmidt-Demasters, B.K.1    Tyler, K.L.2
  • 26
    • 22844445230 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
    • Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D: Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med 2005; 353: 375-381.
    • (2005) N Engl J Med , vol.353 , pp. 375-381
    • Langer-Gould, A.1    Atlas, S.W.2    Green, A.J.3    Bollen, A.W.4    Pelletier, D.5
  • 27
    • 22844445587 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease
    • Van Assche G, Van Ranst M, Sciot R, Dubois B, Vermeire S, Noman M, et al: Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N Engl J Med 2005; 353: 362-368.
    • (2005) N Engl J Med , vol.353 , pp. 362-368
    • Van Assche, G.1    Van Ranst, M.2    Sciot, R.3    Dubois, B.4    Vermeire, S.5    Noman, M.6
  • 28
    • 22844438117 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy and natalizumab - Unforeseen consequences
    • Berger JR, Koralnik IJ: Progressive multifocal leukoencephalopathy and natalizumab - unforeseen consequences. N Engl J Med 2005; 353: 414-416.
    • (2005) N Engl J Med , vol.353 , pp. 414-416
    • Berger, J.R.1    Koralnik, I.J.2
  • 29
    • 4344600302 scopus 로고    scopus 로고
    • A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy
    • Du Pasquier RA, Kuroda MJ, Zheng Y, Jean- Jacques J, Letvin NL, Koralnik IJ: A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy. Brain 2004; 127: 1970-1978.
    • (2004) Brain , vol.127 , pp. 1970-1978
    • Du Pasquier, R.A.1    Kuroda, M.J.2    Zheng, Y.3    Jean- Jacques, J.4    Letvin, N.L.5    Koralnik, I.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.