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Volumn 342, Issue 11, 2009, Pages 640-650
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Synthesis of 2-fluoro N10-substituted acridones and their cytotoxicity studies in sensitive and resistant cancer cell lines and their DNA intercalation studies
a,b
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Author keywords
Acridone; Mitoxantrone; Multidrug resistance (MDR); P glycoprotein
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Indexed keywords
0 [3' [N METHYLPIPERAZINO]PROPYL] 2 FLUOROACRIDONE;
10 (3' CHLOROPROPYL) 2 FLUOROACRIDONE;
10 (3' N CHLOROBUTYL) 2 FLUOROACRIDONE;
10 (3' N PYRROLIDINOBUTYL) 2 FLUOROACRIDONE;
10 (4' N [(BETA HYDROXYETHYL)PIPERAZINO]BUTYL) 2 FLUOROACRIDONE;
10 (4' N MORPHOLINOBUTYL) 2 FLUOROACRIDONE;
10 (4' N PIPERIDINOBUTYL) 2 FLUOROACRIDONE;
10 [3' (N DIETHYLAMINO) PROYL] 2 FLUOROACRIDONE;
10 [3' (N DIETHYLAMINO)BUTYL] 2 FLUOROACRIDONE;
10 [3' [N BIS(HYDROXYETHYL)AMINO]BUTYL] 2 FLUOROACRIDONE;
10 [3' [N BIS(HYDROXYETHYL)AMINO]PROPYL] 2 FLUOROACRIDONE;
10 [3' N [(BETA HYDROXYETHYL)PIPERAZINO]PROPYL] 2 FLUOROACRIDONE;
10 [3' N MORPHOLINOPROPYL] 2 FLUOROACRIDONE;
10 [3' N PIPERIDINOPROPYL] 2 FLUOROACRIDONE;
10 [3' N PYRROLIDINOPROPYL] 2 FLUOROACRIDONE;
10 [4' N (METHYLPIPERAZINO) BUTYL] 2 FLUOROACRIDONE;
ACRIDONE DERIVATIVE;
ANTINEOPLASTIC AGENT;
BREAST CANCER RESISTANCE PROTEIN;
DOXORUBICIN;
GLYCOPROTEIN P;
IMIDACRINE;
MITOXANTRONE;
MULTIDRUG RESISTANCE PROTEIN;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BINDING AFFINITY;
BREAST CANCER;
CANCER RESISTANCE;
CARBON NUCLEAR MAGNETIC RESONANCE;
CELL STRAIN HEK293;
CELL STRAIN MCF 7;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG DNA BINDING;
DRUG POTENCY;
DRUG STRUCTURE;
FEMALE;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
KIDNEY CANCER;
LEUKEMIA;
LIPOPHILICITY;
LUNG CANCER;
LUNG NON SMALL CELL CANCER;
MALE;
MELANOMA;
OVARY CANCER;
PRIORITY JOURNAL;
PROSTATE CANCER;
PROTEIN EXPRESSION;
PROTON NUCLEAR MAGNETIC RESONANCE;
SUBSTITUTION REACTION;
ACRIDONES;
CELL LINE, TUMOR;
DRUG RESISTANCE, NEOPLASM;
DRUG SCREENING ASSAYS, ANTITUMOR;
HUMANS;
INTERCALATING AGENTS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 70449450120
PISSN: 03656233
EISSN: 15214184
Source Type: Journal
DOI: 10.1002/ardp.200900046 Document Type: Article |
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Times cited : (30)
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References (22)
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