-
1
-
-
0028155964
-
A 190 k protein overexpressed in non-P-glycoprotein containing MDR cells and its relation to the MRP gene
-
Barrand MA, Heppel-Parton AC, Wright KA, Rabbits PH and Twentyman PR (1994) A 190k protein overexpressed in non-P-glycoprotein containing MDR cells and its relation to the MRP gene. J Natl Cancer Inst 86: 110-117
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 110-117
-
-
Barrand, M.A.1
Heppel-Parton, A.C.2
Wright, K.A.3
Rabbits, P.H.4
Twentyman, P.R.5
-
2
-
-
0030069428
-
Reversible labeling of a chemosensitizer binding domain of P-glycoprotein with a novel 1,4-dihydropyridine drug transport inhibitor
-
Boer R, Dichil M, Borchers C, Ulrich WR, Marecek JF, Prestwich GD, Glossmann H and Striessing J (1996) Reversible labeling of a chemosensitizer binding domain of P-glycoprotein with a novel 1,4-dihydropyridine drug transport inhibitor. Biochemistry 35: 1387-1396
-
(1996)
Biochemistry
, vol.35
, pp. 1387-1396
-
-
Boer, R.1
Dichil, M.2
Borchers, C.3
Ulrich, W.R.4
Marecek, J.F.5
Prestwich, G.D.6
Glossmann, H.7
Striessing, J.8
-
3
-
-
0030921564
-
The functional purification of P-glycoprotein is dependent on maintenance of a lipid protein inter-face
-
Callaghan R, Berridge G. Ferry DR and Higgins CF (1997) The functional purification of P-glycoprotein is dependent on maintenance of a lipid protein inter-face. Biochem Biophys Acta Biomembranes 1328: 109-124
-
(1997)
Biochem Biophys Acta Biomembranes
, vol.1328
, pp. 109-124
-
-
Callaghan, R.1
Berridge, G.2
Ferry, D.R.3
Higgins, C.F.4
-
4
-
-
0028024166
-
Prevalence of multidrug resistance related to activation of the mdrl gene in human sarcoma mutants derived by single-step doxorubicin selection
-
Chen G, Jaffrezou J-P, Fleming WH, Duran GE and Sikie BI (1994) Prevalence of multidrug resistance related to activation of the mdrl gene in human sarcoma mutants derived by single-step doxorubicin selection. Cancer Res 54: 4980-4987
-
(1994)
Cancer Res
, vol.54
, pp. 4980-4987
-
-
Chen, G.1
Jaffrezou, J.-P.2
Fleming, W.H.3
Duran, G.E.4
Sikie, B.I.5
-
5
-
-
0027095653
-
Over-expression of a transporter gene in a multidrug resistant human lung cancer cell line
-
Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz E, Duncan AMV and Deeley RG (1992) Over-expression of a transporter gene in a multidrug resistant human lung cancer cell line. Science 258: 1650-1653
-
(1992)
Science
, vol.258
, pp. 1650-1653
-
-
Cole, S.P.C.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.8
Duncan, A.M.V.9
Deeley, R.G.10
-
6
-
-
0030039548
-
Regulation of P-glycoprotein 1 and 2 gene expression and protein activity in two MCF 7/Dox cell line subclones
-
Davies R, Budworth J, Riley J, Snowden R, Gescher A and Gant T (1996) Regulation of P-glycoprotein 1 and 2 gene expression and protein activity in two MCF 7/Dox cell line subclones. Br J Cancer 73: 307-315
-
(1996)
Br J Cancer
, vol.73
, pp. 307-315
-
-
Davies, R.1
Budworth, J.2
Riley, J.3
Snowden, R.4
Gescher, A.5
Gant, T.6
-
7
-
-
0030924052
-
Evidence for two non-identical drug-interaction sites in the human P glycoprotein
-
Day S, Ramachandra M, Pastan I, Gottesman MM and Ambudkar SV (1997) Evidence for two non-identical drug-interaction sites in the human P glycoprotein. Proc Natl Acad Sci USA 94: 10594-10599
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10594-10599
-
-
Day, S.1
Ramachandra, M.2
Pastan, I.3
Gottesman, M.M.4
Ambudkar, S.V.5
-
8
-
-
0020084268
-
Validation and statistical analysis of a computer modelling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes
-
DeLean A, Hancock AA and Lefkowitz RJ (1981) Validation and statistical analysis of a computer modelling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. Mol Pharmacol 21: 5-16
-
(1981)
Mol Pharmacol
, vol.21
, pp. 5-16
-
-
DeLean, A.1
Hancock, A.A.2
Lefkowitz, R.J.3
-
9
-
-
0024329881
-
The biochemistry of P-glycoprotein mediated multidrug resistance
-
Endicott JA and Ling V (1989) The biochemistry of P-glycoprotein mediated multidrug resistance. Annu Rev Biochem 58: 137-171
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
10
-
-
0026475310
-
P-glycoprotein possesses a 1,4-dihydropyridine-selective drug acceptor site which is allosterically coupled to a vinca alkaloid-selective binding site
-
Ferry DR, Russell MA and Cullen MH (1992) P-glycoprotein possesses a 1,4-dihydropyridine-selective drug acceptor site which is allosterically coupled to a vinca alkaloid-selective binding site. Biochem Biophys Res Commun 188: 440-445
-
(1992)
Biochem Biophys Res Commun
, vol.188
, pp. 440-445
-
-
Ferry, D.R.1
Russell, M.A.2
Cullen, M.H.3
-
11
-
-
0009508504
-
3H]-taxol binds to a drug acceptor site which is allosterically coupled to the vinblastine-selective site of P-glycoprotein
-
3H]-Taxol binds to a drug acceptor site which is allosterically coupled to the vinblastine-selective site of P-glycoprotein. Proc Am Assoc Cancer Res 35: 348
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
, pp. 348
-
-
Ferry, D.R.1
Russell, M.A.2
Kerr, D.J.3
-
15
-
-
0000004701
-
Phase 1 and pharmacokinetic (PK) study targeting a 500 ng/ml plasma concentration of the potent multidrug resistance (MDR) modulator GF120918 (GF) with doxorubicin (DOX) in patients with advanced solid tumors
-
Ferry D, Moore M, Bartlett NL, Fyfe D, Oza G, Fracasso PM, Kersey K, Wissel PS, Jewell RC and Paul EM (1998) Phase 1 and pharmacokinetic (PK) study targeting a 500 ng/ml plasma concentration of the potent multidrug resistance (MDR) modulator GF120918 (GF) with doxorubicin (DOX) in patients with advanced solid tumors. Proc Am Soc Clin Oncol 17: 240a
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Ferry, D.1
Moore, M.2
Bartlett, N.L.3
Fyfe, D.4
Oza, G.5
Fracasso, P.M.6
Kersey, K.7
Wissel, P.S.8
Jewell, R.C.9
Paul, E.M.10
-
16
-
-
0025007511
-
Pharmacology of drugs that alter multidrug resistance in cancer
-
Ford JM and Hait WN (1990) Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 42(3): 155-199
-
(1990)
Pharmacol Rev
, vol.42
, Issue.3
, pp. 155-199
-
-
Ford, J.M.1
Hait, W.N.2
-
17
-
-
0024806599
-
Reversal by cefoperazone of resistance to etoposide, doxorubicin, and vinblastine in multidrug resistant human sarcoma line
-
Gosland MP, Lum BL and Sikic BI (1989) Reversal by cefoperazone of resistance to etoposide, doxorubicin, and vinblastine in multidrug resistant human sarcoma line. Cancer Res 49: 6901-6905
-
(1989)
Cancer Res
, vol.49
, pp. 6901-6905
-
-
Gosland, M.P.1
Lum, B.L.2
Sikic, B.I.3
-
18
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman MM and Pastan P (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62: 385-427
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, P.2
-
19
-
-
0022352607
-
Multidrug (pleiotropic) resistance in doxorubicin selected variants of the human sarcoma cell line MES-SA
-
Harker WG and Sikic BI (1985) Multidrug (pleiotropic) resistance in doxorubicin selected variants of the human sarcoma cell line MES-SA. Cancer Res 45: 4091-4096
-
(1985)
Cancer Res
, vol.45
, pp. 4091-4096
-
-
Harker, W.G.1
Sikic, B.I.2
-
20
-
-
0020559955
-
Devlopment and characterization of a human sarcoma cell line, MES SA, sensitive to multiple drugs
-
Harker WG, MacKintosh FR and Sikic BI (1983) Devlopment and characterization of a human sarcoma cell line, MES SA, sensitive to multiple drugs. Cancer Res 43: 4943-4950
-
(1983)
Cancer Res
, vol.43
, pp. 4943-4950
-
-
Harker, W.G.1
MacKintosh, F.R.2
Sikic, B.I.3
-
21
-
-
0027524642
-
In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative
-
Hyafil F, Vergely C, Du VP and Grand PT (1993) In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res 53(19); 4595-4602
-
(1993)
Cancer Res
, vol.53
, Issue.19
, pp. 4595-4602
-
-
Hyafil, F.1
Vergely, C.2
Du, V.P.3
Grand, P.T.4
-
22
-
-
0028318223
-
Structurally distinct MDR modulators show specific pattern of reversal against P glycoproteins bearing unique mutations at serine (939/941)
-
Kajiji S, Dreslin JA, Grizzuti K and Gros P (1994) Structurally distinct MDR modulators show specific pattern of reversal against P glycoproteins bearing unique mutations at serine (939/941). Biochem 33(17): 5041-5048
-
(1994)
Biochem
, vol.33
, Issue.17
, pp. 5041-5048
-
-
Kajiji, S.1
Dreslin, J.A.2
Grizzuti, K.3
Gros, P.4
-
23
-
-
0000746057
-
P-glycoprotein has a drug acceptor site for 1,4-dihydropyridines which is localised on an intracellular domain
-
Malkhandi PJ, Ferry DR, Boer R and Kerr DJ (1995) P-glycoprotein has a drug acceptor site for 1,4-dihydropyridines which is localised on an intracellular domain. Proc Am Assoc Cancer Res 36; 332
-
(1995)
Proc Am Assoc Cancer Res
, vol.36
, pp. 332
-
-
Malkhandi, P.J.1
Ferry, D.R.2
Boer, R.3
Kerr, D.J.4
-
24
-
-
0026051296
-
P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high dose verapamil
-
Miller TP, Grogan TM, Dalton WS, Spier CM, Scheper RJ and Salmon SE (1991) P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high dose verapamil. J Clin Oncol 9: 17-24
-
(1991)
J Clin Oncol
, vol.9
, pp. 17-24
-
-
Miller, T.P.1
Grogan, T.M.2
Dalton, W.S.3
Spier, C.M.4
Scheper, R.J.5
Salmon, S.E.6
-
25
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
26
-
-
4243315451
-
Phase I and pharmacokinetic (PK) study targeting a 100 ng/ml plasma concentration of the potent multidrug resistance (MDR) modulator GF120918 (GF) with doxorubicin (DOX) in patients with advanced solid tumors
-
Planting A, van der Gaast A, Sparreboom A, van der Burg MEL, de Boer M, Wissel PS, Jewell RC, Paul EM and Verweij J (1998) Phase I and pharmacokinetic (PK) study targeting a 100 ng/ml plasma concentration of the potent multidrug resistance (MDR) modulator GF120918 (GF) with doxorubicin (DOX) in patients with advanced solid tumors. Proc Am Soc Clin Oncol 17: 199a
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Planting, A.1
Van der Gaast, A.2
Sparreboom, A.3
Van der Burg, M.E.L.4
De Boer, M.5
Wissel, P.S.6
Jewell, R.C.7
Paul, E.M.8
Verweij, J.9
-
27
-
-
0025193531
-
Photosensitive labeling of a functional multidrug transporter in living drug resistant tumour cells
-
Raviv Y, Poland HB, Bruggermann EP, Pastan I and Gottesman MM (1990) Photosensitive labeling of a functional multidrug transporter in living drug resistant tumour cells. J Biol Chem 265: 3975-3980
-
(1990)
J Biol Chem
, vol.265
, pp. 3975-3980
-
-
Raviv, Y.1
Poland, H.B.2
Bruggermann, E.P.3
Pastan, I.4
Gottesman, M.M.5
-
28
-
-
0001580529
-
Transfer of proteins from SDS polyacrylamide gels to solid supports: Immunological detection of immobilized proteins (Western blotting)
-
Nolan C (ed), Cold Spring Harbor Laboratory Press: New York
-
Sambrook J, Fritsch EF and Maniatis T (1989). Transfer of proteins from SDS polyacrylamide gels to solid supports: immunological detection of immobilized proteins (Western blotting). In: Laboratory Cloning a Laboratory Manual, Nolan C (ed), pp. 18.60-18.75. Cold Spring Harbor Laboratory Press: New York
-
(1989)
Laboratory Cloning a Laboratory Manual
, pp. 1860-1875
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
29
-
-
0027466646
-
L 110 000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance
-
L 110 000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res 53: 1475-1479
-
(1993)
Cancer Res
, vol.53
, pp. 1475-1479
-
-
Scheper, R.J.1
Broxterman, H.J.2
Scheffer, G.L.3
Kaaijk, P.4
Dalton, W.S.5
Van Heijningen, T.H.M.6
Van Kalken, C.K.7
Slovak, M.L.8
De Vries, E.G.E.9
Van der Valk, P.10
Meijer, C.J.L.M.11
Pinedo, H.M.12
-
30
-
-
0022552877
-
Taxol-dependent mutants of chinese hamster ovary cells with alterations in alpha-tubulin and beta-tubulin
-
Schibler MJ and Cabral F (1986) Taxol-dependent mutants of chinese hamster ovary cells with alterations in alpha-tubulin and beta-tubulin. J Cell Biol 102: 1522-1531
-
(1986)
J Cell Biol
, vol.102
, pp. 1522-1531
-
-
Schibler, M.J.1
Cabral, F.2
-
31
-
-
0029061103
-
Reconstitution of drug transport by purified P-glycoprotein
-
Shupiro AB, Ling V and Doige CA (1995) Reconstitution of drug transport by purified P-glycoprotein. J Biol Chem 270: 16167-16175
-
(1995)
J Biol Chem
, vol.270
, pp. 16167-16175
-
-
Shupiro, A.B.1
Ling, V.2
Doige, C.A.3
-
32
-
-
0026634681
-
Modulation of multidrug resistant mycloma by cyclosporin
-
Sonneveld P, Duric BGM, Lokhorst HM, Marie J-P, Solbu G, Zittoun R., Lowenberg B and Nooler K (1992) Modulation of multidrug resistant mycloma by cyclosporin. Lancet 340: 255-258
-
(1992)
Lancet
, vol.340
, pp. 255-258
-
-
Sonneveld, P.1
Duric, B.G.M.2
Lokhorst, H.M.3
Marie, J.-P.4
Solbu, G.5
Zittoun, R.6
Lowenberg, B.7
Nooler, K.8
-
34
-
-
0030041652
-
Flow cytometric assay of modulation of P-glycoprotein function in whole blood by the multidrug resistance inhibitor GG918
-
Witherspoon SM, Emerson DL, Kerr BM, Lloyd TL, Dalton WS and Wissel PS (1996) Flow cytometric assay of modulation of P-glycoprotein function in whole blood by the multidrug resistance inhibitor GG918. Clin Cancer Res 2: 7-12
-
(1996)
Clin Cancer Res
, vol.2
, pp. 7-12
-
-
Witherspoon, S.M.1
Emerson, D.L.2
Kerr, B.M.3
Lloyd, T.L.4
Dalton, W.S.5
Wissel, P.S.6
|