A concise synthesis of ortho-iodobenzyl alcohols via addition of ortho-Iodophenyl grignard reagent to aldehydes and ketones

Synthesis

Volumn , Issue 16, 2009, Pages 2818-2824

  Cvengro, Alcohols Ján ^a   Stolz, Daniel ^a   Togni, Antonio ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Addition reactions; Benzyl alcohols; Grignard reactions; Hypervalent iodine compounds; Organometallic reagents

Indexed keywords

BENZYL ALCOHOLS; CONCISE SYNTHESIS; GRIGNARD REACTIONS; GRIGNARD REAGENT; HYPERVALENT IODINE; HYPERVALENT IODINE COMPOUNDS; ORGANOMETALLIC REAGENTS; POTENTIAL APPLICATIONS; TARGET COMPOUND;

ALDEHYDES; INDUSTRIAL CHEMICALS; IODINE; IODINE COMPOUNDS; KETONES; ORGANOMETALLICS; SYNTHESIS (CHEMICAL);

ADDITION REACTIONS;

(2 CHLOROPHENYL)(2 IODOPHENYL)METHANOL; (2 IODOPHENYL)(1 TRITYLPYRROLIDIN 2 YL)METHANOL; (2 IODOPHENYL)PHENYLMETHANOL; (3 BROMOPHENYL)(2 IODOPHENYL)METHANOL; (3,4 DIMETHOXYPHENYL)(2 IODOPHENYL)METHANOL; 1 (1 BENZYLPYRROLIDIN 2 YL) 1 (2 IODOPHENYL)ETHANOL; 1 (2 IODOPHENYL) 1 PHENYLETHANOL; 1 (2 IODOPHENYL)BUT 2 EN 1 OL; 1 (2 IODOPHENYL)CYCLOHEXANOL; 1 (2 IODOPHENYL)ETHANONE; 1 [3 [HYDROXY(2 IODOPHENYL)METHYL]PHENYL]ETHANONE; 1,1,1,3,3,3 HEXAFLUORO 2 (2 IODOPHENYL)PROPAN 2 OL; 2 (2 IODOPHENYL) 4 PHENYLBUTAN 2 OL; 2 (2 IODOPHENYL) 6 METHYLHEPT 5 EN 2 OL; 2 BROMO 1 (2 IODOPHENYL) 3 PHENYLPROP 2 EN 1 OL; 2 IODOBENZYL ALCOHOL DERIVATIVE; 2 IODOPHENYL GRIGNARD REAGENT; ALDEHYDE DERIVATIVE; BENZYL ALCOHOL DERIVATIVE; GRIGNARD REAGENT; IODINE DERIVATIVE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

CONTROLLED STUDY; REVIEW; SYNTHESIS;

EID: 70449413687     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1217406     Document Type: Review

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