Molecular modelling studies of some substitued 2-butylbenzimidazoles angiotensin II receptor antagonists as antihypertensive agents

Digest Journal of Nanomaterials and Biostructures

Volumn 4, Issue 4, 2009, Pages 843-856

  Sharma, M C ^a   Kohli, D V ^a   Chaturvedi, S C ^b   Sharma, Smita ^c  

^a DR H S GOUR UNIVERSITY   (India)

^b DEVI AHILYA UNIVERSITY   (India)

^c Chodhary Dilip Singh KanyaMahavidyla Bhind   (India)

Author keywords

2 butylbenzimidazole; Angiotensin II receptor; Antihypertensive agents; Docking; Losrtan; PLS; QSAR

Indexed keywords

EID: 70449120322     PISSN: None     EISSN: 18423582     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Hansch, C.; Fujita, J. Am. Chem. Soc. 86, 1616-1630. (1964).
2. X.J. Yao, J.P. Panaye, J.P. Doucet, R.S. Zhang, H.F. Chen, M.C. Liu, Z.D. Hu, B.T. Fan, J. Chem. Inf. Comput. Sci. 44 1257, 1266 (2004)
3. Jorgensen WL, Science 254 5034 954,(1991).
4. M. de Gasparo, K.J. Catt, T. Inagami, J.W. Wright, T. Unger, Pharmacol. Rev. 52, 415 (2000).
5. M. Stoll, T. Unger, Angiotensin and its AT2 receptor: new insights into an old system, Regul. Pept. 99 175 (2001).
6. Israili, Z. H., J. Hum. Hypertens. 14 (Suppl. 1), S73-S86 [2000]
7. Keiji Kubo, Yoshiyuki Inada, Yasuhisa Kohara, Yoshihiro Sugiura. Mami Ojima, Katsuhiko Itoh, Yeshivas Furukawa, Kohei Nishikawa, and Takehiko Naka J. Med. Chem. 36,1772-1784 (1993).
8. V-Life MDS 3.5, Molecular Design Suite, VLife Sciences Technologies, Pvt. Ltd. Pune, India, (2003).
9. A.K. Chakraborti, B. Gopalakrishnan, M.E. Sobhia, A. Malde, Eur. J. Med. Chem. 38, 975 (2003).
10. A. Coi, F.L. Fiamingo, O. Livi et al., Bioorg. Med. Chem. 17, 319 (2009).
11. A. Golbraikh, A. Tropsha, J. Comp. Aid. Molec. Des. 16, 357 (2002).
12. A. Golbraikh, J. Chem. Inf. Comput.Sci. 40, 414 (2000).
13. R. Guha, J.R. Serra, P.C. Jurs, J. Mol. Graph. Model 23, 1-14 (2004)
14. H. Kubinyi. Quant. Struct. Act. Relat., 13,285 (1994).
15. A. Patny, Prashant V. Desai, and Mitchell A. Avery, PROTEINS: Structure, Function, and Bioinformatics 65, 824-842 (2006).
16. Fierens, F. L. P.; Vanderbeyden, P. M. L.; Gaborik, Z.; LeMinb, T.; DeBacker, J. P.; Hunyady, L.; Ijzerman, A.; Vauquelin, G. J. RAAS, 1, 283 (2001).
17. Hjorth, S. A.; Schambye, H. T.; Greenlee, W. J.; Schwartz, T. W. J. Biol. Chem. 269, 30953, (1994).
18. Hunyady, L.; Balla, T.; Catt, K. J. Trends Pharmacol. Sci. 17, 135, (1996)
19. Miura, S. I.; Feng, Y. H.; Husain, A.; Karnik, S. S. J. Biol. Chem. 274, 7103 (1999).
20. Monnot, C.; Bihoreau, C.; Conchon, S.; Curnow, K. M.; Corvol, P.; Clauser, E. J. Biol. Chem. 271, 1507 (1996)
21. Nirula, V.; Zheng, W.; Sothinathan, R.; Sandberg, K. Br. J. Pharmacol.,119, 1505 (1996)
22. Noda, K.; Saad, Y.; Kinoshita, A.; Boyle, T. P.; Graham, R. M.; Husain, A.; Karnik, S. S. J. Biol. Chem 270, 2284 (1995).
23. Prendergast, K.; Adams, K.; Greenlee, W. J.; Nachbar, R.B.; Patchett, A. A.; Underwood, D. J. J. Comput. Aided Mol. Des., 8, 491 (1994).
24. Schambye, H. T.; Hjorth, S. A.; Weinstock, J.; Schwartzn, W. Mol. Pharmacol. 47, 425 (1995).
25. Wang, C.; Jayadev, S.; Escobedo, J. A. J. Biol. Chem. 270, 16677 (1995).
26. Zoumpoulakis, P.; Daliani, I.; Zervou, M.; Kyrikou, I.; Siapi, E.; Lamprinidis, G.; Mikros, E.; Mavromoustakos, T. Chem. Phys. Lip., 125, 13 [2003]
27. Ashton, W. T.; Cantone, C. L., Chang, L. L., Hutchins, S. M., Strelitz, R. A., Mcross, M., Chang R. S. L., Lotti, V. J., Faust, K. A., Chen, T., Bunting, P., Schorn, T. N., Kivlighn, S. D., Siegl, P. K. S. J. Med. Chem., 36, 591 (1993).
28. Datar, P. A.; Desai, P. V.; Coutinho, E. C. J. Chem. Inf. Comput. Sci, 44, 210 (2004)
29. Berrllini, G.; Cruciani, G.; Mannhold, R. J. Med. Chem., 48, 4389 (2005).
30. Tuccinardi, T.; Calderone, V.; Rapposelli, S.; Martinelli, A. J. Med. Chem. 49, 4305 (2006).