Purification, activity and sequence of angiotensin converting enzyme inhibitory peptide from aicalase hydroiysate of peanut flour

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 21, 2009, Pages 10102-10106

  Guang, Cuie ^a   Phillips, Robert D ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

ACE inhibitory peptides; Angiotensin I converting enzyme; Peanut protein

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PEPTIDE; SUBTILISIN;

ARTICLE; CHEMISTRY; FLOUR; HYDROLYSIS; ISOLATION AND PURIFICATION; METABOLISM; PEANUT; SEQUENCE ANALYSIS;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ARACHIS HYPOGAEA; FLOUR; HYDROLYSIS; PEPTIDES; PEPTIDYL-DIPEPTIDASE A; SEQUENCE ANALYSIS, PROTEIN; SUBTILISINS;

ARACHIS HYPOGAEA;

EID: 70449116398     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf901787e     Document Type: Article

References (17)

1. Wang, W.; Gonzalez de Mejia, E. A new frontier in soy bioactive peptides that may prevent age-related chronic diseases. Compr. Rev. Food Sci. Food Saf. 2005, 4, 63-78.
2. (2) Yust, M. M.; Pedroche, J.; Girón-Calle, J.; Alaiz, M.; Millán, F.; Vioque, J. Production of ACE inhibitory peptides by digestion of chickpea legumin with alcalase. Food Chem. 2003, 81, 363-369. (Pubitemid 36349466)
3. Pihlanto, A.; Akkanen, S.; Korhonen, H. J. ACE-inhibitory and antioxidant properties of potato (Solanum tuberosum). Food Chem. 2008, 109, 104-112.
4. Wu, J.; Ding, X. Characterization of inhibition and stability of soy-protein-derived angiotensin I-converting enzyme inhibitory peptides. Food Res. Int. 2002, 35, 367-375.
5. Chiang, W.; Tsou, M.; Tsai, Z.; Tsai, T. Angiotensin I-converting enzyme inhibitor derived from soy protein hydrolysate and produced by using membrane reactor. Food Chem. 2006, 98, 725-732.
6. Quist, E. E.; Phillips, R. D.; Saalia, F. K. Angiotensin converting enzyme inhibitory activity of proteolytic digests of peanut (Arachis hypogaea L.) flour. LWT; Food Sci. Technol. 2009, 42, 694-699.
7. Pedroche, J.; Yust, M. M.; Girón-Calle, J.; Alaiz, M.; Millán, F.; Vioque, J. Utilization of chickpea protein isolates for production of peptides with angiotensin I-converting enzyme (ACE)-inhibitory activity. J. Sci. Food Agric. 2002, 82, 960-965.
8. Guang, C.; Phillips, R. D. Application of a microplate kinetic assay to the determination of aingiotensin I converting enzyme inhibitory activities of Alcalase hydrolysates of peanut and cowpea flours. J. Food Compos. Anal., submitted for publication.
9. Matsui, T.; Li, C. H.; Osajima, Y. Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ. J. Pept. Sci. 1999, 5, 289-297.
10. Li, G.; Wan, J.; Le, G.; Shi, Y. Novel angiotensin I-converting enzyme inhibitory peptides isolated from Alcalase hydrolysate of mung bean protein. J. Pept. Sci. 2006, 12, 509-514.
11. Yang, Y.; Tao, G.; Liu, P.; Liu, J. Peptide with anigiotensin I-converting enzyme inhibitory activity from hydrolyzed corn gluten meal. J. Agric. Food Chem. 2007, 55, 7891-7895.
12. Li, G.; Qu, M.; Wan, J.; You, J. Antihypertensive effect of rice protein hydrolysate with in vivo angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac. J. Clin. Nutr. 2007, 16 (Suppl. 1), 275-280.
13. FitzGerald, R. J.; Meisel, H. Milk protein-derived peptide inhibitors of angiotesin-I-converting enzyme. Br. J. Nutr. 2000, 84, S33-S37.
14. Murray, B. A.; FitzGerald, R. J. Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des. 2007, 13, 773-791.
15. (15) Kumada, Y.; Hashimoto, N.; Hasan, F.; Terashima, M.; Nakanishi, K.; Jungbauer, A.; Katoh, S. Screening of ACE-inhibitory peptides from a random peptide-displayed phage library using ACE-coupled liposomes. J. Biotechnol. 2007, 131, 144-149. (Pubitemid 47187506)
16. Pripp, A. H.; Isaksson, T.; Stepaniak, L.; Sorhaug, T. Quantitative structure activity relationship modeling of ACE-inhibitory peptides derived from milk proteins. Eur. Food Res. Technol. 2004, 219, 579-583.
17. Vermeirssen, V.; Van Camp, J.; Verstraete, W. Bioavailability of angiotensin I converting enzyme inhibitory peptides. Br. J. Nutr. 2004, 92, 357-366.