In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation

British Journal of Clinical Pharmacology

Volumn 68, Issue 4, 2009, Pages 574-579

  Chetty, Manoranjenni ^a   D'Esposito, Fabrizio ^a   Zhang, Wei V ^a   Glen, John ^b   Dore, Glenys ^c   Stankovic, Zvijezdana ^b   Edwards, Robert J ^d   Ramzan, Iqbal ^a   Murray, Michael ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Macquarie Hospital   (United States)

^c ROYAL NORTH SHORE HOSPITAL   (Australia)

^d HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Clozapine; Cytochrome P450; Drug interaction; Risperidone

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; BENZATROPINE; CITALOPRAM; CLOZAPINE; CYTOCHROME C OXIDASE; CYTOCHROME P450 1A2; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; ETHINYLESTRADIOL PLUS LEVONORGESTREL; FINASTERIDE; FLUINDOSTATIN; FLUVOXAMINE; KETOCONAZOLE; LITHIUM CARBONATE; METFORMIN; PAROXETINE; QUETIAPINE; RANITIDINE; RISPERIDONE; SALBUTAMOL; SERTRALINE; TRIHEXYPHENIDYL; VALPROIC ACID; VENLAFAXINE;

ADULT; ARTICLE; BIOTRANSFORMATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ELIMINATION; DRUG OXIDATION; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA;

ADULT; ANTIPSYCHOTIC AGENTS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOZAPINE; CYTOCHROME P-450 ENZYME SYSTEM; DRUG COMBINATIONS; DRUG INTERACTIONS; FEMALE; FLUVOXAMINE; HUMANS; KETOCONAZOLE; MALE; MICROSOMES, LIVER; MIDDLE AGED; RISPERIDONE; SCHIZOPHRENIA; YOUNG ADULT;

EID: 70449084956     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2009.03476.x     Document Type: Article

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