The influence of parathyroid hormone-related protein (PTHrP) on tooth-germ development and osteoclastogenesis in alveolar bone of PTHrP-knock out and wild-type mice in vitro

Archives of Oral Biology

Volumn 47, Issue 9, 2002, Pages 665-672

  Mekaapiruk, Kongkwan ^a   Suda, Naoto ^a   Hammond, Vicki E ^b   Beck, Felix ^b   Kuroda, Takayuki ^a   Takano, Yoshiro ^a   Terashima, Tatsuo ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Alveolar bone; Gene deficient mouse; Organ culture; Osteoclasts; PTHrP; Tooth germ

Indexed keywords

ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ISOENZYME; PARATHYROID HORMONE RELATED PROTEIN; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE HORMONE; TARTRATE-RESISTANT ACID PHOSPHATASE;

ALVEOLAR BONE; ANIMAL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DIVISION; CONTROLLED STUDY; CYTOLOGY; DENTIN; DEVELOPMENTAL STAGE; EMBRYO; EMBRYOLOGY; EXPLANT; FEMALE; GENETICS; IN VITRO STUDY; JAW; KNOCKOUT MOUSE; MALE; MANDIBLE; MOLAR TOOTH; MOUSE; MOUSE MUTANT; MULTINUCLEAR CELL; NONHUMAN; ORGAN CULTURE; OSTEOCLAST; PHYSIOLOGY; PROTEIN FUNCTION; TOOTH DEVELOPMENT; TOOTH FLORA; TOOTH PAPILLA; WILD TYPE;

ACID PHOSPHATASE; ALVEOLAR PROCESS; ANIMALS; CELL DIVISION; FEMALE; ISOENZYMES; MALE; MICE; MICE, KNOCKOUT; ORGAN CULTURE TECHNIQUES; OSTEOCLASTS; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE HORMONES; TOOTH GERM;

EID: 0036744954     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9969(02)00026-2     Document Type: Article

References (23)

1. Amizuka, N., Henderson, J.E., Hoshi, K., Warshawsky, H., Ozawa, H., Goltzman, D., Karaplis, A.C., 1996. Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion. Endocrinology 137, 5055-5067.
2. Amling, M., Neff, L., Tanaka, S., Inoue, D., Kuida, K., Weir, E., Philbrick, W.M., Broadus, A.E., Baron, R., 1997. Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development. J. Cell Biol. 13, 205-213.
3. Beck, F., Tucci, J., Russell, A., Senior, P.V., Ferguson, M.W., 1995. The expression of the gene coding for parathyroid hormone-related protein (PTHrP) during tooth development in the rat. Cell Tissue Res. 280, 283-290.
4. Burtis, W.J., Brady, T.G., Orloff, J.J., Ersbak, J.B., Warrell Jr., R.P., Olson, B.R., Wu, T.L., Mitnick, M.E., Broadus, A.E., Stewart, A.F., 1990. Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N. Engl. J. Med. 322, 1106-1112.
5. Cole, A., Walters, L.M., 1987. Tartrate-resistant acid phosphatase in bone and cartilage following decalcification and cold-embedding in plastic. J. Histochem. Cytochem. 35, 203-206.
6. Karaplis, A.C., Luz, A., Glowachi, J., Bronson, R.T., Victor, L.J., Tybulewicz, V.L.Z., Kronenberg, H.M., Milligan, R.C., 1994. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes Dev. 8, 277-289.
7. Kitahara, Y., Suda, N., Kuroda, T., Beck, F., Hammond, V.E., Takano, Y., 2002. Disrupted tooth development in parathyroid hormone-related protein (PTHrP) gene-knockout mice. Bone 30, 48-56.
8. Lee, K., Deeds, J.D., Segre, G.V., 1995. Expression of parathyroid hormone-related peptide and its receptor messenger ribonucleic acids during fetal development of rats. Endocrinology 136, 453-463.
9. Liu, J.G., Tabata, M.J., Yamashita, K., Matsumura, T., Iwamoto, M., Kurisu, K., 1998. Developmental role of PTHrP in murine molars. Eur. J. Oral Sci. 106, 143-146.
10. Liu, J.G., Tabata, M.J., Fuiji, T., Ohmori, T., Abe, M., Ohsaki, Y., Kato, J., Wakisaka, S., Iwamoto, M., Kurisu, K., 2000. Parathyroid hormone-related protein is involved in protection against invasion of tooth germs by bone via promoting the differentiation of osteoclasts during tooth development. Mech. Dev. 95, 189-200.
11. Nakchbandi, I.A., Weir, E.E., Insogna, K.L., Philbrick, W.M., Broadus, A.E., 2000. Parathyroid hormone-related protein induces spontaneous osteoclast formation via a paracrine cascade. Proc. Natl. Acad. Sci. U.S.A. 97, 7296-7300.
12. Parfitt, A.M., Drezner, M.K., Glorieux, F.H., Kanis, J.A., Malluche, H., Meunier, P.J., Ott, S.M., Recker, R.R., 1987. Bone histomorphometry: standardization of nomenclature, symbols, and units. J. Bone Miner. Res. 2, 595-610.
13. Philbrick, W.M., Dreyer, B.E., Nakchbandi, I.A., Karaplis, A.C., 1998. Parathyroid hormone-related protein is required for tooth eruption. Proc. Natl. Acad. Sci. U.S.A. 95, 11846-11851.
14. Slavkin, H.C., Bringas Jr., P., Cummings, E., Grodin, M.S., 1982. Initiation of quail and mouse chondrogenesis and osteogenesis in serumless, chemically-defined medium. Calcif. Tissue Int. 34, 111-112.
15. Slavkin, H.C., Sasano, Y., Kikunaga, S., Bessem, C., Bringas Jr., P., Mayo, M., Luo, W., Mak, G., Rall, L., Snead, M.L., 1990. Cartilage, bone and tooth induction during early embryonic mouse mandibular morphogenesis using serumless, chemical-defined medium. Connect Tissue Res. 24, 41-51.
16. Suda, N., Shibata, S., Yamazaki, K., Kuroda, T., Senior, P.V., Beck, F., Hammond, V.E., 1999. Parathyroid hormone-related protein (PTHrP) regulates proliferation of condylar hypertrophic chondrocytes. J. Bone Miner. Res. 14, 1838-1847.
17. Suda, N., Baba, O., Udagawa, N., Terashima, T., Kitahara, Y., Takano, Y., Kuroda, T., Senior, PV., Beck, F., Hammond, V.E., 2001. Parathyroid hormone-related protein (PTHrP) is required for normal intramembranous bone development. J. Bone Miner. Res. 16, 2182-2191.
18. Thesleff, I., Partanen, A.M., Vasino, S., 1991. Epithelium-mesenchymal interactions in tooth morphogenesis: the roles of extracellular matrix, growth factors, and cell surface receptors. J. Craniofac. Genet. Dev. Biol. 11, 229-237.
19. Thomas, R.J., Guise, T.A., Yin, J.J., Elliott, J., Horwood, N.J., Martin, T.J., Gillespie, M.T., 1999. Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology 140, 4451-4458.
20. Tucci, J., Hammond, V.E., Senior, P.V., Gibson, A., Beck, F., 1996. The role of fetal parathyroid hormone-related protein in transplacental calcium transport. J. Mol. Endocrinol. 17, 159-164.
21. Wysolmerski, J.J., Broadus, A.E., Zhou, J., Fuchs, E., Milstone, L.M., Philbrick, W.M., 1994. Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development. Proc. Natl. Acad. Sci. U.S.A. 91, 1133-1137.
22. Wysolmerski, J.J., McCaughem-Carucii, J.F., Daifotis, A.G., Broadus, A.E., Philbrick, W.M., 1995. Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland. Development 121, 3539-3547.
23. Wysolmerski, J.J., Philbrick, W.M., Dunbar, M.E., Lanske, B., Kronenberg, H., Broadus, A.E., 1998. Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development 125, 1285-1294.