Improgan-like analgesics: A family of compounds derived from histamine antagonists

Medicinal Chemistry Research

Volumn 13, Issue 1-2, 2004, Pages 78-87

  Hough, L B ^a   Nalwalk, J W ^a   Menge, W ^b   Leurs, R ^b   Timmerman, H ^b  

^a ALBANY MEDICAL COLLEGE   (United States)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANTIHISTAMINIC AGENT; ANTINOCICEPTIVE AGENT; BURIMAMIDE; CIMETIDINE; FURAN DERIVATIVE; N [2 [(5 DIMETHYLAMINOMETHYLFURAN 2 YL)METHYLTHIO]ETHYL] N' METHYLTHIOUREA; N CYANO N' METHYL N'' [2 [(5 DIMETHYLAMINOMETHYLFURAN 2 YL)METHYLTHIO]ETHYL]GUANIDINE; UNCLASSIFIED DRUG; VUF 5401; VUF 8294;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG SYNTHESIS; MALE; NOCICEPTION; NONHUMAN; PAIN; RAT; TAIL FLICK TEST;

EID: 7044271353     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-004-0012-z     Document Type: Conference Paper

References (19)

1. Hough, L.B.; Nalwalk, J.W.; Barnes, W.G.; Warner, L.M.; Leurs, R.; Menge, W.M.P.B.; Timmerman, H.; Wentland, M., In: Glick, S.D.; Maisonneuve, I.M., ed.: New Medications for Drug Abuse. New York: New York Acad. Sci., 2000, pp. 25-40.
2. Li, B.Y.; Nalwalk, J.W.; Barker, L.A.; Cumming, P.; Parsons, M.E.; Hough, L.B., J. Pharmacol. Exp. Ther. 1996, 276:500-508.
3. Lamberti, C.; Bartolini, A.; Ghelardini, C; Malmberg-Aiello, P., Pharmacol. Biochem. Behav. 1996, 53:567-574.
4. Li, B.Y.; Nalwalk, J.W.; Finkel, J.M.; Glick, S.D.; Hough, L.B., Analgesia 1997, 3:15-20.
5. Bannoura, M.D.; Nalwalk, J.W.; Tang, Y.; Carlile, M.; Leurs, R.; Menge, W.M.P.B.; Timmerman, H.; Hough, L.B., Brain Res. 1998, 814:218-221.
6. Li, B.Y.; Nalwalk, J.W.; Hough, L.B., Brain Res. 1997, 748:168-174.
7. Hough, L.B., Mol. Pharmacol., 2001, 59:1-5.
8. Mobarakeh, J. I.; Nalwalk, J.W.; Watanabe, T.; Sakurada, S.; Hoffman, M.; Leurs, R.; Timmerman, H.; Silos-Santiago, I.; Yanai, K.; Hough, L. B., Brain Res. 2003, 974:146-152.
9. Hough, L.B.; Nalwalk, J.W.; Chen, Y.; Schuller, A.; Zhu, Y.; Zhang, J.; Menge, W.M.P.B.; Leurs, R.; Timmerman, H.; Pintar, J.E., Brain Res. 2000, 880:102-108.
10. Hough, L.B.; Nalwalk, J.W.; Barnes, W.G.; Leurs, R.; Menge, W.M.P.B.; Timmerman, H., Excerpta Medica International Congress Series 1224, Ed. T. Watanabe, H. Timmerman, K. Yanai, Elsevier, Amsterdam, 2001, pp. 237-242.
11. Svokos, K.; Nalwalk, J.W.; Leurs, R.; Menge, W.; Timmerman, H; Hough, L.B., Brain Research 2001, 923:12-19.
12. Hough, L.B.; Nalwalk, J.W.; Menge, H.W.; Leurs, R; Timmerman, H., Life Sci. 2001, 68:2751-2757.
13. Hough, L.B.; Nalwalk, J.W.; Stadel, R.; Timmerman, H.; Leurs, R.; Paria, B.C.; Wang, X.; Dey, S.K., J. Pharmacol. Exp. Ther. 2002, 303:314-322.
14. Sterk, G, H.; Timmerman, H., Eur. J. Med. Chem. 1987;22:427-432.
15. Price, B.J.; Clitherow, J.W.; Bradshaw, J., Arzneimittel 1977.
16. Crane, L.A.; Glick, S.D., Pharmacol. Biochem. Behav. 1979; 10:799-800.
17. Hough, L.B.; Nalwalk, J.W.; Li, B.Y.; Leurs, R.; Menge, W.M.P.B.; Timmerman, H.; Cioffi C.; Wentland, M., J. Pharmacol. Exp. Ther. 1997; 283:1534-1543.
18. Hough, L.B., Nalwalk J.W.; Leurs R.; Menge, W.M.P.B.; Timmerman H., Pharmacol. Biochem. Behav. 2000; 65:61-66.
19. Cooper, D.G.; Young, R.C.; Durant, G.J.; Ganellin, C.R. Comp. Med. Chem. 1990, 3:323-421.