A role for spinal, but not supraspinal, α2 adrenergic receptors in the actions of improgan, a powerful, non-opioid analgesic

Brain Research

Volumn 923, Issue 1-2, 2001, Pages 12-19

  Svokos, Konstantina ^a   Nalwalk, Julia W ^a   Leurs, Rob ^b   Menge, Wiro M P B ^b   Timmerman, Henk ^b   Hough, Lindsay B ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Alpha2 receptor; Analgesia; Cimetidine; Histamine; Improgan; Pain

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ANALGESIC AGENT; CLONIDINE; IMPROGAN; MORPHINE; UNCLASSIFIED DRUG; YOHIMBINE;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; HOT PLATE TEST; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TAIL FLICK TEST;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; ANIMALS; CIMETIDINE; CLONIDINE; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MALE; MORPHINE; NOCICEPTORS; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; SPINAL CORD; YOHIMBINE;

EID: 0035960876     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03191-2     Document Type: Article

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