BCG vaccine modulates intestinal and systemic response to β-lactoglobulin

Pediatric Allergy and Immunology

Volumn 15, Issue 5, 2004, Pages 408-414

  Rytkönen, Jani ^a   Karttunen, Tuomo J ^a   Karttunen, Riitta ^a   Valkonen, Kaija H ^a   Björkstén, Bengt ^b   Kokkonen, Jorma ^a,c  

^a UNIVERSITY OF OULU   (Finland)

^b LINKÖPING UNIVERSITY   (Sweden)

^c OULU UNIVERSITY HOSPITAL   (Finland)

Author keywords

lactoglobulin; Bacillus Calmette Gu rin; Gastrointestinal inflammation; Immunoglobulin E; Milk

Indexed keywords

BCG VACCINE; BETA LACTOGLOBULIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; INTERLEUKIN 4;

ANIMAL EXPERIMENT; ARTICLE; BCG VACCINATION; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DUODENUM; EOSINOPHIL; FOOD ALLERGY; GASTROINTESTINAL TRACT; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATORY CELL; INTESTINE MUCOSA; LAMINA PROPRIA; LYMPHOCYTIC INFILTRATION; MILK ALLERGY; NONHUMAN; PRIORITY JOURNAL; RAT; RISK REDUCTION; SENSITIZATION;

ANIMALS; BCG VACCINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERFERON TYPE II; INTERLEUKIN-4; INTESTINAL MUCOSA; LACTOGLOBULINS; MILK HYPERSENSITIVITY; RATS;

EID: 7044260297     PISSN: 09056157     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2004.00177.x     Document Type: Article

References (28)

1. SAARINEN KM, JUNTUNEN-BACKMAN K, JÄRVENPÄÄ AL, et al. Supplementary feeding in maternity hospitals and the risk of cow's milk allergy: a prospective study of 6209 infants. J Allergy Clin Immunol 1999; 104: 457-61.
2. WAL JM. Cow's milk allergens. Allergy 1998; 53: 1013-22.
3. SAMPSON HA, ANDERSON JA. Summary and recommendations: classification of gastrointestinal manifestations due to immunologic reactions to foods in infants and young children. J Pediatr Gastroenterol Nutr 2000; 30 (Suppl.): 87-94.
4. KOKKONEN J, RUUSKA T, KARTTUNEN TJ, NIINIMÄKI A. Mucosal pathology of the foregut associated with food allergy and recurrent abdominal pains in children. Acta Paediatr 2001; 90: 16-21.
5. ADKINS B. Development of neonatal Th1/Th2 function. Int Rev Immunol 2000; 19: 157-71.
6. MARCHANT A, GOETGHEBUER T, OTA MO, et al. Newborns develop a Th1-type immune response to Mycobacteruium bovis bacillus Calmette-Guérin vaccination. J Immunol 1999; 163: 2249-55.
7. KOH YI, CHOI IS, KIM WY. BCG infection in allergen-presensitized rats suppresses Th2 immune response and prevents the development of allergic asthmatic reaction. J Clin Immunol 2001; 21: 51-9.
8. YANG X, WANG S, FAN Y, ZHU L. Systemic mycobacterial infection inhibits antigen-specific immunoglobulin E production, bronchial mucus production and eosinophilic inflammation induced by allergen. Immunology 1999; 98: 329-37.
9. MARKS GB, NG K, ZHOU J, et al. The effect of neonatal BCG vaccination on atopy and asthma at age 7 to 14 years: an historical cohort study in a community with a very low prevalence of tuberculosis infection and a high prevalence of atopic disease. J Allergy Clin Immunol 2003; 111: 541-9.
10. GRÜBER C, MEINLSCHMIDT G, BERGMANN R, WAHN U, STARK K. Is early BCG vaccination associated with less atopic disease? An epidemiological study in German preschool children with different ethnic backgrounds. Pediatr Allergy Immunol 2002; 13: 177-81.
11. KRISHNA MT, SALVI SS. Could administration of bacille Calmette-Guérin vaccination at birth protect from the development of asthma and allergic diseases in the western world? Has this question been adequately investigated? Pediatr Allergy Immunol 2002; 13: 172-6.
12. RYTKÖNEN J, KARTTUNEN TJ, KARTTUNEN R, et al. Effect of heat denaturation on beta-lactoglobulin-induced gastrointestinal sensitization in rats: denatured βLG induces a more intensive local immunologic response than native βLG. Pediatr Allergy Immunol 2002; 13: 269-77.
13. VALKONEN KH, MARTTINEN N, ALATOSSAVA T. Preparative separation and characterization of beta-lactoglobulin genetic variants A and B from bovine milk. Milchwissenschaft 2000; 55: 126-9.
14. ERB KJ, HOLLOWAY JW, SOBECK A, MOLL H, LE GROS G. Infection of mice with Mycobacterium bovis-bacillus Calmette-Guérin (BCG) suppresses allergen-induced airway eosinophilia. J Exp Med 1998; 187: 561-9.
15. HYLKEMA MN, TIMENS W, LUINGE M, VAN DER WERF N, HOEKSTRA MO. The effect of bacillus Calmette-Guérin immunization depends on the genetic predisposition to Th2-type responsiveness. Am J Respir Cell Mol Biol 2002; 27: 244-9.
16. STEVENS TL, BOSSIE A, SANDERS VM, et al. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature 1988; 334: 255-8.
17. LAGRANDERIE M, BALAZUC AM, ABOLHASSANI M, et al. Development of mixed Th1/Th2 type immune response and protection against Mycobacterium tuberculosis after rectal or subcutaneous immunization of newborn and adult mice with Mycobacterium bovis BCG. Scand J Immunol 2002; 55: 293-303.
18. POWER CA, WEI G, BRETSCHER PA. Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous, subcutaneous, or intradermal route. Infect Immun 1998; 66: 5743-50.
19. KOKKONEN J, RUUSKA T, KARTFUNEN TJ, MAKI M. Lymphonodular hyperplasia of the terminal ileum associated with colitis shows an increase gammadelta + t-cell density in children. Am J Gastroenterol 2002; 97: 667-72.
20. NOWAK-WEGRZYN A, SAMPSON HA, WOOD RA, SICHERER SH. Food protein-induced enterocolitis syndrome caused by solid food proteins. Pediatrics 2003; 111: 829-35.
21. AUGUSTIN M, KARTTUNEN TJ, KOKKONEN J. TIA1 and mast cell tryptase in food allergy of children: increase of intraepithelial lymphocytes expressing TIA1 associates with allergy. J Pediatr Gastroenterol Nutr 2001; 32: 11-8.
22. DOHI T, FUJIHASHI K, KOGA T, et al. T helper type-2 cells induce ileal villus atrophy, goblet cell metaplasia, and wasting disease in T cell-deficient mice. Gastroenterology 2003; 124: 672-82.
23. TOZAWA K, HANAI H, SUGIMOTO K, et al. Evidence for the critical role of interleukin-12 but not interferon-gamma in the pathogenesis of experimental colitis in mice. J Gastroenterol Hepatol 2003; 18: 578-87.
24. SCHMIDT C, MARTH T, WITTIG BM, HOMBACH A, ABKEN H, STALLMACH A. Interleukin-12 antagonists as new therapeutic agents in inflammatory bowel disease. Pathobiology 2002; 70: 177-83.
25. RYAN M, MURPHY G, GOTHEFORS L, NILSSON J, STORSAETER J, MILLS KH. Bordetella pertussis respiratory infection in children is associated with preferential activation of type 1 T helper cells. J Infect Dis 1997; 175: 1246-50.
26. AUSIELLO CM, URBANI F, LA SALA A, LANDE R, CASSONE A. Vaccine- and antigen-dependent type 1 and type 2 cytokine induction after primary vaccination of infants with whole-cell or acellular pertussis vaccines. Infect Immun 1997; 65: 2168-74.
27. FREIER S, ERAN M, GOLDSTEIN R. The effect of immediate-type gastrointestinal allergic reactions on brush border enzymes and gut morphology in the rat. Pediatr Res 1985; 19: 456-9.
28. YAZDANBAKHSH M, KREMSNER PG, van REE R. Allergy, parasites, and the hygiene hypothesis. Science 2002; 296: 490-4.