Differential patterns of insulin-like growth factor-I and -II mRNA expression in medulloblastoma

Neuropathology and Applied Neurobiology

Volumn 30, Issue 5, 2004, Pages 503-512

  Van Doorn, J ^a   Gilhuis, H J ^b   Koster, J G ^a   Wesseling, P ^b   Reddingius, R E ^c   Gresnigt, M G ^a   Bloemen, R J ^a   Van Muijen, G N P ^b   Van Buul Offers, S C ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Cerebellum; IGF I; IGF II; Ki M1P; Medulloblastoma; Microglia

Indexed keywords

COMPLEMENTARY RNA; DIGOXIGENIN; MESSENGER RNA; SOMATOMEDIN B; SOMATOMEDIN C;

ADOLESCENT; ADULT; ARTICLE; CELL STRUCTURE; CELL SUBPOPULATION; CHILD; FEMALE; GENE EXPRESSION; GENE INDUCTION; GRAY MATTER; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MACROPHAGE; MALE; MALIGNANT NEOPLASTIC DISEASE; MEDULLOBLASTOMA; MICROGLIA; MITOGENESIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RNA PROBE; TUMOR CELL; TUMOR GROWTH; WHITE MATTER;

ADULT; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFANT; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MALE; MEDULLOBLASTOMA; MICROGLIA; RNA, MESSENGER;

EID: 7044237590     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2990.2004.00571.x     Document Type: Article

References (35)

1. Kleihues P, Cavenee WK. Pathology and Genetics of Tumours of the Nervous System (WHO). Lyon, France: IARC Press, 2000
2. Provias JP, Becker LE. Cellular and molecular pathology of medulloblastoma. J Neurooncol 1996; 29: 35-43
3. Goussia AC, Kyritsis AP, Agnantis NJ, Fuller GN. Cytogenetic and molecular genetic abnormalities in primitive neuroectodermal tumors of the central nervous system. Anticancer Res 2000; 20: 65-73
4. Click RP, Lichtor T, Unterman TG. Insulin-like growth factors in central nervous system tumors. J Neurooncol 1997; 35: 315-25
5. Reiss K. Insulin-like growth factor-I receptor - a potential therapeutic target in medulloblastomas. Expert Opin Ther Targets 2002; 6: 539-44
6. Patti R, Reddy CD, Geoerger B, Grotzer MA, Raghunath M, Sutton LN, Phillips PC. Autocrine secreted insulin-like growth factor-I stimulates MAP kinase-dependent mitogenic effects in human primitive neuroectodermal tumor/medulloblastoma. Int J Oncol 2000; 16: 577-84
7. Wang JY, Del Valle L, Gordon J, Rubini M, Romano G, Croul S, Peruzzi F, Khalili K, Reiss K. Activation of the IGF-IR system contributes to malignant growth of human and mouse medulloblastomas. Oncogene 2001; 20: 3857-68
8. Del Valle L, Enam S, Lassak A, Wang JY, Croul S, Khalili K, Reiss K. Insulin-like growth factor I receptor activity in human medulloblastomas. Clin Cancer Res 2002; 8: 1822-30
9. Zumkeller W, Westphal M. The IGF/IGFBP system in CNS malignancy. J Clin Pathol Clin Mol Pathol 2001; 54: 227-9
10. Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 1995; 16: 3-34
11. O'Dell SD, Day INM. Molecules in focus - insulin-like growth factor II (IGF-II). Int J Biochem Cell Biol 1998; 30: 767-71
12. Albrecht S, Waha A, Koch A, Kraus JA, Goodyer CG, Pietsch T. Variable imprinting of H19 and IGF2 in fetal cerebellum and medulloblastoma. J Neuropathol Exp Neurol 1996; 55: 1270-6
13. Simmen FA, Badinga L, Green ML, Kwak I, Song S, Simmen RC. The porcine insulin-like growth factor system: at the interface of nutrition, growth and reproduction. J Nutr 1998; 128: 315S-20S
14. Peeters-Scholte C, Koster J, van den Tweel E, Blomgren K, Hamers N, Zhu C, van Buul-Offers S, Hagberg H, van Bel F, Heijnen C, Groenendaal F. Effects of selective nitric oxide synthase inhibition on IGF-1, caspases and cytokines in a newborn piglet model of perinatal hypoxia-ischaemia. Dev Neurosci 2002; 24: 396-404
15. Melton D, Krieg P, Rebagliati M, Maniatis T, Zinn K, Green MR. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promotor. Nucleic Acids Res 1984; 12: 7035-56
16. Jansen M, Van Schaik FMA, Ricker AT, Bullock B, Woods DE, Gabbay KH, Nussbaum AL, Sussenbach JS, Van den Brande JL. Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature 1983; 306: 609-11
17. Jansen M, Van Schaik FMA, Van Tol H, Van den Brande JL, Sussenbach JS. Nucleotide sequences of cDNAs encoding precursors of human insulin-like growth factor II (IGF-II) and an IGF-II variant. FEBS Lett 1985; 179: 243-6
18. Tamimi Y, van der Poel HG, Denyn MM, Umbas R. Karthaus HF, DeBruyne FM, Schalken JA. Increased expression of high mobility group protein I (Y) in high grade prostatic cancer determined by in situ hybridization. Cancer Res 1993; 53: 5512-16
19. Smink JJ, Koster JG, Hendriks-Stegeman BI, Buul-Offers SC. Insulin-like growth factor (IGF) II induced changes in expression of IGF binding proteins in lymphoid tissues of hIGF-II transgenic mice. Endocrinology 1999; 140: 5876-82
20. Paulus W, Roggendorf W, Kirchner T. Ki-M1P as a marker for microglia and brain macrophages in routinely processed human tissues. Acta Neuropathol (Berl) 1992; 84: 538-44
21. Roggendorf W, Strupp S, Paulus W. Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol (Berl) 1996; 92: 288-93
22. Brown HG, Kepner JL, Perlman EJ, Friedman HS, Strother DR, Duffner PK, Kun LE, Goldthwaite PT, Burger PC. 'Large cell/anaplastic' medulloblastomas: a pediatric oncology group study. J Neuropathol Exp Neurol 2000; 59: 857-65
23. Eberhart CG, Kaufman WE, Tihan T, Burger PC. Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules. J Neuropathol Exp Neurol 2001; 60: 462-9
24. Scheepens A, Williams CE, Breier BH, Guan J, Gluckman PD. A role for the somatotropic axis in neural development, injury and disease. J Ped Endocrinol Metabol 2000; 13: 1483-91
25. O'Donnell SL, Frederick TJ, Krady JK, Vannucci SJ, Wood TL. IGF-I and microglia/macrophage proliferation in the ischemic mouse brain. Glia 2002; 39: 85-97
26. Aguado F, Sanchez-Franco F, Rodrigo J, Cacicedo L, Martinez-Murillo R. Insulin-like growth factor I-immunoreactive peptide in adult human cerebellar Purkinje cells: co-localization with low-affinity nerve growth factor receptor. Neuroscience 1994; 59: 641-50
27. McKelvie PA, Rosen KM, Kinney HC, Villa-Komaroff L. Insulin-like growth factor II expression in the developing human brain. J Neuropathol Exp Neurol 1992; 51; 464-71
28. Zhan S, Van Zhang LM, Young C, Helman LJ. Biallelic expression of all four IGF-II promoters and its association with increased methylation of H19 gene in human brain. Brain Res 1998; 792: 283-90
29. Zahn S, Shapiro DN, Helman LJ. Loss of imprinting in Ewing's sarcoma. Oncogene 1995; 11: 2503-7
30. Ogino S, Kubo S, Abdul-Karim FW, Cohen ML. Comparative immunohistochemical study of insulin-like growth factor II and insulin-like growth factor receptor type 1 in pediatric brain tumour. Ped Dev Pathol 2001; 4: 23-31
31. Nicholas RS, Stevens S, Wing MG, Compston DA. Microglia-derived IGF-II prevents TNF-alpha induced death of mature oligodendrocytes in vitro. J Neuroimmunol 2002; 124: 36-44
32. Beilharz EJ, Bassett NS, Sirimanne ES, Williams CE, Gluckman PD. Insulin-like growth factor II is induced during wound repair following hypoxic-ischemic injury in the developing rat brain. Mol Brain Res 1995: 29: 81-91
33. Ling EA, Wong WC. The origin and nature of ramified and amoeboid microglia: a historical review and current concepts. Glia 1993; 7: 9-18
34. Streit WJ, Kincaid-Colton CA. The brain's immune system. Sci Am 1995; 273: 38-43
35. Nicholas RS, Wing MG, Compston DAS. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. Eur J Neurosci 2001; 13: 959-67