Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-κB

European Journal of Neuroscience

Volumn 13, Issue 5, 2001, Pages 959-967

  Nicholas, Richard S T J ^a   Wing, Mark G ^a   Compston, Alastair ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Institute of Public Health   (United Kingdom)

Author keywords

In vitro; Oligodendrocyte precursor; Platelet derived growth factor; Rat

Indexed keywords

ANTIBODY; GALACTOSYLCERAMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; THROMBOCYTE GROWTH FACTOR ANTIBODY; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; IN VITRO STUDY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; ANTIBODIES; ANTISENSE ELEMENTS (GENETICS); APOPTOSIS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CULTURE MEDIA, CONDITIONED; I-KAPPA B PROTEINS; INTERFERON TYPE II; MALE; MICROGLIA; NF-KAPPA B; OLIGODENDROGLIA; PLATELET-DERIVED GROWTH FACTOR; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; STEM CELLS;

EID: 0035098870     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01470.x     Document Type: Article

References (49)

1. NF-κB: Ten years after
2. Apoptosis: Activate NF-κB or die?
3. The NF-κB and IκB proteins
4. 2+ accumulation
5. Cell death and control of cell survival in the oligodendrocyte lineage
6. Multiple extracellular signals are required for long-term oligodendrocyte survival
7. Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia
8. Hydrogen peroxide mediates amyloid beta protein toxicity
9. Expression of insulin-like growth factor-1 and IGF-binding protein 2 in the hippocampus following cytotoxic lesion of the dentate gyrus
10. GGF/Neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors
11. Selective activation of NF-B by nerve growth factor through the neurotrophin receptor p75
12. Monoclonal antibodies to a plasma antigen of neurons
13. Brain microglia/macrophages express neurotrophins that selectively regulate proliferation and function
14. A20 inhibits NF-kappaB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis
15. PI3K: Downstream AKTion blocks apoptosis
16. On the cellular source and function of interleukin-6 produced in the central nervous system in viral diseases
17. Enhanced synthesis of platelet-derived growth factor following injury induced by 6-hydroxydopamine in rat brain
18. Growth of cultured microglia
19. Astroglial control of oligodendrocyte survival mediated by PDGF and Leukemia Inhibitory Factor-like protein
20. Autocrine activation by interferon T of STAT factors following T cell activation
21. Interleukin-1 is an astroglial growth factor in the developing brain
22. Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication
23. Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation
24. PDGF and intracellular signaling in the timing of oligodendrocyte differentiation
25. Transcriptional regulation by extracellular signals: Mechanisms and specificity
26. Differences in angiogenic potential of classically vs alternatively activated macrophages
27. Microglia a sensor for pathological events in the CNS
28. p75 Neurotrophin receptor expression on adult human oligodendrocytes: Signalling without cell death in response to NGF
29. Nerve growth factor-dependent activation of NF-κB contributes to survival of sympathetic neurons
30. Lipopolysaccharide-stimulated rat brain macrophages release NGF in vitro
31. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
32. FGF modulates the PDGF-driven pathway of oligodendrocyte development
33. Microglial cell cytoxicity of oligodendrocytes is mediated through nitric oxide
34. PDGF promotes division and motility and inhibits premature differentiation of the oligodendrocyte-type-2 astrocyte progenitor cell
35. Expression of basic fibroblast growth factor and its receptor in human foetal microglia cells
36. Development of oligodendrocytes and schwann cells studied with a monoclonal antibody against galactocerebroside
37. A role for platelet-derived growth factor in normal gliogenesis in the central nervous system
38. Origins and early development of oligodendrocytes
39. NF-κB is a target of Akt in antiapoptotic PDGF signalling
40. Multiple nuclear factors interact with the immunoglobulin enhancer sequences
41. Inhibition of nuclear factor B (NFB) activity induces nerve growth factor-resistant apoptosis in PC12 cells
42. Sequence of rat RL/IF-1 encoding IκB-B-like activity and comparison with related proteins containing notch-like repeats
43. Expression of interferon T receptors on murine oligodendrocytes and its regulation by cytokines and mitogens
44. Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival
45. Autocrine regulation of macrophage differentiation and 92-kDa gelatinase production by tumor necrosis factor-alpha via alpha5 beta1 integrin in HL-60 cells
46. Competitive signalling between TrkA and p75 nerve growth factor receptors determines cell survival
47. SHP-1 associates with both platelet-derived growth factor receptor and the p85 subunit of phosphatidylinositol 3-kinase
48. Interactions between oligodendrocytes and microglia