Effect of oxyphenamone on sodium and calcium channels of guinea pig myocardial cells

Yaoxue Xuebao

Volumn 39, Issue 6, 2004, Pages 410-414

  Fan, Li Li ^a   Song, Zhen ^a   Wang, Tian You ^b  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Calcium channel; Oxyphenamone; Patch clamp; Positive inotropic effect; Sodium channel

Indexed keywords

ANTIARRHYTHMIC AGENT; OXYPHENAMONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM CURRENT; DRUG EFFECT; DRUG MECHANISM; GUINEA PIG; HEART MUSCLE CELL; INOTROPISM; NONHUMAN; PATCH CLAMP; SODIUM CHANNEL; SODIUM CURRENT;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CALCIUM CHANNELS, L-TYPE; CARDIOTONIC AGENTS; FEMALE; GUINEA PIGS; HEART VENTRICLES; MALE; MYOCYTES, CARDIAC; ORGANIC CHEMICALS; PATCH-CLAMP TECHNIQUES; SODIUM CHANNELS;

EID: 7044235391     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Fan LL, Sun LH, Lin Y. Effect of oxyphenamone, a new inodilator, on isolated cardiac muscles and arteries [J]. Acta Pharm Sin, 1997,32(11):808-812.
2. Fan LL, Sun LH, Li J. Effect of oxyphenamone, a new inodilator, on cardiac hemodynamics in normal rat, cat and dog [J]. Acta Pharm Sin, 1997,32(10):744-749.
3. Fan LL, Sun LH, Sun ZQ, et al. Therapeutic effect of a novel inodilator oxyphenamone on experimental heart failure induced by sodium pentobarbital [J]. Acta Pharm Sin, 1999,34(2):103-108.
4. Ye YX, Fan LL, Lin Y, et al. Biochemical mechanism of the positive inotropic effect of oxyphenamone [J]. Acta Pharm Sin, 1999,34(2):90-94.
5. 2+ affinity of cardiac troponin C [J]. Acta Pharm Sin, 1999,34(9):658-661.
6. 2+-tolerant myocytes for biochemical experiments from guinea-pig heart [J]. Life Sci, 1989,44(17):1231-1237.
7. 2+-sensitizers for the treatment of heart failure [J]. Curr Opin Crit Care, 2003,9(5):337-344.
8. 2+ current and developed tension in guinea-pig ventricular myocytes and papillary muscle: comparison with IBMX, milrinone and cilostazol [J]. Cardiovas Drugs Ther, 1999,13(2):105-113.
9. 2+ sensitizer, on ventricular arrhythmias and membrane ionic currents [J]. Eur J Pharmacol, 1996,298(3):247-256.
10. Mc Donald TF, Pelzer S, Trautwein W, et al. Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells [J]. Physiol Rev, 1994,74(2):365-507.