Biochemcal mechanism of the positive inotropic effect of oxyphenamone

Yaoxue Xuebao

Volumn 34, Issue 2, 1999, Pages 90-94

  Ye, Yixin ^a   Fan, Lili ^b   Lin, Yong ^b   Yang, Xiaoran ^a   Qiao, Xiaoying ^a   Chen, Lanlan ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Ca2+, Mg2+ ATPase; Calcium sensitizers; cAMP; Na+, K+ ATPase; Oxyphenamone; Phosphodiesterase

Indexed keywords

EID: 0041728364     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Bonting SL, Simon KA, Hawkins NM. Studies on sodium-potassium-activated adenosine triphosphatase. 1. Quantitative distribution of several tissues of the cat. Arch Biochem Biophys, 1961, 95:416
2. 2+. Life Sci, 1986, 39:1
3. Jones LR, Besch HR, Jr, Freming JW, et al. Separation of vesicles of cardiac sarcolemma from vesicles of cardiac sarcoplasmic reticulum comparative biochemical analysis of component activities. J Biol Chem, 1979, 254:530
4. 2+ sensitivity of myofibrillar Mg-adenosine triphophatase isolated from normal human and canine hearts. J Phrmacol Exp Ther, 1988, 246:30
5. Pagani ED, Solaro RJ. Methods for measuring functional properties of sarcoplasmic reticulum and myofibrils in small samples of myocardium. In: Schwartz A, ed. Methods in Pharmacology. Vol 5. New York: Plenum Publishing Corp, 1984, 49-61
6. Schoiz H, Meyer W. Phosphodiesterase inhibiting properties of newer inotropic agents. Circulation, 1986, 73(Suppl III):111
7. Ahn HS, Eardey D, Watkins R, et al. Effects of several newer cardiotonic drugs on cardiac cyclic AMP metabolism. Biochem Pharmacol, 1986, 35:1113
8. 2+ binding and ATPase activity of dog cardiac myofibrils by AL-L15BS, a novel cardiotonic agent. Circ Res, 1982, 51:290
9. 2+ binding by MCI-154, a novel cardiotonic agent. J Pharmacol Exp Ther, 1987, 250:272