Superoxide dismutase mimetic M40401 reduces ischemia-reperfusion injury and graft coronary, artery disease in rodent cardiac allografts

Transplantation

Volumn 78, Issue 8, 2004, Pages 1166-1171

  Murata, Seiichiro ^a   Miniati, Douglas N ^a   Kown, Murray H ^a   Koransky, Mark L ^a   Lijkwan, Maarten A ^a   Balsam, Leora B ^a   Robbins, Robert C ^a,b  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Graft coronary artery disease; Ischemia reperfusion injury; Superoxide dismutase

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; M 40401; MESSENGER RNA; MYELOPEROXIDASE; SCAVENGER; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; GRAFT CORONARY ARTERY DISEASE; HEART GRAFT; HEART PROTECTION; HETEROTOPIC TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; ISCHEMIA; ISCHEMIC HEART DISEASE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CARDIOTONIC AGENTS; CORONARY DISEASE; HEART TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-KAPPA B; ORGANOMETALLIC COMPOUNDS; RATS; RATS, INBRED ACI; RATS, INBRED STRAINS; SUPEROXIDE DISMUTASE; VASCULAR CELL ADHESION MOLECULE-1;

EID: 7044227571     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000137321.34200.FA     Document Type: Article

References (21)

1. Hertz MI, Mohacsi PJ, Taylor DO, et al. The registry of the International Society for Heart and Lung Transplantation: introduction to the Twentieth Annual Reports - 2003. J Heart Lung Transplant 2003; 22(6): 610.
2. Taylor DO, Edwards LB, Mohacsi PJ, et al. The registry of the International Society for Heart and Lung Transplantation: twentieth official adult heart transplant report - 2003. J Heart Lung Transplant 2003; 22(6): 616.
3. Trulock EP, Edwards LB, Taylor DO, et al. The Registry of the International Society for Heart and Lung Transplantation: Twentieth Official adult lung and heart-lung transplant report - 2003. J Heart Lung Transplant 2003; 22(6): 625.
4. Miniati DN, Lijkwan MA, Murata S, et al. Effects of adenoviral upregulation of bcl-2 on oxidative stress and graft coronary artery disease in rat heart transplants. Transplantation 2003; 76(2): 382.
5. Salvemini D, Wang ZQ, Zweier JL, et al. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science 1999; 286(5438): 304.
6. Cuzzocrea S, Mazzon E, Dugo L, et al. Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion. Br J Pharmacol 2001; 132(1): 19.
7. Salvemini D, Mazzon E, Dugo L, et al. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. Br J Pharmacol 2001; 132(4): 815.
8. Vela C, Cristol JP, Maggi MF, et al. Oxidative stress in renal transplant recipients with chronic rejection: rationale for antioxidant supplementation. Transplant Proc 31 (1-2):1310, 1999.
9. Cristol JP, Vela C, Maggi MF, et al. Oxidative stress and lipid abnormalities in renal transplant recipients with or without chronic rejection. Transplantation 1998; 65(10): 1322.
10. Land W, Schneeberger H, Schleibner S, et al. The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants. Transplantation 1994; 57(2): 211.
11. Ono K, Lindsey ES. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg 1969; 57(2): 225.
12. Mullane KM, Kraemer R, Smith B. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Methods 1985; 14(3): 157.
13. Poston RS Jr., Billingham ME, Pollard J, et al. Effects of increased ICAM-1 on reperfusion injury and chronic graft vascular disease. Ann Thorac Surg 1997; 64(4): 1004.
14. Murata S, Miniati DN, Kown MH, et al. Elevated cyclic adenosine monophosphate ameliorates ischemia-reperfusion injury in rat cardiac allografts. J Heart Lung Transplant 2003; 22(7): 802.
15. Poston RS, Billingham M, Hoyt EG, et al. Rapamycin reverses chronic graft vascular disease in a novel cardiac allograft model. Circulation 1999; 100(1): 67.
16. Behrendt D, Ganz P, Fang JC. Cardiac allograft vasculopathy. Curr Opin Cardiol 2000; 15(6): 422.
17. Jordan JE, Zhao ZQ, Vinten-Johansen J. The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res 1999; 43(4): 860.
18. Collins T. Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion. Lab Invest 1993; 68(5): 499.
19. Carden DL, Granger DN. Pathophysiology of ischaemia-reperfusion injury. J Pathol 2000; 190(3): 255.
20. Luscinskas FW, Gimbrone MA Jr. Endothelial-dependent mechanisms in chronic inflammatory leukocyte recruitment. Annu Rev Med 1996; 47: 413.
21. Feeley BT, Miniati DN, Park AK, et al. Nuclear factor-kappaB transcription factor decoy treatment inhibits graft coronary artery disease after cardiac transplantation in rodents. Transplantation 2000; 70(11): 1560.