-
1
-
-
35148826938
-
Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm
-
DOI 10.1016/j.ccr.2007.10.001, PII S153561080700270X
-
Soussi T, Wiman KG. Shaping genetic alterations in human cancer: The p53 mutation paradigm. Cancer Cell 2007;12:303-312. (Pubitemid 47539312)
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 303-312
-
-
Soussi, T.1
Wiman, K.G.2
-
2
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997;387:296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
3
-
-
47649096991
-
Structural biology of the tumor suppressor p53
-
Joerger AC, Fersht AR. Structural biology of the tumor suppressor p53. Annu Rev Biochem 2008;77:557-582.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 557-582
-
-
Joerger, A.C.1
Fersht, A.R.2
-
4
-
-
70350784064
-
P53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy
-
Schlette EJ, Admirand J, Wierda W, et al. p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy. Leuk Lymphoma 2009;50: 1597-1605.
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 1597-1605
-
-
Schlette, E.J.1
Admirand, J.2
Wierda, W.3
-
5
-
-
23044510136
-
Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia
-
DOI 10.1200/JCO.2005.12.051
-
Keating MJ, O'Brien S, Albitar M, et al. Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia. J Clin Oncol 2005;23:4079-4088. (Pubitemid 46211313)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.18
, pp. 4079-4088
-
-
Keating, M.J.1
O'Brien, S.2
Albitar, M.3
Lerner, S.4
Plunkett, W.5
Giles, F.6
Andreeff, M.7
Cortes, J.8
Faderl, S.9
Thomas, D.10
Koller, C.11
Wierda, W.12
Detry, M.A.13
Lynn, A.14
Kantarjian, H.15
-
6
-
-
58249117812
-
The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype
-
Dicker F, Herholz H, Schnittger S, et al. The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype. Leukemia 2009;23:117-124.
-
(2009)
Leukemia
, vol.23
, pp. 117-124
-
-
Dicker, F.1
Herholz, H.2
Schnittger, S.3
-
7
-
-
61549089361
-
The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: Implications for overall survival and chemorefractoriness
-
Rossi D, Cerri M, Deambrogi C, et al. The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: Implications for overall survival and chemorefractoriness. Clin Cancer Res 2009;15:995-1004.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 995-1004
-
-
Rossi, D.1
Cerri, M.2
Deambrogi, C.3
-
8
-
-
54049141334
-
Mono-allelic TP53 inactivation is associated with poor prognosis in CLL: Results from a detailed genetic characterization with long term followup
-
Zenz T, Krober A, Scherer K, et al. Mono-allelic TP53 inactivation is associated with poor prognosis in CLL: Results from a detailed genetic characterization with long term followup. Blood 2008;112:3322-3329.
-
(2008)
Blood
, vol.112
, pp. 3322-3329
-
-
Zenz, T.1
Krober, A.2
Scherer, K.3
-
9
-
-
0035437138
-
Stankovic T. p53 dysfunction in B-cell chronic lymphocytic leukemia: Inactivation of ATM as an alternative to TP53 mutation
-
Pettitt AR, Sherrington PD, Stewart G, Cawley JC, Taylor AM, Stankovic T. p53 dysfunction in B-cell chronic lymphocytic leukemia: Inactivation of ATM as an alternative to TP53 mutation. Blood 2001;98:814-822.
-
(2001)
Blood
, vol.98
, pp. 814-822
-
-
Pettitt, A.R.1
Sherrington, P.D.2
Stewart, G.3
Cawley, J.C.4
Taylor, A.M.5
-
10
-
-
70350745731
-
TP53 abnormalities in chronic lymphocytic leukemia exhibit a disease specific profile: Meta-analysis of 270 mutations
-
Zenz T, Smadova J, Vollmer D, et al. TP53 abnormalities in chronic lymphocytic leukemia exhibit a disease specific profile: Meta-analysis of 270 mutations. ASH Ann Meet Abstr 2008;112:2077.
-
(2008)
ASH Ann Meet Abstr
, vol.112
, pp. 2077
-
-
Zenz, T.1
Smadova, J.2
Vollmer, D.3
-
11
-
-
57849158643
-
How little is too much? p53 inactivation: From laboratory cutoff to biological basis of chemotherapy resistance
-
Zenz T, Habe S, Denzel T, Winkler D, Dohner H, Stilgenbauer S. How little is too much? p53 inactivation: From laboratory cutoff to biological basis of chemotherapy resistance. Leukemia 2008;22:2257-2258.
-
(2008)
Leukemia
, vol.22
, pp. 2257-2258
-
-
Zenz, T.1
Habe, S.2
Denzel, T.3
Winkler, D.4
Dohner, H.5
Stilgenbauer, S.6
-
12
-
-
33846219417
-
Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia
-
Byrd JC, Lin TS, Dalton JT, et al. Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia. Blood 2007;109:399-404.
-
(2007)
Blood
, vol.109
, pp. 399-404
-
-
Byrd, J.C.1
Lin, T.S.2
Dalton, J.T.3
-
13
-
-
33947243663
-
Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: Results of a phase II study
-
Chanan-Khan A, Miller KC, Musial L, et al. Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: Results of a phase II study. J Clin Oncol 2006;24:5343-5349.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5343-5349
-
-
Chanan-Khan, A.1
Miller, K.C.2
Musial, L.3
-
14
-
-
45949100928
-
Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
-
Ferrajoli A, Lee BN, Schlette EJ, et al. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood 2008;111:5291-5297.
-
(2008)
Blood
, vol.111
, pp. 5291-5297
-
-
Ferrajoli, A.1
Lee, B.N.2
Schlette, E.J.3
-
15
-
-
70350783410
-
Detailed analysis of p53 pathway defects in fludarabine-refractory CLL: Dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
-
Jul. [Epub ahead of print]
-
Zenz T, Habe S, Denzel T, et al. Detailed analysis of p53 pathway defects in fludarabine-refractory CLL: Dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial. Blood 2009 Jul 30. [Epub ahead of print].
-
(2009)
Blood
, pp. 30
-
-
Zenz, T.1
Habe, S.2
Denzel, T.3
|