Genetic polymorphism FecB and BMP15 genes and its association with litter size in sangsari sheep breed of Iran

Journal of Animal and Veterinary Advances

Volumn 8, Issue 5, 2009, Pages 1025-1031

  Kasiriyan, Mohammad Mehdi ^a   Hafezeyan, Hasan ^b   Sayahzadeh, Hadi ^b   Jamshidi, Reza ^c   Asghari, Saied Reza ^a   Irajeyan, Gholam Hossein ^a   Buesagh, Hamzeh ^a  

^a Damghan Rasool Akram University   (Iran)

^b UNIVERSITY OF MAZANDARAN   (Iran)

^c SEMNAN UNIVERSITY   (Iran)

Author keywords

BMP15; FecB; Genetic polymorphism; PCR; Polymorphism; Sangsari sheep

Indexed keywords

EID: 70350756003     PISSN: 16805593     EISSN: 1993601X     Source Type: Journal    
DOI: 10.3923/javaa.2009.1025.1031     Document Type: Article

References (43)

1. Baird, D.T. and B.K. Campbell, 1998. Follicle selection in sheep with breed differences in ovulation rate. Mol. Cell. Endocrinol., 145: 89-95.
2. Bodin, L., F. Lecerf, C. Pisselet, M. San Cristhal, M. Bibe and P. Mulsant, 2003. How many mutations are associated with increased ovulation rate and litter size in progeny of Lacaune meat sheep? In: Proc. Int. Workshop on Major Genes and QTL in Sheep and Goats. INRA, Toulouse, France, pp: 2-11.
3. Chu, M.X., Wang, S.C. Ye and L. Fang, 2004. Association between PCR-SSCP of growth differentiation factor 9 gene and high prolificacy in small tail han sheep. Anim. Biotechnol., 15: 111-120.
4. Chu, M.X., Z.H. Liu, C.L. Giao, Y.Q. He, L. Fang, S.C. Ye, G.H. Chen and G.Y. Wang, 2007. Mutations in BMPR-IB and BMP-15 genes are associated with litter size in Small Tailed Han sheep (Ovis aries). J. Anim. Sci., 85: 324-330.
5. Davis, G.H., J.C. McEwan, P.F. Fennessy, K.G. Dodds and P.A. Farquhar, 1991. Evidence for the presence of a gene influencing ovulation rate on the X chromosome of sheep. Biol. Reprod., 44: 620-624.
6. Davis, G.H., J.C. McEwan, P.F. Fennessy, K.G. Dodds, and K.P. McNatty 1992. Infertility due to bilateral ovarian hypoplasia in sheep homozygous (FecXI FecXI) for the Inverdale prolificacy gene located on the X chromosome. Biol. Reprod., 46: 636-640.
7. Davis, G.H., G.D. Bruce andK.G. Dodds, 2001. Ovulation rate and litter size of prolific Inverdale (FecXI) and Hanna (FecXH) sheep. Proc. Assoc. Advmt. Arum. Breed. Genet, 14: 175-178.
8. Davis, G.H., S.M. Galloway, IK. Ross, S.M. Gergan, J. Ward, B.V. Nimbkar, P.M. Ghalsasi, C. Nimbkar, G.D. Gray, I. Inounu, B. Tiesnamurti, J.P. Hanrahan and T. Wilson, 2002. DNA Tests in Prolific Sheep from 8 Countries Provide new evidence on origin of the Booroola (FecB) Mutation. Biol. Reprod., 66: 1869-1874.
9. Davis, G.H., 2005. Major genes affecting ovulation rate in sheep. Genet. Sel. Evol., 37 (Supple.1): S11-S23.
10. Davis, G.H., L. Balakrishnan, I.K. Ross, T. Wilson, M. Galloway, B.M. Lumsden, J.P. Hanrahan, M.X. Mullen, Z. Mao, G.L. Wang, Z.S. Zhao, J.J. Robinson, A.P. Mavrogenis, C. Papachristoforo, C. Peter, R. Baumung, P. Cardyn, I. Boujenane, N.E. Cockett, E. Eythorsdottir, J.J. Arranz and D.R. Notter, 2006. Investigation of the Booroola (FecB) and Inverdale (FecXI) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries. Anim. Reprod. Sci., 92: 7-96.
11. Dong, J.W., D.F. Albertini, K. Nishimori, T.R. Kumar, N. Lu and M.M. Matzuka, 1996. Growth differentation factor 9 is required during early ovarian folliculgenesis. Nature, 383 (66): 531-535.
12. Galloway, S.M., V. Hanrahan, K.G. Dodds, M.D. Potts, A.M. Crawford and D.F. Hill, 1996. A linkage map of the ovine X chromosome. Gen. Res., 6: 667-677.
13. Galloway, S.M., K.P. McNatty, L.M. Cambridge, M.P.E. Laitinen, J.L. Juengel, T.S. Jokiranta, R.J. McLaren, K. Luiro, K.G. Dodds, G.W. Montgomery, A.E. Beattie, G.H. Davis and O. Ritvos, 2000. Mutations in an oocyte-denved growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat. Gen., 25: 279-283.
14. Gootwine, E., 1986. Incereasing prolificacy of the fat tail Awassi sheep using the booroola FecB gene. Ciheam-options Mediterranees, pp: 79-87.
15. Guan, F., S.R. Liu, G.Q. Shi, IT. Ai, D.G. Mao and L.G. Yang, 2006. Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development. Acta Genetica Sinica, 33: 117-124.
16. Jia, C.L., N. Li, X.B. Zhao, X.P. Zhu and Z.H. Jia, 2005. Association of single nucleotide polymorphisms in exon 6 region of BMPRIB gene with litter size traits in sheep. Asian-Aust J. Anim. Sci., 18: 1375-1378.
17. Juengel, J.L., N.L. Hudson, L. Whiting and K.P. McNatty, 2004. Effects of immunization against bone morphogenetic protein 15 and growth differentiation factor 9 on pergnancy in Ewes. Biol. Reprod., 70:557-561.
18. Hanrahan, J.P., S.M. Gergan, P. Mulsant, M. Mullen, G.H. Davis, R. Powell and S.M. Galloway, 2004. Mutations in the genes for oocyte derived growth factors GDF 9 and BMP 15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare Sheep (Ovis aries). Biol. Reprod., 70: 900-909.
19. Hayashi, M., E.A. McGee, G. Mm, C. Klein, U.M. Rose, M. Van Duin and A.J. Hsueh, 1999. Recombinate Growth Differentiation Factor9 (GDF9) enhance growth and diferentation of cultured early ovarian follicule. Endocrinology, 140(3): 1236-1244.
20. Henderson, C.R., 1987. Simulation to examine distribution of estimators of variances and ratios of variances. J. Dairy Sci., 61: 267-273.
21. Hsueh, A.J., E.A. McGee, M. Hayashi and S.Y. Hsu, 2000. Hormonal regulation of early follicule development in the rate ovary. Mol. Cell. Endocnnol., 163 (1-2): 95-100.
22. Laitinen, M., K. Vuojolainen, R. Jaatinen, I. Ketola, J. Aaltonen, E. Lehtonen, M. Heikinheimo and O. Ritvos, 1998. Anovel Growth Differentiation Factor9 (GDF-9) related factor is co-expressed with GDF-9 in mouse oocytes during folliculogenesis. Mechanisms Dev., 78: 135-140.
23. Lanneluc, I., R.D. Drinkwater, J.M. Elsen, DJ. Hetzel, T.C. Nguyen, L.R. Piper, J. Thimonier, B. Harrison and J. Gellin, 1994. Genetic markers for the Booroola Fecundity (Fee) gene in sheep. Mamm. Genome, 5: 26-33.
24. Liao, W.X., R.K. Moore and S. Shimasaki, 2004. Functional and molecular characterization of naturally occurring mutations in the oocyte-secreted factors bone morphogenetic protein-15 and growth and differentiation factor-9. J. Biol. Chem., 17: 17391-17396.
25. Liu, S.F., Y.L. Jiang and L.X. Du, 2003. Studies of BMPR-IB and BMP 15 as candidate genes for fecundity in Little Tailed Han sheep. Acta Genetica Smica, 30: 755-760.
26. Miller, S.A., D.D. Dykes andH.F. Polesky, 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res., 16: 1215.
27. McPherone, A.C. and SJ. Lee, 1993. GDF-3 and GDF-92 new members of the transforming growth factor B superfamily contatining a novel pattern of cysteines. J. Biol. Chem., 268 (5): 344-449.
28. McGrath, S.A., A.F. Esquela and S.J. Lee, 1995. Oocyte-specific expression of growth differentiantion factor 9. Mol. Cell. Endocrinol. 9: 131-136.
29. McNatty, K.P., J.L. Jungel, K.L. Reader, S. Lun, S. Myllymaa, S.B. Lawrence, A. Western, M.F. Meerasahib, D.G. Mottershead, N.P. Groome, O.Ritvos and M.P. Laitinen, 2005. Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulose cell function in ruminants. Reproduction, 129: 481-487.
30. Montgomery, G.W., A.M. Crawford, J.M. Penty, K.G. Dodds, A.J. Ede, C.A. Pierson, E.A. Lord, S.M. Galloway and A.E. Schmack, 1993. The ovine Booroola Fecundity gene (FecB) is linked to markers from a region of human chromosome 4q. Nat Gen., 4 (4): 327-328.
31. Mulsant, P., F. Lecerf, S. Fabre, L. Schibler, P. Monget, I.Lanneluc, C. Pisselet, J. Riquet, D. Monniaux, I. Callebaut, E. Cribiu, J. Thimonier, J. Teyssier, L. Bodin, Y. Cogme, N. Chitour and J.M. Elsen, 2001. Mutation in bone morphogenetic protein receptor-IB is associatedwith increased ovulation rate in Booroola Merino ewes. Proc. Natl. Acad. Sci. USA, 98: 104-109.
32. Piper, L.R. and B.M. Bindon, 1982. The Booroola Merino and the Performance of Medium Non-peppin Crosses at Armidale. In: Piper, L.R., B.M. Bindon and R.D. Nethery (Eds.). The Booroola Merino. Melbourne: CSIRO, pp: 9-19.
33. Piper, L.R., B.M. Bindon and G.H. Davis, 1985. The Single Gene Inheritance of the High Litter Size of the Booroola Merino. In: Land, R.B. and D.W. Robinson, (Eds.). Genetics of Reproduction in Sheep. London: Butterworths, pp: 115-125.
34. Rohrer, G.A., 1999. Mapping four genes from human chromosome 4 to porcine chromosome 8 further develops the comparative map for an economically important chromosome of the swine genome. Anim. Gen., 30: 60-62.
35. Sadighi, M., G.W. Montgomery, K.J. Bodensteiner and S.M. Galloway, 1998. The growth differentiation factor 9 maps to sheep chromosome 5. Anim. Genetics, 29 (Suppl. 1): 36.
36. Souza, C.J.H., C. MacDougall, B.K. Cambell, A.S. McNeilly and D.T. Baird, 2001. The Booroola (FecB) phenotype is asspciated with a mutation in the Bone Morphogenetic Receptor type IB (BMPRIB) gene. J. Endocrinol., 169: R1-R6.
37. Vitt, U.A., E.A. McGee and A.J. Hayashi, 2000. In vivo treatment with GDF9 stimulates primordial and primery follicule progression and theca cell marker cypl7 in ovaries of immature rats. Endocrinology, 141 (10): 3814-3820.
38. Wang, G.L.,X.Z. Mao, G.H. Davis, Z.S. Zhao, L.J. Zhang and Y.Q. Zeng, 2003a. DNA tests in Hu sheep and Han sheep (smalltail) showed the existence of Booroola (FecB) mutation. J. Nanjing Agric. Univ., 26: 104-106.
39. Wang, Q.G., F.G. Zhong, H. Li, X.H. Wang, S.R. Liu and X.J. Chen, 2003b. The polymorphism of BMPR-IB gene associated with litter size in sheep. Grass-feeding Livest., 2: 20-23.
40. Wang, Q.G., F.G. Zhong, H. Li, X.H. Wang, S.R. Liu, X.J. Chen and S.Q. Gan, 2005. Detection on major gene on litter size in sheep. Hereditas (Beijing), 27: 80-84.
41. Wilkie, P.J., A.A. Paszek, C.W. Beattie, L.J. Alexander, M.B. Wheeler and L.B. Schook, 1999. A genomic scan of porcine reproductive traits reveals possible Quantitative Trait Loci (QTLs) for number of corpora lutea. Mammalian Genome, 10: 573-578.
42. Wilson, T., Yang, Wu., J.L. Juengel, I.K. Ross, J.M. Lumsden, E.A. Lord, K.G. Dodds, G.A. Walling, J.C. McEwan, A.R. O'Cornell, K.P. McNatty and G.W. Montgomery, 2001. Highly prolific Booroola sheep have a mutation in the Intracellular Kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells. Biol. Reprod., 64: 1225-1235.
43. Yan, Y.D., M.X. Chu, Y.Q. Zeng, L. Fang, S.C. Ye, L.M. Wang, Q.K. Guo, D.Q. Han, Z.X. Zhang, X.J. Wang and X.Z. Zhang, 2005. Study on bone morphogenetic protein receptor IB as a candidate gene for prolificacy in Small Tailed Han sheep and Hu sheep. J. Agric. Biotechnol., 13: 66-71.