메뉴 건너뛰기




Volumn 4, Issue 3, 2009, Pages 183-189

Recent advances in the development of immunoadhesins for immune therapy and as anti-infective agents

Author keywords

Anti infective agents; Fc fusion protein; Fc quimera; Immune therapy; Immunoadhesin; Immunoregulatory

Indexed keywords

ABATACEPT; AFLIBERCEPT; ALEFACEPT; ANTIINFECTIVE AGENT; ATACICEPT; BAMINERCEPT; BELATACEPT; BRIOBACEPT; CD4 IMMUNOGLOBULIN; ETANERCEPT; IMMUNOGLOBULIN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; RILONACEPT; UNCLASSIFIED DRUG;

EID: 70350749898     PISSN: 1574891X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157489109789318550     Document Type: Review
Times cited : (7)

References (49)
  • 1
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
    • Boucher HW, Talbot GH, Bradley JS, et al. Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 2009; 48(1): 1-12.
    • (2009) Clin Infect Dis , vol.48 , Issue.1 , pp. 1-12
    • Boucher, H.W.1    Talbot, G.H.2    Bradley, J.S.3
  • 2
    • 62749137214 scopus 로고    scopus 로고
    • Novel approaches to discovery of antibacterial agents
    • Taylor PL, Wright GD. Novel approaches to discovery of antibacterial agents. Anim Health Res Rev 2008; 9(2): 237-246.
    • (2008) Anim Health Res Rev , vol.9 , Issue.2 , pp. 237-246
    • Taylor, P.L.1    Wright, G.D.2
  • 3
    • 0031907818 scopus 로고    scopus 로고
    • Antibody-based therapies as anti-infective agents
    • Casadevall A. Antibody-based therapies as anti-infective agents. Expert Opin Investig Drugs 1998; 7(3): 307-321.
    • (1998) Expert Opin Investig Drugs , vol.7 , Issue.3 , pp. 307-321
    • Casadevall, A.1
  • 5
    • 0030932133 scopus 로고    scopus 로고
    • Immunoadhesins as research tools and therapeutic agents
    • Ashkenazi A, Chamow SM. Immunoadhesins as research tools and therapeutic agents. Curr Opin Immunol 1997; 9(2): 195-200.
    • (1997) Curr Opin Immunol , vol.9 , Issue.2 , pp. 195-200
    • Ashkenazi, A.1    Chamow, S.M.2
  • 6
    • 0030041799 scopus 로고    scopus 로고
    • Immunoadhesins: Principles and applications
    • Chamow SM, Ashkenazi A. Immunoadhesins: Principles and applications. Trends Biotechnol 1996; 14(2): 52-60.
    • (1996) Trends Biotechnol , vol.14 , Issue.2 , pp. 52-60
    • Chamow, S.M.1    Ashkenazi, A.2
  • 7
    • 34748865088 scopus 로고    scopus 로고
    • Antibody therapeutics: Isotype and glycoform selection
    • Jefferis R. Antibody therapeutics: Isotype and glycoform selection. Expert Opin Biol Ther 2007; 7(9): 1401-1413.
    • (2007) Expert Opin Biol Ther , vol.7 , Issue.9 , pp. 1401-1413
    • Jefferis, R.1
  • 8
    • 33646352962 scopus 로고    scopus 로고
    • Potent antibody therapeutics by design
    • Carter PJ. Potent antibody therapeutics by design. Nat Rev Immunol 2006; 6(5): 343-357.
    • (2006) Nat Rev Immunol , vol.6 , Issue.5 , pp. 343-357
    • Carter, P.J.1
  • 9
    • 0027944684 scopus 로고
    • Generation of soluble interleukin-1 receptor from an immunoadhesin by specific cleavage
    • Beck JT, Marsters SA, Harris RJ, Carter P, Ashkenazi A, Chamow SM. Generation of soluble interleukin-1 receptor from an immunoadhesin by specific cleavage. Mol Immunol 1994; 31(17): 1335-1344.
    • (1994) Mol Immunol , vol.31 , Issue.17 , pp. 1335-1344
    • Beck, J.T.1    Marsters, S.A.2    Harris, R.J.3    Carter, P.4    Ashkenazi, A.5    Chamow, S.M.6
  • 10
    • 67349098558 scopus 로고    scopus 로고
    • Human interleukin 10 receptor 1/IgG1-Fc fusion proteins: Immunoadhesins for human IL-10 with therapeutic potential
    • Terai M, Tamura Y, Otsuka E, Berd D, Mastrangelo MJ, Sato T. Human interleukin 10 receptor 1/IgG1-Fc fusion proteins: Immunoadhesins for human IL-10 with therapeutic potential. Cancer Immunol Immunother 2009; 58(8): 1307-1317.
    • (2009) Cancer Immunol Immunother , vol.58 , Issue.8 , pp. 1307-1317
    • Terai, M.1    Tamura, Y.2    Otsuka, E.3    Berd, D.4    Mastrangelo, M.J.5    Sato, T.6
  • 11
    • 0025611904 scopus 로고
    • Structural characterization of a recombinant CD4-IgG hybrid molecule
    • Harris RJ, Wagner KL, Spellman MW. Structural characterization of a recombinant CD4-IgG hybrid molecule. Eur J Biochem 1990; 194(2): 611-620.
    • (1990) Eur J Biochem , vol.194 , Issue.2 , pp. 611-620
    • Harris, R.J.1    Wagner, K.L.2    Spellman, M.W.3
  • 13
    • 0032810008 scopus 로고    scopus 로고
    • Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities
    • Armour KL, Clark MR, Hadley AG, Williamson LM. Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities. Eur J Immunol 1999; 29(8): 2613-2624.
    • (1999) Eur J Immunol , vol.29 , Issue.8 , pp. 2613-2624
    • Armour, K.L.1    Clark, M.R.2    Hadley, A.G.3    Williamson, L.M.4
  • 14
    • 0035794194 scopus 로고    scopus 로고
    • High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R
    • Shields RL, Angela KN, Kyu H, et al. High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J Biol Chem 2001; 276(9): 6591-6604.
    • (2001) J Biol Chem , vol.276 , Issue.9 , pp. 6591-6604
    • Shields, R.L.1    Angela, K.N.2    Kyu, H.3
  • 15
    • 0034655265 scopus 로고    scopus 로고
    • Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc
    • Idusogie EE, Presta LG, Gazzano-Santoro, et al. Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc. J Immunol 2000; 164(8): 4178-4184.
    • (2000) J Immunol , vol.164 , Issue.8 , pp. 4178-4184
    • Idusogie, E.E.1    Presta, L.G.2    Santoro, G.3
  • 16
    • 0035865063 scopus 로고    scopus 로고
    • Engineered antibodies with increased activity to recruit complement
    • Idusogie EE, Pin YW, Leonard GP, et al. Engineered antibodies with increased activity to recruit complement. J Immunol 2001; 166(4): 2571-2575.
    • (2001) J Immunol , vol.166 , Issue.4 , pp. 2571-2575
    • Idusogie, E.E.1    Pin, Y.W.2    Leonard, G.P.3
  • 17
    • 29644434678 scopus 로고    scopus 로고
    • An engineered human IgG1 antibody with longer serum half-life
    • Hinton PR, Mary GJ, Joanna MX, et al. An engineered human IgG1 antibody with longer serum half-life. J Immunol 2006; 176(1): 346-56.
    • (2006) J Immunol , vol.176 , Issue.1 , pp. 346-356
    • Hinton, P.R.1    Mary, G.J.2    Joanna, M.X.3
  • 18
    • 27144465484 scopus 로고    scopus 로고
    • Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels
    • Vaccaro C, Jinchun Z, Raimund JO, Ward ES. Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels. Nat Biotechnol 2005; 23(10): 1283-1288.
    • (2005) Nat Biotechnol , vol.23 , Issue.10 , pp. 1283-1288
    • Vaccaro, C.1    Jinchun, Z.2    Raimund, J.O.3    Ward, E.S.4
  • 19
    • 70350763490 scopus 로고    scopus 로고
    • US20070041907
    • Ober, E.S.W.: US20070041907 (2007).
    • (2007)
    • Ober, E.S.W.1
  • 20
    • 70350755226 scopus 로고    scopus 로고
    • Larrick, J., William, K., Wycoff, L.: WO2001083529 (2001).
    • Larrick, J., William, K., Wycoff, L.: WO2001083529 (2001).
  • 21
    • 70350778223 scopus 로고    scopus 로고
    • Celada, F.: WO92005799 & WO2001920416 (1992).
    • Celada, F.: WO92005799 & WO2001920416 (1992).
  • 22
    • 0036960286 scopus 로고    scopus 로고
    • Cytokines in immunity and allograft rejection
    • Benjamin LC, Allan JS, Madsen JC. Cytokines in immunity and allograft rejection. Crit Rev Immunol 2002; 22(4): 269-279.
    • (2002) Crit Rev Immunol , vol.22 , Issue.4 , pp. 269-279
    • Benjamin, L.C.1    Allan, J.S.2    Madsen, J.C.3
  • 23
    • 39049088951 scopus 로고    scopus 로고
    • Dendritic cells and cytokines in human inflammatory and autoimmune diseases
    • Blanco P, Palucka AK, Pascual V, Banchereau J. Dendritic cells and cytokines in human inflammatory and autoimmune diseases. Cytokine Growth Factor Rev 2008; 19(1): 41-52.
    • (2008) Cytokine Growth Factor Rev , vol.19 , Issue.1 , pp. 41-52
    • Blanco, P.1    Palucka, A.K.2    Pascual, V.3    Banchereau, J.4
  • 27
    • 70350749032 scopus 로고    scopus 로고
    • Massberg, S.D., Gawaz, M., Bültmann, A., Münch, G., Ungerer, M., Peluso, M.: WO03104282 (2003).
    • Massberg, S.D., Gawaz, M., Bültmann, A., Münch, G., Ungerer, M., Peluso, M.: WO03104282 (2003).
  • 28
    • 23844546008 scopus 로고    scopus 로고
    • Stopping bacterial adhesion: A novel approach to treating infections
    • Bavington C, Page C. Stopping bacterial adhesion: A novel approach to treating infections. Respiration 2005; 72(4): 335-344.
    • (2005) Respiration , vol.72 , Issue.4 , pp. 335-344
    • Bavington, C.1    Page, C.2
  • 30
    • 70350759287 scopus 로고    scopus 로고
    • Staunton, D., Springer, E.T.A.: WO93006848 (1993).
    • Staunton, D., Springer, E.T.A.: WO93006848 (1993).
  • 31
    • 70350779821 scopus 로고    scopus 로고
    • Visintin, A., Goldenbock, D.T.: WO2007001332 (2007).
    • Visintin, A., Goldenbock, D.T.: WO2007001332 (2007).
  • 32
    • 70350770609 scopus 로고    scopus 로고
    • Larrick, J., William, K., Wycoff, L.: WO03064992 (2003).
    • Larrick, J., William, K., Wycoff, L.: WO03064992 (2003).
  • 33
    • 55849089267 scopus 로고    scopus 로고
    • Many cytokines are very useful therapeutic targets in disease
    • Feldmann M. Many cytokines are very useful therapeutic targets in disease. J Clin Invest 2008; 118(11): 3533-3536.
    • (2008) J Clin Invest , vol.118 , Issue.11 , pp. 3533-3536
    • Feldmann, M.1
  • 34
    • 38549161562 scopus 로고    scopus 로고
    • Fc-based cytokines: Prospects for engineering superior therapeutics
    • Jazayeri JA, Carroll GJ. Fc-based cytokines: Prospects for engineering superior therapeutics. BioDrugs 2008; 22(1): 11-26.
    • (2008) BioDrugs , vol.22 , Issue.1 , pp. 11-26
    • Jazayeri, J.A.1    Carroll, G.J.2
  • 35
    • 70350776115 scopus 로고
    • US5650150
    • Gillies, S.D.: US5650150 (1994).
    • (1994)
    • Gillies, S.D.1
  • 36
    • 70350779823 scopus 로고    scopus 로고
    • Harvill, E., Morrison, T.S.L.: WO030089 (1997).
    • Harvill, E., Morrison, T.S.L.: WO030089 (1997).
  • 37
    • 38449106700 scopus 로고    scopus 로고
    • Cytokine, chemokine, and co-stimulatory fusion proteins for the immunotherapy of solid tumors
    • Khawli LA, Hu P, Epstein AL. Cytokine, chemokine, and co-stimulatory fusion proteins for the immunotherapy of solid tumors. Handb Exp Pharmacol 2008; (181): 291-328
    • (2008) Handb Exp Pharmacol , vol.181 , pp. 291-328
    • Khawli, L.A.1    Hu, P.2    Epstein, A.L.3
  • 38
    • 70350745821 scopus 로고    scopus 로고
    • Capon, D., Gregory, J.T.J.: WO89002922 (1989).
    • Capon, D., Gregory, J.T.J.: WO89002922 (1989).
  • 39
    • 70350786026 scopus 로고    scopus 로고
    • Arathoon, R., Carter, P.J., Merchant, A.M., Presta, L.G.: WO98050431 (1998).
    • Arathoon, R., Carter, P.J., Merchant, A.M., Presta, L.G.: WO98050431 (1998).
  • 40
    • 0026781592 scopus 로고
    • Targeting of antitumor responses with bispecific antibodies
    • Segal DM, Qian JH, Mezzanzanica D, et al. Targeting of antitumor responses with bispecific antibodies. Immunobiol 1992; 185(2-4): 390-402
    • (1992) Immunobiol , vol.185 , Issue.2-4 , pp. 390-402
    • Segal, D.M.1    Qian, J.H.2    Mezzanzanica, D.3
  • 41
    • 0035251453 scopus 로고    scopus 로고
    • Bispecific human IgG by design
    • Carter P. Bispecific human IgG by design. J Immunol Methods 2001; 248(1-2): 7-15.
    • (2001) J Immunol Methods , vol.248 , Issue.1-2 , pp. 7-15
    • Carter, P.1
  • 42
    • 0029946383 scopus 로고    scopus 로고
    • Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization
    • Ridgway JB, Presta LG, Carter P. 'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization. Protein Eng 1996; 9(7): 617-621.
    • (1996) Protein Eng , vol.9 , Issue.7 , pp. 617-621
    • Ridgway, J.B.1    Presta, L.G.2    Carter, P.3
  • 43
    • 0028883643 scopus 로고
    • A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells
    • Chamow SM, Zhang DZ, Tan XY, et al. A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells. J Hematother 1995; 4(5): 439-446.
    • (1995) J Hematother , vol.4 , Issue.5 , pp. 439-446
    • Chamow, S.M.1    Zhang, D.Z.2    Tan, X.Y.3
  • 44
    • 0028883643 scopus 로고
    • A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells
    • Chamow SM, Zhang DZ, Tan XY, et al. A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells. J Hematother 1995; 4(5): 439-446.
    • (1995) J Hematother , vol.4 , Issue.5 , pp. 439-446
    • Chamow, S.M.1    Zhang, D.Z.2    Tan, X.Y.3
  • 45
    • 0025753131 scopus 로고
    • Bispecific antibodies that mediate killing of cells infected with human immunodeficiency virus of any strain
    • Berg J, Lotscher E, Steimer KS, et al. Bispecific antibodies that mediate killing of cells infected with human immunodeficiency virus of any strain. Proc Natl Acad Sci USA 1991; 88(11): 4723-4727.
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.11 , pp. 4723-4727
    • Berg, J.1    Lotscher, E.2    Steimer, K.S.3
  • 47
    • 0026698053 scopus 로고
    • The potential improvement of thrombolytic therapy by targeting with bispecific monoclonal antibodies: Why they are used and how they are made
    • Bos R, Nieuwenhuizen W. The potential improvement of thrombolytic therapy by targeting with bispecific monoclonal antibodies: Why they are used and how they are made. Biotherapy 1992; 5(3): 187-199.
    • (1992) Biotherapy , vol.5 , Issue.3 , pp. 187-199
    • Bos, R.1    Nieuwenhuizen, W.2
  • 48
    • 0037259397 scopus 로고    scopus 로고
    • Immune therapy for infectious diseases at the dawn of the 21st century: The past, present and future role of antibody therapy, therapeutic vaccination and biological response modifiers
    • Buchwald UK, Pirofski L. Immune therapy for infectious diseases at the dawn of the 21st century: the past, present and future role of antibody therapy, therapeutic vaccination and biological response modifiers. Curr Pharm Des 2003; 9(12): 945-968.
    • (2003) Curr Pharm Des , vol.9 , Issue.12 , pp. 945-968
    • Buchwald, U.K.1    Pirofski, L.2
  • 49
    • 62149133544 scopus 로고    scopus 로고
    • Fusion-proteins as biopharmaceuticals - applications and challenges
    • Schmidt, S.R., Fusion-proteins as biopharmaceuticals - applications and challenges. Curr Opin Drug Discov Dev 2009; 12(2): 284-295.
    • (2009) Curr Opin Drug Discov Dev , vol.12 , Issue.2 , pp. 284-295
    • Schmidt, S.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.