Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic mice, an animal model of Cushing syndrome

Endocrine Journal

Volumn 56, Issue 7, 2009, Pages 879-886

  Shinahara, Masayuki ^a   Nishiyama, Mitsuru ^a   Iwasaki, Yasumasa ^a   Nakayama, Shuichi ^a   Noguchi, Toru ^a   Kambayashi, Machiko ^a   Okada, Yasushi ^a   Tsuda, Masayuki ^a   Stenzel Poore, Mary P ^b   Hashimoto, Kozo ^a   Terada, Yoshio ^a  

^a KOCHI UNIVERSITY   (Japan)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Adiponectin; Cushing syndrome; Glucocorticoid; Insulin resistance; Obesity

Indexed keywords

ADIPONECTIN; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR;

ADIPOSE TISSUE; ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CUSHING SYNDROME; GLUCOSE METABOLISM; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN;

ADIPONECTIN; ANIMALS; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; CUSHING SYNDROME; DISEASE MODELS, ANIMAL; INSULIN RESISTANCE; MALE; MICE; MICE, TRANSGENIC;

EID: 70350676818     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K09E-038     Document Type: Article

References (35)

1. Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, Marks JS (2003) Prevalence of obesity, diabetes and obesity-related health risk factors, 2001. JAMA 289: 76-79. (Pubitemid 36026281)
2. Reaven GM (2005) The insulin resistance syndrome: definition and dietary approaches to treatment. Annu Rev Nutr 25: 391-406. (Pubitemid 41209007)
3. Ronti T, Lupattelli G, Mannarino E (2006) The endocrine function of adipose tissue: an update. Clin Endocrinol 64: 355-365.
4. Schenk S, Saberi M, Olefsky JM (2008) Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 118: 2992-3002.
5. Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830. (Pubitemid 38063705)
6. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AWJ (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112: 1796-1808. (Pubitemid 38063703)
7. Arnaldi G, Angeli A, Atkinson AB, Bertagna X, Cavagnini F, Chrousos GP, Fava GA, Findling JW, Gaillard RC, Grossman AB, Kola B, Lacroix A, Mancini T, Mantero F, Newell-Price J, Nieman LK, Sonino N, Vance ML, Giustina A, Boscaro M (2003) Diagnosis and complications of Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab 88: 5593-5602. (Pubitemid 38033020)
8. Masuzaki H, Paterson J, Shinyama H, Morton NM, Seckl JR, Flier JS (2001) A transgenic model of visceral obesity and the metabolic syndrome. Science 94: 2166-2170. (Pubitemid 33150673)
9. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Lavery GG, Cooper MS, Hewison M, Stewart PM (2004) 11β-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocrine Reviews 25: 831-866. (Pubitemid 39366049)
10. Shojima N, Sakoda H, Ogihara T, Fujishiro M, Katagiri H, Anai M, Onishi Y, Ono H, Inukai K, Abe M, Fukushima Y, Kikuchi M, Oka Y, Asano T (2002) Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells. Diabetes 51: 1737-1744. (Pubitemid 34564285)
11. Krsek M, Silha JV, Jezkova J, Hana V, Marek J, Weiss V, Stepan JJ, Murphy LJ (2004) Adipokine levels in Cushing's syndrome: elevated resistin levels in female patients with Cushing's syndrome. Clin Endocrinol 60: 350-357. (Pubitemid 38297126)
12. Hu E, Liang P, Spiegelman BM (1996) AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271: 10697-10703. (Pubitemid 26145805)
13. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K (1996) cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 221: 286-289. (Pubitemid 26136463)
14. Nakano Y, Tobe T, Choi-Miura NH, Mazda T, Tomita M (1996) Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem (Tokyo) 120: 803-812. (Pubitemid 26385421)
15. Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF (1995) A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270: 26746-26749.
16. Kadowaki T, Yamauchi T (2005) Adiponectin and adiponectin receptors. Endocr Rev 26: 439-451.
17. Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K (2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116: 1784-1792. (Pubitemid 44033298)
18. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y (1999) Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257: 79-83. (Pubitemid 29299050)
19. Yatagai T, Nagasaka S, Taniguchi A, Fukushima M, Nakamura T, Kuroe A, Nakai Y, Ishibashi S (2003) Hypoadiponectinemia is associated with visceral fat accumulation and insulin resistance in Japanese men with type 2 diabetes mellitus. Metabolism 52: 1274-1278. (Pubitemid 37351094)
20. Lindsay RS, Funahashi T, Hanson RL, Matsuzawa Y, Tanaka S, Tataranni PA, Knowler WC, Krakoff J (2002) Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 360: 57-58. (Pubitemid 34756495)
21. Spranger J, Kroke A, Mohlig M, Bergmann MM, Ristow M, Boeing H, Pfeiffer AF (2003) Adiponectin and protection against type 2 diabetes mellitus. Lancet 361: 226-228. (Pubitemid 36126226)
22. Fasshauer M, Klein J, Neumann S, Eszlinger M, Paschke R (2002) Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun 290: 1084-1089. (Pubitemid 34687474)
23. Degawa-Yamauchi M, Moss KA, Bovenkerk JE, Shankar SS, Morrison CL, Lelliott CJ, Vidal-Puig A, Jone R, Considine RV (2005) Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha. Obesity Res 13: 662-669.
24. Fallo F, Scarda A, Sonino N, Paoletta A, Boscaro M, Pagano C, Federspil G, Vettor R (2004) Effect of glucocorticoids on adiponectin: a study in healthy subjects and in Cushing's syndrome. Eur J Endocrinol 150: 339-344. (Pubitemid 38443784)
25. Lewandowski KC, Szosland K, Lewinski A (2006) Short-term dexamethasone administration does not alter serum adiponectin or resistin concentrations in overweight and obese subjects despite an increase in insulin resistance. Clin Endocrinol 65: 551-552. (Pubitemid 44414284)
26. Stenzel-Poore MP, Cameron VA, Vaughan J, Sawchenko PE, Vale WW (1992) Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice. Endocrinology 130: 3378-3386.
27. Bruun JM, Jihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B (2003) Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 285: E527-533. (Pubitemid 37010830)
28. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T (2001) The fat-derived hormone adoponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7: 941-946. (Pubitemid 32756432)
29. Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, Takata M, Eto K, Terauchi Y, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Naitoh T, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T (2003) Globular adiponectin protected ob/ob mice from diabetes and apoE-deficient mice from atherosclerosis. J Biol Chem 278: 2461-2468. (Pubitemid 36801322)
30. Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T (2004) Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 279: 30817-30822. (Pubitemid 38938015)
31. Libe R, Morpurgo PS, Cappiello V, Maffini A, Bondioni S, Locatelli M, Zavanone M, Beck-Peccoz P, Spada A (2005) Ghrelin and adiponectin in patients with Cushing's disease before and after successful transsphenoidal surgery. Clin Endocrinol 62: 30-36. (Pubitemid 40175280)
32. Darman P, Dadoun F, Boullu-Ciocca S, Grino M, Alessi MC, Dutour A (2006) Insulin resistance induced by hydrocortisone is increased in patients with abdominal obesity. Am J Physiol Endocrinol Metab 291: E995-E1002. (Pubitemid 44776749)
33. Uchida HA, Nakayama Y, Kaihara M, Norii H, Hanayama Y, Sugiyama H, Maeshima Y, Yamasaki Y, Makino H (2006) Steroid pulse therapy impaired endothelial function while increasing plasma high molecule adiponectin concentration in patients with IgA nephropathy. Nephrol Dial Transplant 21: 3475-3480. (Pubitemid 44817097)
34. Wang ZV, Schraw TD, Kim JY, Khan T, Rajala MW, Follenzi A, Scherer PE (2007) Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retension. Mol Cell Biol 27: 3716-3731. (Pubitemid 46726179)
35. Wang Y, Lam KS, Yau MH, Xu A (2008) Posttranslational modifications of adiponectin: mechanisms and functional implications. Biochem J 409: 623-633. (Pubitemid 351214189)