Effect of glucocorticoids on adiponectin: A study in healthy subjects and in Cushing's syndrome

European Journal of Endocrinology

Volumn 150, Issue 3, 2004, Pages 339-344

  Fallo, Francesco ^a   Scarda, Alessando ^a   Sonino, Nicoletta ^a   Paoletta, Agostino ^b   Boscaro, Marco ^c   Pagano, Claudio ^a   Federspil, Giovanni ^a   Vettor, Roberto ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b City Hospital   (Italy)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCOCORTICOID; GLUCOSE; HYDROCORTISONE SODIUM SUCCINATE; INSULIN; LIPID;

ADULT; AGE DISTRIBUTION; ANTHROPOMETRY; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD SAMPLING; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; CUSHING SYNDROME; DOSE RESPONSE; DRUG ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HUMAN; HYDROCORTISONE RELEASE; HYDROCORTISONE URINE LEVEL; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; MALE; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX DIFFERENCE;

ADIPONECTIN; ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; CASE-CONTROL STUDIES; CUSHING SYNDROME; FEMALE; HUMANS; HYDROCORTISONE; INSULIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LINEAR MODELS; MALE; MIDDLE AGED; OBESITY; PROTEINS;

EID: 1842422404     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1500339     Document Type: Article

References (33)

1. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y & Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant Gene transcript 1). Biochemical and Biophysical Research Communications 1996 221 286-289.
2. Diez JJ & Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. European Journal of Endocrinology 2003 148 293-300.
3. Andrews RC & Walker BR. Glucocorticoids and insulin resistance: Old hormones, new targets. Clinical Science 1999 96 513-523.
4. Colao A, Pivonello R, Spiezia S, Faggiano A, Ferone D, Filippella M et al. Persistence of increased cardiovascular risk in patients with Cushing's disease after five years of successful cure. Journal of Clinical Endocrinology and Metabolism 1999 84 2664-2672.
5. Lindholm J, Juul S, Jorgensen JOL, Astrup J, Bjerre P, Feldt-Rasmussen U et al. Incidence and late prognosis of Cushing's syndrome. A population-based study. Journal of Clinical Endocrinology and Metabolism 2001 86 117-123.
6. Boscaro M, Barzon L, Fallo F & Sonino N. Cushing's syndrome. Lancet 2001 357 783-791.
7. Fasshauer M, Klein J, Neumann S. Eszlinger M & Paschke R. Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications 2002 290 1084-1089.
8. Halleux CM, Takahashi M, Delporte ML, Detry R, Funahashi T, Matsuzawa Y et al. Secretion of adiponectin and regulation of apM1 gene expression in human adipose visceral tissue. Biochemical and Biophysical Research Communications 2001 288 1102-1107.
9. Makimura H, Mizuno TM, Bergen H & Mobbs CV. Adiponectin is stimulated by adrenalectomy in ob/ob mice and is highly correlated with resistin mRNA. American Journal of Physiology-Endocrinology and Metabolism 2002 283 E1266-E1271.
10. Comuzzie AG, Funahashi T, Sonnenberg G, Martin LJ, Jacob HJ, Kwitek Black AE et al. The genetic basis of plasma variation in adiponectin, a global phenotype for obesity and the metabolic syndrome. Journal of Clinical Endocrinology and Metabolism 2001 86 4321-4325.
11. Boscaro M. Paoletta A, Scarpa E, Barzon L, Fusaro P, Fallo F et al. Age-related changes in glucocorticoid fast feedback inhibition of adrenocorticotropin in man. Journal of Clinical Endocrinology and Metabolism 1998 83 1380-1383.
12. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1998 1 (Suppl 1) S5-S19.
13. National Institutes of Health, National Heart, Lung and Blood Institute. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report. Obesity Research 1998 6 (Suppl 2) S51-S210.
14. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC. Homeostasis; model assessment: Insulin resistance and β -cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 1985 28 412-419.
15. Emoto M, Nishizawa Y, Maekava K, Hiura Y, Kanda H, Kawagishi T et al. Homeostasis model of assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care 1999 22 818-822.
16. Pannacciulli N, Vettor R, Milan G, Granzotto M, Catucci A, Federspil G et al. Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism. Journal of Clinical Endocrinology and Metabolism 2003 88 1748-1752.
17. Derendorf H, Mollmann H, Barth J, Mollmann C, Tunn S & Krieh M. Pharmacokinetics and oral bioavailability of hydrocortisone. Journal of Clinical Pharmacology 1991 31 473-476.
18. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE et al. Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia. Journal of Clinical Endocrinology and Metabolism 2001 86 1930-1935.
19. Yu JG, Javorski S, Hevener AL, Kruszynska YT, Norman RA, Sinha M et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese and type 2 diabetic subjects. Diabetes 2002 51 2968-2974.
20. Kern PA, Gregorio G, Lu T, Rassouli N & Ranganathan G. Adiponectin expression from human adipose tissue. Relation to obesity, insulin resistance. and tumor necrosis factor-α expression. Diabetes 2003 52 1779-1785.
21. Reaven GM. Banting Lecture 1988: Role of insulin resistance in human disease. Diabetes 1988 37 1595-1607.
22. DeFronzo RA & Ferrannini E. Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991 14 173-194.
23. Holmang A & Biorntop P. The effects of cortisol on insulin sensitivity in muscle. Acta Physiologica Scandinavica 1992 144 425-431.
24. Dinneen S, Alzaid A, Miles J & Rizza R. Metabolic effects of the nocturnal rise in cortisol in carbohydrate metabolism in normal subjects. Journal of Clinical Investigation 1993 92 2283-2290.
25. Bjorntorp P & Rosmond R. Obesity and cortisol. Nutrition 2000 16 924-936.
26. Khani S & Tayek JA. Cortisol increases gluconeogenesis in humans: Its role in the metabolic syndrome. Clinical Science 2001 101 739-747.
27. Ullian ME. The role of corticosteroids in the regulation of vascular tone. Cardiovascular Research 1999 41 55-64.
28. Boscaro M, Sonino N, Scarda A, Barzon L, Fallo F, Sartori MT et a]. Anticoagulant prophylaxis markedly reduced thromboembolic complications in Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 2002 87 3662-3666.
29. Whitworth JA, Mangos GJ & Kelly JJ. Cushing, cortisol and cardiovascular disease. Hypertension 2000 36 912-916.
30. Masuzaki H, Ogawa Y, Hosoda K, Miyawaki T. Hanaoka I, Hiraoka J et a]. Glucorticoid regulation of leptin synthesis and secretion in humans: Elevated plasma leptin levels in Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 1997 82 2542-2547.
31. Widiaja A, Schurmeyer TH, Von zur Muhlen A & Brabant G. Determinants of serum leptin levels in Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 1998 83 600-603.
32. Rockall AG, Sohaib SA, Evans D, Kaltsas G, Isidori AM, Monson JP et al. CT assessment of fat distribution in male and female patients with Cushing's syndrome. European Journal of Endocrinology 2003 149 561-567.
33. Ukkola O & Santaniemi M. Adiponectin: A link between excess adiposity and associated comorbidities? Journal of Molecular Medicine 2002 80 696-702.