Dissolution rate enhancement of the poorly water-soluble drug Tibolone using PVP, SiO2, and their nanocomposites as appropriate drug carriers Tibolone solid dispersions

Drug Development and Industrial Pharmacy

Volumn 35, Issue 9, 2009, Pages 1128-1138

  Papadimitriou, Sofia ^a   Bikiaris, Dimitrios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Dissolution rate enhancement; PVP; Silica nanoparticles; Solid dispersion; Tibolone

Indexed keywords

NANOCOMPOSITE; POVIDONE; SILICON DIOXIDE; TIBOLONE; WATER;

ARTICLE; CONCENTRATION (PARAMETERS); CRYSTALLIZATION; DISPERSION; DRUG SOLUBILITY; EVAPORATION; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION;

CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; KINETICS; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; NORPREGNENES; PARTICLE SIZE; PHARMACEUTIC AIDS; POVIDONE; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SILICON DIOXIDE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 70350668808     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040902787653     Document Type: Article

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