Bioequivalence studies and sugar-based excipients effects on the properties of new generic ketoconazole tablets formulations and stability evaluation by using direct compression method Effect of superdisintegrants on ketoconazole tablets A.L. Viosa et al.

Pharmaceutical Development and Technology

Volumn 14, Issue 5, 2009, Pages 530-539

  Viçosa, Alessandra L ^a,b   Chatah, Eliane N ^c   Santos, Tereza C ^b   Jones Jnr, Luiz F ^a   Dantas, Cide B ^a   Dornelas, Camila B ^a   Rodrigues, Carlos R ^a   Castro, Helena C ^d   Sousa, Valria P ^a   Dias, Luiza R S ^d   Cabral, Lúcio M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Abbott Brazil   (Brazil)

^d FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Direct compression; Dissolution; Ketoconazole; Polyols; Sugar based excipients and superdisintegrants

Indexed keywords

ADVANTOSE 100; CROSCARMELLOSE SODIUM; CROSPOVIDONE; EXCIPIENT; GENERIC DRUG; ISOMALT; KETOCONAZOLE; LACTITOL; LACTOSE; MAGNESIUM STEARATE; MALTITOL; MALTOSE; MANNITOL; MICROCRYSTALLINE CELLULOSE; PARTECK M 200; POLYOL; POVIDONE; SILICON DIOXIDE; SODIUM METABISULFITE; SORBITOL; STARCH GLYCOLATE SODIUM; UNCLASSIFIED DRUG; XYLITOL; XYLITOL CM;

ARTICLE; BIOEQUIVALENCE; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; DRUG STABILITY; EXCIPIENT COMPATIBILITY; HUMAN; HUMAN EXPERIMENT; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; TABLET COMPRESSION; TABLET DISINTEGRATION; TABLET FORMULATION;

ANTIFUNGAL AGENTS; CARBOXYMETHYLCELLULOSE; DRUG STABILITY; EXCIPIENTS; HARDNESS; HUMANS; KETOCONAZOLE; MALTOSE; SOLUBILITY; TABLETS; THERAPEUTIC EQUIVALENCY;

EID: 70350656250     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450902832877     Document Type: Article

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