Stem cell therapy for cartilage regeneration in osteoarthritis

Expert Opinion on Biological Therapy

Volumn 9, Issue 11, 2009, Pages 1399-1405

  Koelling, Sebastian ^a   Miosge, Nicolai ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Cartilage repair; Chondrogenic progenitor cells; Regeneration; Stem cells

Indexed keywords

ARTICULAR CARTILAGE; CELL DIFFERENTIATION; CELL POPULATION; CHONDROGENESIS; EMBRYONIC STEM CELL; HUMAN; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOARTHRITIS; REVIEW; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; TISSUE REPAIR;

CARTILAGE; CELL DIFFERENTIATION; HUMANS; OSTEOARTHRITIS; REGENERATION; STEM CELL TRANSPLANTATION;

EID: 70350635525     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712590903246370     Document Type: Review

References (58)

1. Buckwalter JA, Mankin HJ. Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr Course Lect 1998;47:487-504
2. Horton WE Jr, Bennion P, Yang L. Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis. J Musculoskelet Neuronal Interact 2006;6:379-381 (Pubitemid 46099725)
3. Lohmander LS, Roos EM. Clinical update: treating osteoarthritis. Lancet 2007;370:2082-2084
4. Reginster JY. The prevalence and burden of arthritis. Rheumatology (Oxford) 2002;41(Supp 1):3-6
5. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ 2003;81:646-656
6. O'Rahilly R, Bossy J, Muller F. Introduction to the study of embryonic stages in man. Bull Assoc Anat (Nancy) 1981;65:141-236
7. Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147
8. Blum B, Benvenisty N. Clonal analysis of human embryonic stem cell differentiation into teratomas. Stem Cells 2007;25:1924-1930 (Pubitemid 47258170)
9. Burton PM. Insights from diploblasts; the evolution of mesoderm and muscle. J Exp Zoolog B Mol Dev Evol 2008;310:5-14
10. Winslow BB, Takimoto-Kimura R, Burke AC. Global patterning of the vertebrate mesoderm. Dev Dyn 2007;236:2371-2381
11. Wellik DM. Hox patterning of the vertebrate axial skeleton. Dev Dyn 2007;236:2454-2463 (Pubitemid 47450935)
12. Ochi H, Westerfield M. Signaling networks that regulate muscle development: lessons from zebrafish. Dev Growth Differ 2007;49:1-11 (Pubitemid 46066480)
13. Pacifici M, Koyama E, Shibukawa Y, et al. Cellular and molecular mechanisms of synovial joint and articular cartilage formation. Ann NY Acad Sci 2006;1068:74-86 (Pubitemid 43824138)
14. da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 2006;119:2204-2213 (Pubitemid 43960310)
15. Kassem M, Abdallah BM. Human bone-marrow-derived mesenchymal stem cells: biological characteristics and potential role in therapy of degenerative diseases. Cell Tissue Res 2008;331:157-163 (Pubitemid 350265499)
16. Barbero A, Ploegert S, Heberer M, Martin I. Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes. Arthritis Rheum 2003;48:1315-1325 (Pubitemid 36554530)
17. Dell'Accio F, Vanlauwe J, Bellemans J, et al. Expanded phenotypically stable chondrocytes persist in the repair tissue and contribute to cartilage matrix formation and structural integration in a goat model of autologous chondrocyte implantation. J Orthop Res 2003;21:123-131 (Pubitemid 36157629)
18. Liu G, Kawaguchi H, Ogasawara T, et al. Optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes. J Biol Chem 2007;282:20407-20415 (Pubitemid 47100026)
19. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676 (Pubitemid 44233629)
20. Fuchs E, Tumbar T, Guasch G. Socializing with the neighbors: stem cells and their niche. Cell 2004;116:769-778 (Pubitemid 38410723)
21. Fuchs E. Skin stem cells: rising to the surface. J Biol Chem 2008;180:273-284 (Pubitemid 351185914)
22. Bianco P, Robey PG. Stem cells in tissue engineering. Nature 2001;414:118-121
23. Ho AD, Wagner W. The beauty of asymmetry: asymmetric divisions and self-renewal in the haematopoietic system. Curr Opin Hematol 2007;14:330-336 (Pubitemid 46842806)
24. Sacchetti B, Funari A, Michienzi S, et al. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007;131:324-336 (Pubitemid 47592917)
25. Bi Y, Ehirchiou D, Kilts TM, et al. Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med 2007;13:1219-1227 (Pubitemid 47530625)
26. Friedenstein AJ, Chailakhjan RK, Lalykina KS. The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet 1970;3:393-403
27. Johnstone B, Hering TM, Caplan AI, et al. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res 1998;238:265-272
28. Mackay AM, Beck SC, Murphy JM, et al. Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow. Tissue Eng 1998;4:415-428 (Pubitemid 28553528)
29. Sekiya I, Colter DC, Prockop DJ. BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells. Biochem Biophys Res Commun 2001;284:411-418 (Pubitemid 32917992)
30. Gronthos S, Zannettino AC, Hay SJ, et al. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. J Cell Sci 2003;116:1827-1835 (Pubitemid 36582169)
31. De Bari C, Dell'Accio F, Luyten FP. Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo. Arthritis Rheum 2004;50:142-150 (Pubitemid 38084298)
32. Jones EA, English A, Henshaw K, et al. Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis. Arthritis Rheum 2004;50:817-827 (Pubitemid 38326182)
33. English A, Jones EA, Corscadden D, et al. A comparative assessment of cartilage and joint fat pad as a potential source of cells for autologous therapy development in knee osteoarthritis. Rheumatology 2007;46:1676-1683 (Pubitemid 350018489)
34. Khan WS, Adesida AB, Hardingham TE. Hypoxic conditions increase hypoxia inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients. Arthritis Res Ther 2007;9:R55
35. Tuan RS, Boland G, Tuli R. Adult mesenchymal stem cells and cell-based tissue engineering. Arthritis Res Ther 2003;5:32-45 (Pubitemid 36849748)
36. Murphy JM, Fink DJ, Hunziker EB, Barry FP. Stem cell therapy in a caprine model of osteoarthritis. Arthritis Rheum 2003;48:3464-3474 (Pubitemid 37531912)
37. Figeac N, Daczewska M, Marcelle C, Jagla K. Muscle stem cells and model systems for their investigation. Dev Dyn 2007;236:3332-3342 (Pubitemid 350276390)
38. Ortak T, Ozdemir R, Uysal A, et al. Osteogenic capacities of periost grafts, periost flaps and prefabricated periosteal flaps: experimental study. J Craniofac Surg 2005;16:594-600 (Pubitemid 41271245)
39. Pridie KH. The development and nature of osteoarthritis of the hip joint. Rheumatism 1955;11:2-7
40. Simon TM, Jackson DW. Articular cartilage: injury pathways and treatment options. Sports Med Arthrosc 2006;14:146-154 (Pubitemid 44243889)
41. Sandell LJ, Aigner T. Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis. Arthritis Res 2001;3:107-113
42. Tesche F, Miosge N. New aspects of the pathogenesis of osteoarthritis: the role of fibroblast-like chondrocytes in late stages of the disease. Histol Histopathol 2005;20:329-337 (Pubitemid 40029009)
43. Miosge N, Hartmann M, Maelicke C, Herken R. Expression of collagen type I and type II in consecutive stages of human osteoarthritis. Histochem Cell Biol 2004;122:229-236 (Pubitemid 39371492)
44. Miosge N, Waletzko K, Bode C, et al. Light and electron microscopic in-situ hybridization of collagen type I and type II mRNA in the fibrocartilaginous tissue of late-stage osteoarthritis. Osteoarthritis Cartilage 1998;6:278-285 (Pubitemid 28341742)
45. Alsalameh S, Amin R, Gemba T, Lotz M. Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage. Arthritis Rheum 2004;50:1522-1532 (Pubitemid 38608074)
46. Fickert S, Fiedler J, Brenner RE. Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers. Arthritis Res Ther 2004;6:R422-32
47. Hiraoka K, Grogan S, Olee T, Lotz M. Mesenchymal progenitor cells in adult human articular cartilage. Biorheology 2006;43:447-454 (Pubitemid 44221924)
48. Dowthwaite GP, Bishop JC, Redman SN, et al. The surface of articular cartilage contains a progenitor cell population. J Cell Sci 2004;117:889-897
49. Koelling S, Kruegel J, Irmer M, et al. Migratory chondrogenic progenitor cells from repair tissue during the late stages of human osteoarthritis. Cell Stem Cell 2009;4:324-335
50. Babaie Y, Herwig R, Greber B, et al. Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells 2007;25:500-510 (Pubitemid 46232806)
51. Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol 2007;25:1177-1181 (Pubitemid 47538112)
52. Nakagawa M, Koyanagi M, Tanabe K, et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2007;26:101-106
53. Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872 (Pubitemid 350138099)
54. Wernig M, Meissner A, Foreman R, et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007;448:318-324
55. Zhou H, Wu S, Joo JY, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4:381-384
56. Shi Y, Desponts C, Do JT, et al. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 2008;3:568-574
57. Fuchs E. Finding one's nice in the skin. Cell Stem Cell 2009;4:499-502
58. Murphy LM, Dixon K, Beck S, et al. Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum 2002;46:704-713 (Pubitemid 34218142)