Is there a role for complementary therapy in the management of leukemia?

Expert Review of Anticancer Therapy

Volumn 9, Issue 9, 2009, Pages 1241-1249

  Wesa, Kathleen M ^a   Cassileth, Barrie R ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Acupuncture; Botanical supplements; Cancer; Complementary therapies; Leukemia; Massage therapy; Mind body therapies; Nutrition; Physical fitness

Indexed keywords

AGARICUS EXTRACT; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BORTEZOMIB; CALCIUM; EPIGALLOCATECHIN GALLATE; FOLIC ACID; GREEN TEA EXTRACT; HEPARIN; MULTIVITAMIN; PACLITAXEL; PLACEBO; PLANT EXTRACT; SELENIUM; UNCLASSIFIED DRUG; VITAMIN; VITAMIN D; WARFARIN;

ACUPUNCTURE; AGARICUS; ALTERNATIVE MEDICINE; AYURVEDA; CANCER THERAPY; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; DIABETES MELLITUS; DIETARY INTAKE; DRUG ANTAGONISM; DRUG DOSE INCREASE; DRUG MECHANISM; DRUG MEGADOSE; DRUG WITHDRAWAL; EXERCISE; FITNESS; GUIDED IMAGERY; HEAD AND NECK CANCER; HEALTH CARE COST; HERBAL MEDICINE; HOMEOPATHY; HUMAN; HYPNOSIS; INTERMETHOD COMPARISON; INTERVENTION STUDY; LEUKEMIA; LIFESTYLE MODIFICATION; LUNG CANCER; MALIGNANT NEOPLASTIC DISEASE; MASSAGE; MEDICINAL PLANT; MEDITATION; MULTIPLE MYELOMA; MUSIC THERAPY; NONHUMAN; NUTRITIONAL STATUS; OVERALL SURVIVAL; PERIPHERAL NEUROPATHY; PHYSICAL ACTIVITY; PREVALENCE; QUALITY OF LIFE; REFLEXOLOGY; REVIEW; RISK ASSESSMENT; RISK REDUCTION; SURVIVAL TIME; TAI CHI; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; VITAMIN SUPPLEMENTATION; YOGA;

ANIMALS; COMPLEMENTARY THERAPIES; HUMANS; LEUKEMIA; PHYSICAL FITNESS; QUALITY OF LIFE; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 70350633929     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/ERA.09.100     Document Type: Review

References (67)

1. Vickers AJ, Kuo J, Cassileth BR. Unconventional anticancer agents: a systematic review of clinical trials. J. Clin. Oncol. 24(1), 136-140 (2006). •• Cogent analysis of clinical trials using unconventional anticancer therapies, including botanicals, high-dose nutritional supplements, off-label pharmaceuticals and animal products. (Pubitemid 46630504)
2. Bairati I, Meyer F, Gélinas M et al. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. J. Clin. Oncol. 23(24), 5805-5813 (2005). (Pubitemid 46300177)
3. Bairati I, Meyer F, Jobin E et al. Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients. Int. J. Cancer 119(9), 2221-2224 (2006). (Pubitemid 44423684)
4. Styczynski J, Wysocki M. Alternative medicine remedies might stimulate viability of leukemic cells. Pediatr. Blood Cancer 46(1), 94-98 (2006). (Pubitemid 41779324)
5. Gupta M, Shafiq N, Kumari S, Pandhi P. Patterns and perceptions of complementary and alternative medicine (CAM) among leukaemia patients visiting haematology clinic of a north Indian tertiary care hospital. Pharmacoepidemiol. Drug Saf. 11(8), 671-676 (2002). (Pubitemid 35469362)
6. Hensel M, Zoz M, Ho AD. Complementary and alternative medicine in patients with chronic lymphocytic leukemia. Support. Care Cancer 17(1), 47-52 (2009).
7. Corner J, Yardley J, Maher EJ et al. Patterns of complementary and alternative medicine use among patients undergoing cancer treatment. Eur. J. Cancer Care 18(3), 271-279 (2009).
8. Sencer SF, Kelly KM. Bringing evidence to complementary and alternative medicine for children with cancer. J. Pediatr. Hematol. Oncol. 28(3), 186-189 (2006).
9. Fernandez C, Pyesmany A, Stutzer C. Alternative therapies in childhood cancer. N. Engl. J. Med. 340(7), 569-570 (1999).
10. Kelly KM. Bringing evidence to complementary and alternative medicine in children with cancer: focus on nutrition-related therapies. Pediatr. Blood Cancer 50(2 Suppl.), 490-493 (2008). • Succinct review of pediatric cancer nutritional supplements use and special issues encountered with these agents in pediatric oncology.
11. Fernandez CV, Stutzer CA, MacWilliam L, Fryer C. Alternative and complementary therapy use in pediatric oncology patients in British Columbia: prevalence and reasons for use and nonuse. J. Clin. Oncol. 16(4), 1279-1286 (1998). (Pubitemid 28175740)
12. Ezzo J, Vickers A, Richardson MA et al. Acupuncture-point stimulation for chemotherapy-induced nausea and vomiting. J. Clin. Oncol. 23(28), 7188-7198 (2005). (Pubitemid 46260306)
13. Wong R, Sagar S. Acupuncture treatment for chemotherapy-induced peripheral neuropathy - a case series. Acupunct. Med. 24(2), 87-91 (2006). (Pubitemid 44048896)
14. Cassileth BR, Vickers AJ. Massage therapy for symptom control: outcome study at a major cancer center. J. Pain Symptom Manage. 28(3), 244-249 (2004).
15. Stringer J, Swindell R, Dennis M. Massage in patients undergoing intensive chemotherapy reduces serum cortisol and prolactin. Psychooncology 17(10), 1024-1031 (2008).
16. Sagar SM. Acupuncture as an evidence-based option for symptom control in cancer patients. Curr. Treat. Options Oncol. 9(2-3), 117-126 (2008). •• Review of acupuncture clinical trials for symptom control in oncology patients.
17. Lehmann C, Pavlovic D, Dinse M, Usichenko TI. Hemorrage after auricular acupuncture due to postoperative dilutional thrombocytopenia. Anesth. Analg. 103(5), 1333-1334 (2006). (Pubitemid 44627381)
18. Cummings M, Liu D, Ooman S. Acupuncture for acute postoperative pain relief in a patient with pregnancy-induced thrombocytopenis. Acupuncture in Medicine 23(2), 83-85 (2005). (Pubitemid 40978887)
19. Deng G, Hou BL, Holodny AI, Cassileth BR. Functional magnetic resonance imaging (fMRI) changes and saliva production associated with acupuncture at LI-2 acupuncture point: a randomized controlled study. BMC Complement. Altern. Med. 8, 37 (2008).
20. Garcia MK, Chiang JS, Cohen L et al. Acupuncture for radiation-induced xerostomia in patients with cancer: a pilot study. Head Neck DOI: 10.1002/hed.21110 (2009) (Epub ahead of print).
21. Deng G, Vickers A, Yeung S et al. Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients. J. Clin. Oncol. 25(35), 5584-5590 (2007).
22. Borud EK, Alraek T, White A et al. The acupuncture on hot flushes among menopausal women (ACUFLASH) study, a randomized controlled trial. Menopause 16(3), 484-493 (2009).
23. Chong L-Y, Treasure T. Acupuncture to relieve the pain of thoracotomy: commentary on randomized, controlled trial. J. Thorac. Cardiovasc. Surg. 136(6), 1470-1471 (2008).
24. Carlson LE, Bultz BD. Mind-body interventions in oncology. Curr. Treat. Options Oncol. 9(2-3), 127-134 (2008).
25. Montgomery GH, Bovbjerg DH, Schnur JB et al. A randomized clinical trial of a brief hypnosis intervention to control side effects in breast surgery patients. J. Natl Cancer Inst. 99(17), 1304-1312 (2007).
26. Cassileth BR, Vickers AJ, Magill LA. Music therapy for mood disturbance during hospitalization for autologous stem cell transplantation: a randomized controlled trial. Cancer 98(12), 2723-2729 (2003).
27. Sahler OJZ, Hunter BC, Liesveld JL. The effect of using music therapy with relaxation imagery in the management of patients undergoing bone marrow transplantation: a pilot feasibility study. Altern. Ther. Health Med. 9(6), 70-74 (2003).
28. Kelly KM. Complementary and alternative medicines for use in supportive care in pediatric cancer. Support. Care Cancer 15(4), 457-460 (2007).
29. Shanafelt TD, Lee YK, Call TG et al. Clinical effects of oral green tea extracts in four patients with low grade B-cell malignancies. Leuk. Res. 30(6), 707-712 (2006).
30. Werneke U, Earl J, Seydel C et al. Potential health risks of complementary alternative medicines in cancer patients. Br. J. Cancer 90(2), 408-413 (2004). (Pubitemid 38250637)
31. Shanafelt TD, Call TG, Zent CS et al. Phase I trial of daily oral polyphenon E in Patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. J. Clin. Oncol. 27(23), 3808-3814 (2009).
32. Golden EB, Lam PY, Kardosh A et al. Green tea polyphenols block the anticancer effects of bortozemib and other boronic acid-based proteasome inhibitors. Blood 112(23), 5927-5937(2009).
33. Kim CF, Jiang JJ, Leung KN, Fung KP, Lau CBS. Inhibitory effects of agaricus blazei extracts on human myeloid leukemia cells. J. Ethnopharmacol. 122(2), 320-326 (2009).
34. Lin J, Cook NR, Albert C et al. Vitamins C and E and β carotene supplementation and cancer risk: a randomized controlled trial. J. Natl Cancer Inst. 101(1), 14-23 (2009).
35. Gaziano JM, Glynn RJ, Christen WG et al. Vitamins E and C in the prevention of prostate and total cancer in men: the physicians' health study II randomized controlled trial. JAMA 301(1), 52-62 (2009).
36. Lippman SM, Klein EA, Goodman PJ et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT). JAMA 301(1), 39-51 (2009).
37. Perrone G, Hideshima T, Ikeda H et al. Ascorbic acid inhibits antitumor activity of bortezomib in vivo. Leukemia DOI: 10.1038/leu.2009.83 (2009) (Epub ahead of print).
38. Wiseman M. The Second World Cancer Research Fund/American Institute For Cancer Research Expert Report: food, nutrition, physical activity, and the prevention of cancer: a global perspective. Proc. Nutr. Soc. 67(3), 253-256 (2008). •• Summary of the dietary and physical activity recommendations for individuals and for public health goals.
39. Goodman GE, Thornquist MD, Balmes J et al. The β-carotene and retinol efficacy trial: incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping β-carotene and retinol supplements. J. Natl Cancer Inst. 96(23), 1743-1750 (2004). (Pubitemid 39654568)
40. Tanvetyanon T, Bepler G. β-carotene in multivitamins and the possible risk of lung cancer among smokers versus former smokers: a meta-analysis and evaluation of national brands. Cancer 113(1), 150-157 (2008). (Pubitemid 351976396)
41. Neuhouser ML, Patterson RE, Thornquist MD et al. Fruits and vegetables are associated with lower lung cancer risk only in the placebo arm of the β-carotene and retinol efficacy trial (CARET). Cancer Epidemiol. Biomarkers Prev. 12(4), 350-358 (2003).
42. Lawenda BD, Kelly KM, Ladas EJ et al. Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? J. Natl Cancer Inst. 100(11), 773-783 (2008). •• Excellent meta-analysis of the clinical trials examining antioxidant administration concurrent to radiation therapy in cancer treatment.
43. Ogle KS, Swanson GM, Woods N, Azzouz F. Cancer and comorbidity: redefining chronic diseases. Cancer 88, 653-663 (2000). (Pubitemid 30056943)
44. Coups EJ, Ostroff JS. A population-based estimate of the prevalence of behavioral risk factors among adult cancer survivors and noncancer controls. Prev. Med. 40(6), 702-711 (2005).
45. Liu CY, Hsu YH, Wu MT et al. Cured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study. BMC Cancer 9, 15 (2009).
46. Sofi F, Cesari F, Abbate R, Gensini GF, Casini A. Adherence to mediterranean diet and health status: meta-analysis. BMJ 337, 1344 (2008).
47. Demark-Wahnefried W, Pinto BM, Gritz ER. Promoting health and physical function among cancer survivors: potential for prevention and questions that remain. J. Clin. Oncol. 24(32), 5125-5131 (2006). • Review of survivorship issues, research summary and clinical guidelines for future directions. (Pubitemid 46623198)
48. Pinto BM, Trunzo JJ. Health behaviors during and after a cancer diagnosis. Cancer 104(11 Suppl.), 2614-2623 (2005).
49. Robien K, Ness KK, Klesges LM, Baker KS, Gurney JG. Poor adherence to dietary guidelines among adult survivors of childhood acute lymphoblastic leukemia. J. Pediatr. Hematol. Oncol. 30(11), 815-822 (2008).
50. Russell NC, Hoelscher DM, Lowenstein N. Patients previously treated for lymphoma consume inadequate or excessive amounts of five key nutrients. J. Soc. Integr. Oncol. 5(3), 118-124 (2007). (Pubitemid 47555912)
51. Moyer-Mileur LJ, Ransdell L, Bruggers CS. Fitness of children with standard-risk acute lymphoblastic leukemia during maintenance therapy: response to a home-based exercise and nutrition program. J. Pediatr. Hematol. Oncol. 31(4), 259-266 (2009).
52. Ness KK, Baker KS, Dengel DR et al. Body composition, muscle strength deficits and mobility limitations in adult survivors of childhood acute lymphoblastic leukemia. Pediatr. Blood Cancer 49(7), 975-981 (2007).
53. Ness KK, Mertens AC, Hudson MM et al. Limitations on physical performance and daily activities among long-term survivors of childhood cancer. Ann. Intern. Med. 143(9), 639-647 (2005).
54. Rai SN, Hudson MM, McCammon E et al. Implementing an intervention to improve bone mineral density in survivors of childhood acute lymphoblastic leukemia: BONEII, a prospective placebo-controlled double-blind randomized interventional longitudinal study design. Contemp. Clin. Trials 29(5), 711-719 (2008).
55. San Juan AF, Chamorro-Viña C, Maté-Muñoz JL et al. Functional capacity of children with leukemia. Int. J. Sports Med. 29(2), 163-167 (2008).
56. San Juan AF, Chamorro-Viña C, Moral S et al. Benefits of intrahospital exercise training after pediatric bone marrow transplantation. Int. J. Sports Med. 29(5), 439-446 (2008). (Pubitemid 351702889)
57. van Brussel M, Takken T, van der Net J et al. Physical function and fitness in long-term survivors of childhood leukaemia. Pediatr. Rehabil. 9(3), 267-274 (2006). (Pubitemid 44582009)
58. Warner JT. Body composition, exercise and energy expenditure in survivors of acute lymphoblastic leukaemia. Pediatr. Blood Cancer 50(2 Suppl.), 456-461 (2008).
59. White J, Flohr JA, Winter SS et al. Potential benefits of physical activity for children with acute lymphoblastic leukaemia. Pediatr. Rehabil. 8(1), 53-58 (2005). (Pubitemid 40127952)
60. Chang P-H, Lai Y-H, Shun S-C et al. Effects of a walking intervention on fatigue-related experiences of hospitalized acute myelogenous leukemia patients undergoing chemotherapy: a randomized controlled trial. J. Pain Symptom Manage. 35(5), 524-534 (2008).
61. Hartman A, te Winkel ML, van Beek RD et al. A randomized trial investigating an exercise program to prevent reduction of bone mineral density and impairment of motor performance during treatment for childhood acute lymphoblastic leukemia. Pediatr. Blood Cancer 53(1), 64-71 (2009).
62. Galvão DA, Taaffe DR, Spry N, Newton RU. Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer. Prostate Cancer Prostatic Dis. 10(4), 340-346 (2007). (Pubitemid 350238081)
63. Hayes SC, Spence RR, Galvao DA, Newton RU. Australian association for exercise and sport science position stand: optimising cancer outcomes through exercise. J. Sci. Med. Sport (4), 428-434 (2009).
64. Jarfelt M, Kujacic V, Holmgren D, Bjarnason R, Lannering B. Exercise echocardiography reveals subclinical cardiac dysfunction in young adult survivors of childhood acute lymphoblastic leukemia. Pediatr. Blood Cancer 49(6), 835-840 (2007). (Pubitemid 47519523)
65. Kelly KM, Thornton JC, Hughes D et al. Total body bone measurements: a cross-sectional study in children with acute lymphoblastic leukemia during and following completion of therapy. Pediatr. Blood Cancer 52(1), 33-38 (2009).
66. Deng G, Lin H, Seidman A et al. A Phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects. J. Cancer Res. Clin. Oncol. 135(9), 1215-1221 (2009).
67. Institute NM. Health and wellness trends database www.nmisolutions.com/ hwtd.html