Design and optimization of a linker for fusion protein construction

Progress in Natural Science

Volumn 19, Issue 10, 2009, Pages 1197-1200

  Zhang, Jianhua ^a   Yun, Jun ^b   Shang, Zhigang ^a   Zhang, Xiaohui ^c   Pan, Borong ^b  

^a ZHENGZHOU UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Design of inter peptide linker; Homology modeling; Improved genetic algorithm; Single chain bispecific antibody

Indexed keywords

CHAINS; GENETIC ALGORITHMS; MOLECULES; PEPTIDES; STRUCTURAL DESIGN; TUMORS;

DESIGN AND OPTIMIZATION; DESIGN OF INTER-PEPTIDE LINKER; FUSION PROTEINS; HOMOLOGY MODELING; IMPROVED GENETIC ALGORITHM; PEPTIDE LINKERS; SINGLE CHAINS; SINGLE-CHAIN ANTIBODIES; SINGLE-CHAIN BISPECIFIC ANTIBODY; SPATIAL STRUCTURE;

ANTIBODIES;

EID: 70350622968     PISSN: 10020071     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnsc.2008.12.007     Document Type: Review

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